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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 11 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
18 SER UP, PRIDE Combined yes
30 THR PRIDE yes
49 SER UP, PRIDE Similarity yes
54 THR PRIDE yes
74 THR PRIDE
79 SER PRIDE
255 SER PRIDE yes
730 THR PRIDE yes
735 TYR PRIDE yes
963 SER UP, PRIDE Combined yes
1093 TYR PRIDE yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 11 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
18 12 35 7 15
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004252 33 Modulating the selectivity of affinity absorbents to multi-phosphopeptides by a novel competitive substitution strategy Homo sapiens (Human) PARTIAL 2016-08-03 cell culture -
PXD000474 15 Simulated phosphopeptide spectral library for confident site localization Homo sapiens (Human) PARTIAL 2015-03-17 HeLa cell -
PXD004940 28 Performance of the Orbitrap Fusion Lumos Tribrid in single-shot analyses of human samples Homo sapiens (Human) PARTIAL 2017-03-09 HeLa cell -
PXD003531 94 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD001333 7 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell -
PXD002990 3 Complementary Phosphoproteomic Approaches Link IL-23R Downstream Signaling with Metabolic Adaptation in Lymphocytes Homo sapiens (Human) COMPLETE 2016-04-21 lymph node -
PXD006482 15 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney -
PXD002286 390 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 - -
PXD005366 77 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture -
PXD004452 39 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
PXD001550 140 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD000680 116 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -
PXD000612 87 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
PXD001546 65 Reproducibility of label-free single-shot phosphoproteomics applied to CRC cell lines Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD004415 9 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte -
30 12 35 19 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 4 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
49 36 66 14 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
54 36 66 19 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003531 3 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell
74 67 93 8 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
79 67 93 13 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
255 255 262 1 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003531 2 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
730 724 739 7 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
735 724 745 12 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001565 1 Evaluation of phospho-tyrosine antibodies for label-free phosphoproteomics Homo sapiens (Human) PARTIAL 2015-12-09 colon,brain
963 949 968 15 4
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 8 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004415 2 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte -
PXD004452 3 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
PXD001550 1 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
1093 1091 1096 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture

Structures

Showing 49 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
5C56 A X-ray 2.690000057220459 2 B 1.0 730, 735, 963
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
730 730 THR C 0.93 40.93253707885742 0.0
735 735 TYR E 1.0 8.208879470825195 0.0
963 963 SER C 1.0 88.10747528076172 0.0
2YLM A X-ray 2.700000047683716 Monomer [CL]A:1090 0.1 730, 735, 963
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
730 730 THR C 0.93 34.02191162109375 0.0
735 735 TYR E 1.0 5.690367698669434 0.0
963 963 SER C 1.0 32.547943115234375 0.0
4Z96 A X-ray 2.8499999046325684 2 C 1.0 730, 735, 963
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
730 730 THR C 0.93 34.063941955566406 0.0
735 735 TYR E 1.0 5.592658042907715 0.0
963 963 SER C 1.0 29.70160484313965 0.0
4YOC C X-ray 2.9200000762939453 Monomer A 0.0 730, 735, 963
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
730 730 THR C 0.93 32.992252349853516 0.0
735 735 TYR E 1.0 4.356157302856445 0.0
963 963 SER C 1.0 69.48348236083984 17.740612030029297
4Z97 A X-ray 3.0 2 C 0.7358103 730, 735, 963
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
730 730 THR C 0.93 34.11429977416992 0.0
735 735 TYR E 1.0 8.274710655212402 0.0
963 963 SER C 1.0 32.396629333496094 0.0
2F1Z A X-ray 3.200000047683716 Monomer B 0.0 74, 79, 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 56.40910339355469 0.0
79 79 SER C 0.94 54.64443588256836 0.0
255 255 SER C 1.0 9.963111877441406 0.0
5J7T A X-ray 3.200000047683716 Monomer A 0.0 255, 730, 735
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 8.800601959228516 0.0
730 730 THR C 0.93 24.675121307373047 0.0
735 735 TYR E 1.0 10.410734176635742 0.0
5JTV A X-ray 3.309999942779541 4 E 1.0 255, 963, 1093
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 4.64089822769165 0.0
963 963 SER C 1.0 34.409629821777344 0.0
1092 1092 THR C 0.96 77.08007049560547 0.0
1093 1093 TYR C 0.96 220.69313049316406 0.8579059839248657
5FWI C X-ray 3.4000000953674316 2 C 0.1 255, 730, 735
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 11.498907089233398 0.0
730 730 THR C 0.93 29.071659088134766 0.0
735 735 TYR E 1.0 7.227579116821289 0.0
4YSI A X-ray 1.0199999809265137 2 B 0.10171235 74, 79
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 56.62678146362305 0.0
79 79 SER H 0.94 58.880859375 0.0
2XXN A X-ray 1.600000023841858 2 B 1.0 74, 79
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 59.79191207885742 0.0
79 79 SER H 0.94 60.61598587036133 0.0
2FOJ A X-ray 1.600000023841858 2 B 0.1 74, 79
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 57.459468841552734 0.0
79 79 SER H 0.94 63.9168701171875 0.0
2F1W A X-ray 1.649999976158142 Monomer [CA]A:301 0.050866388 74, 79
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 60.18402862548828 0.0
79 79 SER H 0.94 62.76924514770508 0.0
2F1Y A X-ray 1.7000000476837158 Monomer A 0.0 74, 79
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 62.779884338378906 0.0
79 79 SER H 0.94 60.0960578918457 0.0
1YY6 A X-ray 1.7000000476837158 2 [NA]A:1005 0.08771436 74, 79
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 58.32929229736328 0.0
79 79 SER H 0.94 62.93593215942383 0.0
4KG9 A X-ray 1.7000000476837158 2 B 0.1 74, 79
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 57.871421813964844 0.0
79 79 SER H 0.94 58.687591552734375 0.0
3MQR A X-ray 1.7999999523162842 2 B 1.0 74, 79
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 58.28766632080078 0.0
79 79 SER H 0.94 62.58564758300781 0.0
4JJQ A X-ray 1.9500000476837158 2 B 1.0 74, 79
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 59.14910125732422 0.0
79 79 SER H 0.94 62.62594223022461 0.0
2FOP A X-ray 2.0999999046325684 2 B 0.1 74, 79
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 58.637203216552734 0.0
79 79 SER H 0.94 64.5177001953125 0.0
2FOO A X-ray 2.200000047683716 2 B 0.1 74, 79
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 57.256595611572266 0.0
79 79 SER H 0.94 61.826087951660156 0.0
5C6D A X-ray 2.2899999618530273 3 B 1.0 730, 735
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
730 730 THR C 0.93 30.484079360961914 0.0
735 735 TYR E 1.0 6.71986198425293 0.0
2F1X A X-ray 2.299999952316284 Monomer A 0.0 74, 79
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 50.36124801635742 17.991596221923828
79 79 SER H 0.94 58.13378143310547 0.0
3MQS C X-ray 2.4000000953674316 2 D 0.1 74, 79
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 57.55973434448242 0.0
79 79 SER H 0.94 61.08295440673828 0.0
4PYZ A X-ray 2.8399999141693115 Monomer B 0.0 730, 735
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
730 730 THR C 0.93 29.822437286376953 0.0
735 735 TYR E 1.0 6.952525615692139 0.0
4WPH A X-ray 2.9200000762939453 4 D 0.56521946 730, 735
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
730 730 THR C 0.93 37.819580078125 0.0
735 735 TYR E 1.0 8.462457656860352 0.0
5GG4 A X-ray 3.109999895095825 2 B 1.0 730, 735
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
730 730 THR C 0.93 33.061832427978516 0.0
735 735 TYR E 1.0 6.501805782318115 0.0
5JTJ A X-ray 3.319999933242798 8 B 1.0 255, 1093
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 8.724149703979492 0.0
1093 1093 TYR C 0.96 246.91781616210938 0.0
4WPI A X-ray 3.4000000953674316 4 D 0.50828844 730, 735
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
730 730 THR C 0.93 30.926746368408203 0.0
735 735 TYR E 1.0 11.088245391845703 0.0
5KYC B X-ray 1.4299999475479126 2 C 0.615615 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 9.7025785446167 0.0
5KYF B X-ray 1.4500000476837158 2 C 0.95975715 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 10.721477508544922 0.0
5KYD A X-ray 1.6200000047683716 2 D 1.0 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 12.20783805847168 0.0
5N9T A X-ray 1.7300000190734863 Monomer [SO4]A:1001 0.08970359 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 10.883261680603027 0.0
5VSB A X-ray 1.850000023841858 Monomer [9QA]A:4000 0.1 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 8.18797779083252 0.0
5KYE A X-ray 1.9700000286102295 4 D 1.0 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 9.874470710754395 0.0
1YZE A X-ray 2.0 Monomer A 0.0 74
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
74 74 THR E 0.97 46.190940856933594 0.0
6F5H A X-ray 2.1600000858306885 Monomer [SO4]A:1001 0.08768275 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 13.4638671875 0.0
4M5X A X-ray 2.190000057220459 Monomer [BR]A:602 0.1 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 9.734232902526855 0.0
5KYB A X-ray 2.200000047683716 Monomer [GOL]A:601 0.1 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 9.15909194946289 0.0
5UQX A X-ray 2.2300000190734863 Monomer A 0.0 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 10.931401252746582 0.0
5N9R A X-ray 2.2300000190734863 Monomer [SO4]A:1001 0.086472005 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 12.195067405700684 0.0
4M5W A X-ray 2.240000009536743 Monomer [BR]A:603 0.03283984 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 11.865030288696289 0.0
5VS6 A X-ray 2.2699999809265137 2 [9QD]A:601 0.11527304 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 13.435306549072266 0.0
1NBF A X-ray 2.299999952316284 2 D 0.9099644 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 9.397618293762207 0.0
1NB8 A X-ray 2.299999952316284 Monomer B 0.0 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 10.721151351928711 0.0
5NGF A X-ray 2.3299999237060547 Monomer [8WN]A:601 0.11284437 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 10.299816131591797 0.0
5NGE A X-ray 2.3499999046325684 Monomer [8WK]A:601 0.1 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 12.304587364196777 0.0
5WHC A X-ray 2.549999952316284 Monomer [GOL]A:602 0.31665376 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 17.054391860961914 0.0
5UQV A X-ray 2.8399999141693115 2 B 0.1 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 12.331235885620117 0.0
5VSK A X-ray 3.3299999237060547 2 [ZN]A:603 0.31776866 255
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
255 255 SER C 1.0 11.817591667175293 0.0

Mutations

Showing 0 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease