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Search for the desired protein with Uniprot accession, protein name/keyword, ProteomeXchange ID or PDB id

Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 10 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
15 SER PRIDE yes
22 THR PRIDE yes
35 SER UP, PRIDE Combined yes
39 SER PRIDE yes
42 SER PRIDE yes
100 SER UP, PRIDE Combined yes
107 SER PRIDE yes
109 TYR PRIDE yes
121 SER PRIDE yes
162 TYR PRIDE yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 16 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
15 13 24 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD002286 1 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 -
22 13 28 10 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 2 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
35 29 43 7 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 4 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
35 30 43 6 7
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000836 31 HOPE-fixation of lung tissue allows retrospective proteome and phosphoproteome studies Homo sapiens (Human) PARTIAL 2014-05-22 lung -
PXD000612 17 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004415 5 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte
PXD003531 2 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD004452 12 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
PXD001550 4 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD000680 2 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -
35 30 44 6 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004415 3 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte
35 31 43 5 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000836 13 HOPE-fixation of lung tissue allows retrospective proteome and phosphoproteome studies Homo sapiens (Human) PARTIAL 2014-05-22 lung -
PXD000612 51 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
35 31 44 5 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000836 2 HOPE-fixation of lung tissue allows retrospective proteome and phosphoproteome studies Homo sapiens (Human) PARTIAL 2014-05-22 lung
39 30 43 10 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 2 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
39 31 43 9 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000836 2 HOPE-fixation of lung tissue allows retrospective proteome and phosphoproteome studies Homo sapiens (Human) PARTIAL 2014-05-22 lung
PXD000612 5 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
42 30 43 13 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
100 97 112 4 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004415 5 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte -
PXD004452 2 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
107 97 112 11 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
109 97 112 13 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
121 113 127 9 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
121 115 127 7 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 5 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
162 155 163 8 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001565 2 Evaluation of phospho-tyrosine antibodies for label-free phosphoproteomics Homo sapiens (Human) PARTIAL 2015-12-09 colon,brain

Structures

Showing 5 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
6CG0 N EM 3.17 Monomer M 0.0 15, 22, 35, 39, 42, 100, 107, 109, 121
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
15 15 SER C 1.0 137.70004272460938 13.11565113067627
16 16 TYR C 1.0 157.3384552001953 94.15643310546875
22 22 THR H 1.0 82.6845474243164 0.0
35 35 SER C 1.0 148.0415496826172 0.0
39 39 SER C 0.74 98.95963287353516 19.698095321655273
42 42 SER H 1.0 90.88479614257812 71.81534576416016
100 100 SER C 1.0 72.39566802978516 0.0
107 107 SER H 0.52 75.6089096069336 36.22064208984375
109 109 TYR H 0.69 87.00450897216797 0.0
121 121 SER C 0.83 87.99654388427734 0.0
6CIJ N EM 3.9 Monomer M 0.0 15, 22, 35, 39, 42, 100, 107, 109, 121
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
15 15 SER C 1.0 46.174251556396484 14.29584789276123
16 16 TYR C 1.0 126.78294372558594 97.23271942138672
22 22 THR H 1.0 33.24820327758789 0.0
35 35 SER C 1.0 93.5404052734375 0.0
39 39 SER H 0.74 74.18807220458984 15.996919631958008
42 42 SER H 1.0 66.62833404541016 55.06071472167969
100 100 SER C 1.0 48.299888610839844 0.0
107 107 SER H 0.52 75.30026245117188 22.069927215576172
109 109 TYR H 0.69 88.934814453125 0.0
121 121 SER C 0.83 76.61117553710938 0.0
6CIK N X-ray 3.15 10 G 0.077397026 22, 35, 39, 42, 100, 107, 109, 121
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
22 22 THR H 1.0 71.67139434814453 0.0
35 35 SER C 1.0 107.4834213256836 9.877604484558105
39 39 SER H 0.74 73.06932067871094 0.0
42 42 SER H 1.0 66.3551025390625 3.013721227645874
100 100 SER C 1.0 58.1928825378418 31.953948974609375
107 107 SER H 0.52 83.3207015991211 0.0
109 109 TYR H 0.69 99.25984191894531 0.0
121 121 SER C 0.83 70.61009979248047 0.747849702835083
6CIM N X-ray 3.6 10 G 0.087670565 22, 35, 39, 42, 100, 107, 109, 121
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
22 22 THR H 1.0 69.95310974121094 0.0
35 35 SER C 1.0 108.60148620605469 14.698138236999512
39 39 SER H 0.74 73.95655822753906 0.0
42 42 SER H 1.0 62.6668701171875 3.1820809841156006
100 100 SER C 1.0 61.085662841796875 31.272605895996094
107 107 SER H 0.52 80.19831085205078 0.0
109 109 TYR H 0.69 72.7579345703125 0.0
121 121 SER C 0.83 69.54658508300781 0.31516653299331665
2LY4 A NMR Monomer B 0.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
15 14 SER H 1.0 7.610827445983887 0.0
16 15 TYR H 1.0 77.38453674316406 35.30480194091797
22 21 THR H 1.0 54.531150817871094 0.0
35 34 SER C 1.0 87.10911560058594 26.12305450439453
39 38 SER H 0.74 93.06256103515625 46.596736907958984
42 41 SER H 1.0 52.56441116333008 51.82750701904297
51 50 THR C 1.0 114.3625717163086 0.0

Mutations

Showing 4 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
11 G R Unclassified Gastric-carcinoma cell line
149 A E Unclassified Gastric-carcinoma cell line
156 E Q Polymorphism
190 D G Unclassified Gastric-carcinoma cell line