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PDB 
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Phospho-sites

Showing 5 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
749 SER PRIDE yes
1544 THR PRIDE yes
2192 SER PRIDE yes
2290 THR PRIDE yes
2309 SER PRIDE yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 6 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
749 742 761 8 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD005366 1 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture
1544 1542 1551 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
2192 2166 2195 27 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
2192 2170 2193 23 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD002286 2 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 -
2290 2285 2295 6 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
2309 2305 2329 5 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 4 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon

Structures

Showing 0 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure

Mutations

Showing 54 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
21 A V Polymorphism
101 E Q Disease Epileptic encephalopathy, early infantile, 42 (EIEE42) [MIM:617106]
192 R Q Disease Migraine, familial hemiplegic, 1 (FHM1) [MIM:141500]
195 R K Disease Migraine, familial hemiplegic, 1 (FHM1) [MIM:141500]
218 S L Disease Migraine, familial hemiplegic, 1 (FHM1) [MIM:141500]
248 Y C Disease Episodic ataxia 2 (EA2) [MIM:108500]
253 H Y Disease Episodic ataxia 2 (EA2) [MIM:108500]
256 C R Disease Episodic ataxia 2 (EA2) [MIM:108500]
287 C Y Disease Episodic ataxia 2 (EA2) [MIM:108500]
293 G R Disease Spinocerebellar ataxia 6 (SCA6) [MIM:183086]
388 E K Disease Episodic ataxia 2 (EA2) [MIM:108500]
389 L F Disease Episodic ataxia 2 (EA2) [MIM:108500]
405 A T Disease Spinocerebellar ataxia 6 (SCA6) [MIM:183086]
453 A T Polymorphism
500 T M Disease Episodic ataxia 2 (EA2) [MIM:108500]
582 R Q Disease Spinocerebellar ataxia 6 (SCA6) [MIM:183086]
637 G D Disease Episodic ataxia 2 (EA2) [MIM:108500]
665 T M Disease Migraine, familial hemiplegic, 1 (FHM1) [MIM:141500]
712 A T Disease Epileptic encephalopathy, early infantile, 42 (EIEE42) [MIM:617106]
713 V A Disease Migraine, familial hemiplegic, 1 (FHM1) [MIM:141500]
714 D E Disease Migraine, familial hemiplegic, 1 (FHM1) [MIM:141500]
731 E A Polymorphism
797 M T Disease Episodic ataxia 2 (EA2) [MIM:108500]
896 P R Disease Episodic ataxia 2 (EA2) [MIM:108500]
913 P S Polymorphism
917 E D Polymorphism
992 E V Polymorphism
1014 E K Polymorphism
1104 G S Polymorphism
1172 P L Polymorphism
1334 K E Disease Migraine, familial hemiplegic, 1 (FHM1) [MIM:141500]
1337 D Y Disease Spinocerebellar ataxia 6 (SCA6) [MIM:183086]
1345 R Q Disease Migraine, familial hemiplegic, 1 (FHM1) [MIM:141500]
1383 Y C Disease Migraine, familial hemiplegic, 1 (FHM1) [MIM:141500]
1402 F C Disease Episodic ataxia 2 (EA2) [MIM:108500]
1435 W R Disease Epileptic encephalopathy, early infantile, 42 (EIEE42) [MIM:617106]
1455 V L Disease Migraine, familial hemiplegic, 1 (FHM1) [MIM:141500]
1481 G R Disease Episodic ataxia 2 (EA2) [MIM:108500]
1489 F S Disease Episodic ataxia 2 (EA2) [MIM:108500]
1492 V I Disease Episodic ataxia 2 (EA2) [MIM:108500]
1507 A S Disease Epileptic encephalopathy, early infantile, 42 (EIEE42) [MIM:617106]
1660 R H Disease Episodic ataxia 2 (EA2) [MIM:108500]
1663 R Q Disease Spinocerebellar ataxia 6 (SCA6) [MIM:183086]
1666 R W Disease Migraine, familial hemiplegic, 1 (FHM1) [MIM:141500]
1672 R P Polymorphism
1678 R C Disease Episodic ataxia 2 (EA2) [MIM:108500]
1682 W R Disease Migraine, familial hemiplegic, 1 (FHM1) [MIM:141500]
1694 V I Disease Migraine, familial hemiplegic, 1 (FHM1) [MIM:141500]
1735 H L Disease Episodic ataxia 2 (EA2) [MIM:108500]
1755 E K Disease Episodic ataxia 2 (EA2) [MIM:108500]
1809 I L Disease Migraine, familial hemiplegic, 1 (FHM1) [MIM:141500]
1868 C R Disease Episodic ataxia 2 (EA2) [MIM:108500]
2134 R C Disease Episodic ataxia 2 (EA2) [MIM:108500]
2395 P S Polymorphism