Tabloid Proteome is a database of protein association network generated using publically available mass spectrometry based experiments in PRIDE. These associations includes; protein-protein interaction, complex formation, or different role in single pathway.

The association between two proteins are calculated using our method (Gupta et al. 2017) which uses Jaccard Similarity score to calculate the value for association. Our method is based on the assumption that consistent protein co-occurrence across a large collection of different, unrelated MS experiments is not merely due to chance, but that this instead reveals an underlying biological association between these co-occurring proteins. We have also included the biological relation between the protein pairs using existing knowledgebases; IntAct and BioGRID for interaction, CORUM for complex, Ensembl for paralogs, Reactome for pathways, DisGeNet for diseases.

Yes, Tabloid Proteome data are available for free.

You can download your search result as datatable in TSV and CSV format, from Data Table view and as a network image in .png format, from Graph view. You can also download all detected Human or Mosue significantly associating protein pairs in TSV format, from Download tab. If you would like to download information other than these, contact us.

Tabloid proteome include protein-protein interaction only for the protein pairs determined using our association study using public proteomics MS data (Gupta et al. 2017). It does not include protein-protein interaction which are not found in our study.