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Search for the desired protein with Uniprot accession, protein name/keyword, ProteomeXchange ID or PDB id

Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 8 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
231 SER PRIDE yes
249 THR PRIDE
255 SER PRIDE
310 THR PRIDE
311 SER PRIDE
496 SER PRIDE yes
602 SER PRIDE yes
1045 SER PRIDE yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 8 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
231 231 236 1 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD003531 2 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell
249 241 263 9 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
255 241 263 15 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
310 302 315 9 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD005366 1 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture
311 302 315 10 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD005366 1 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture
496 493 502 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
602 600 607 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
1045 1035 1050 11 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001374 1 Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling Homo sapiens (Human) PARTIAL 2015-08-24 HeLa cell

Structures

Showing 2 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
5UGW A X-ray 2.309999942779541 3 A 0.6317657 1045
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
1044 1044 TYR H 0.84 54.269466400146484 0.0
1045 1045 SER H 0.56 58.806884765625 19.558940887451172
4B18 B X-ray 2.5199999809265137 Monomer A 0.0 231
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
231 231 SER C 0.5 105.5151138305664 15.650575637817383

Mutations

Showing 33 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
55 L Q Polymorphism
65 P A Polymorphism
170 V M Disease Pulmonary fibrosis, and/or bone marrow failure, telomere-related, 1 (PFBMFT1) [MIM:614742]
202 A T Disease Aplastic anemia (AA) [MIM:609135]
279 A T Polymorphism
299 V M Polymorphism
412 H Y Disease Dyskeratosis congenita, autosomal recessive, 4 (DKCB4) [MIM:613989]
522 R K Unclassified
570 K N Disease Aplastic anemia (AA) [MIM:609135]
631 R Q Disease Aplastic anemia (AA) [MIM:609135]
682 G D Disease Aplastic anemia (AA) [MIM:609135]
694 V M Disease Pulmonary fibrosis, and/or bone marrow failure, telomere-related, 1 (PFBMFT1) [MIM:614742]
704 P S Disease Dyskeratosis congenita, autosomal recessive, 4 (DKCB4) [MIM:613989]
716 A T Disease Pulmonary fibrosis, and/or bone marrow failure, telomere-related, 1 (PFBMFT1) [MIM:614742]
721 P R Disease Dyskeratosis congenita, autosomal recessive, 4 (DKCB4) [MIM:613989]
726 T M Disease Aplastic anemia (AA) [MIM:609135]
772 Y C Disease Pulmonary fibrosis, and/or bone marrow failure, telomere-related, 1 (PFBMFT1) [MIM:614742]
785 P L Disease Aplastic anemia (AA) [MIM:609135]
791 V I Disease Pulmonary fibrosis, and/or bone marrow failure, telomere-related, 1 (PFBMFT1) [MIM:614742]
811 R C Disease Dyskeratosis congenita, autosomal recessive, 4 (DKCB4) [MIM:613989]
841 L F Disease Pulmonary fibrosis, and/or bone marrow failure, telomere-related, 1 (PFBMFT1) [MIM:614742]
865 R H Disease Pulmonary fibrosis, and/or bone marrow failure, telomere-related, 1 (PFBMFT1) [MIM:614742]
867 V M Disease Pulmonary fibrosis, and/or bone marrow failure, telomere-related, 1 (PFBMFT1) [MIM:614742]
901 R W Disease Dyskeratosis congenita, autosomal recessive, 4 (DKCB4) [MIM:613989]
902 K R Disease Pulmonary fibrosis, and/or bone marrow failure, telomere-related, 1 (PFBMFT1) [MIM:614742]
923 P L Disease Pulmonary fibrosis, and/or bone marrow failure, telomere-related, 1 (PFBMFT1) [MIM:614742]
948 S R Polymorphism
979 R W Disease Dyskeratosis congenita, autosomal dominant, 2 (DKCA2) [MIM:613989]
1025 V F Disease Pulmonary fibrosis, and/or bone marrow failure, telomere-related, 1 (PFBMFT1) [MIM:614742]
1062 A T Polymorphism
1090 V M Disease Pulmonary fibrosis, and/or bone marrow failure, telomere-related, 1 (PFBMFT1) [MIM:614742]
1110 T M Polymorphism
1127 F L Disease Dyskeratosis congenita, autosomal dominant, 2 (DKCA2) [MIM:613989]