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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 6 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
110 THR PRIDE yes
112 SER PRIDE yes
163 TYR PRIDE yes
277 TYR PRIDE yes
281 TYR UP, PRIDE Combined yes
413 THR PRIDE yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 8 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
110 106 126 5 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
112 106 126 7 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
163 160 179 4 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001565 4 Evaluation of phospho-tyrosine antibodies for label-free phosphoproteomics Homo sapiens (Human) PARTIAL 2015-12-09 colon,brain -
PXD003198 1 Characterisation of pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling Homo sapiens (Human) PARTIAL 2016-06-09 pancreatic cell line
277 275 289 3 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 7 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001565 1 Evaluation of phospho-tyrosine antibodies for label-free phosphoproteomics Homo sapiens (Human) PARTIAL 2015-12-09 colon,brain
281 274 289 8 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001565 6 Evaluation of phospho-tyrosine antibodies for label-free phosphoproteomics Homo sapiens (Human) PARTIAL 2015-12-09 colon,brain -
PXD003198 21 Characterisation of pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling Homo sapiens (Human) PARTIAL 2016-06-09 pancreatic cell line
281 275 289 7 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 22 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001565 8 Evaluation of phospho-tyrosine antibodies for label-free phosphoproteomics Homo sapiens (Human) PARTIAL 2015-12-09 colon,brain
PXD003198 4 Characterisation of pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling Homo sapiens (Human) PARTIAL 2016-06-09 pancreatic cell line -
413 406 418 8 4
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD005366 3 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture
PXD004452 2 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -
413 406 416 8 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 9 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture

Structures

Showing 7 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
3QFA A X-ray 2.200000047683716 4 B 0.63061696
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
163 13 TYR E NaN 27.99415397644043 0.0
208 58 THR H NaN 46.41740798950195 0.0
277 127 TYR E NaN 56.36707305908203 0.0
281 131 TYR E NaN 59.372589111328125 0.0
326 176 TYR H NaN 68.98605346679688 0.0
413 263 THR C NaN 108.70768737792969 0.0
2ZZC A X-ray 2.5999999046325684 2 B 0.59415823
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
163 13 TYR E NaN 25.493749618530273 0.0
208 58 THR H NaN 50.460575103759766 0.0
277 127 TYR E NaN 59.48103332519531 0.0
281 131 TYR E NaN 66.8914566040039 0.0
326 176 TYR H NaN 75.88052368164062 0.0
413 263 THR C NaN 104.83599853515625 0.0
3QFB A X-ray 2.5999999046325684 4 B 0.61474323
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
163 13 TYR E NaN 25.380727767944336 0.0
208 58 THR H NaN 48.445980072021484 0.0
277 127 TYR E NaN 61.58253479003906 0.0
281 131 TYR E NaN 59.272987365722656 0.0
326 176 TYR H NaN 71.91097259521484 0.0
413 263 THR C NaN 112.43287658691406 0.0
2CFY A X-ray 2.700000047683716 2 B 0.75477225
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
163 13 TYR E NaN 29.740877151489258 0.0
208 58 THR H NaN 47.64638137817383 0.0
277 127 TYR E NaN 55.117149353027344 0.0
281 131 TYR E NaN 60.512184143066406 0.0
326 176 TYR H NaN 80.61422729492188 0.0
413 263 THR C NaN 102.91590118408203 0.0
2ZZ0 A X-ray 2.799999952316284 2 B 0.54311645
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
163 13 TYR E NaN 25.834592819213867 0.0
208 58 THR H NaN 52.164554595947266 0.0
277 127 TYR E NaN 57.87383270263672 0.0
281 131 TYR E NaN 60.1330451965332 0.0
326 176 TYR H NaN 76.7890853881836 0.0
413 263 THR C NaN 109.1417236328125 0.0
2J3N A X-ray 2.799999952316284 2 B 0.5992383
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
163 13 TYR E NaN 25.642776489257812 0.0
208 58 THR H NaN 48.82810974121094 0.0
277 127 TYR E NaN 66.12972259521484 0.0
281 131 TYR E NaN 60.6165657043457 0.0
326 176 TYR H NaN 76.7595443725586 0.0
413 263 THR C NaN 83.82656860351562 0.0
2ZZB A X-ray 3.200000047683716 2 B 0.52944064
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
163 13 TYR E NaN 32.32432556152344 0.0
208 58 THR H NaN 59.68467712402344 0.0
277 127 TYR E NaN 60.31783676147461 0.0
281 131 TYR E NaN 53.40266418457031 0.0
326 176 TYR H NaN 71.83793640136719 0.0
413 263 THR C NaN 103.15157318115234 0.0

Mutations

Showing 1 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
365 D G Polymorphism