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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 6 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
79 SER PRIDE yes
81 SER PRIDE yes
124 SER PRIDE
146 THR PRIDE yes
147 SER UP, PRIDE Combined yes
299 SER UP, PRIDE Combined yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 9 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
79 75 91 5 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003531 3 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell
79 77 91 3 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004252 5 Modulating the selectivity of affinity absorbents to multi-phosphopeptides by a novel competitive substitution strategy Homo sapiens (Human) PARTIAL 2016-08-03 cell culture -
PXD003531 8 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD001333 5 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell
81 77 91 5 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003531 1 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell
124 122 150 3 6
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001546 7 Reproducibility of label-free single-shot phosphoproteomics applied to CRC cell lines Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD004415 3 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte -
PXD003531 8 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD002286 20 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 - -
PXD004452 8 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
PXD001550 12 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
124 122 153 3 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001550 1 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture
PXD004452 3 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
146 122 153 25 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 2 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
PXD005366 1 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture -
PXD004452 9 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
146 122 150 25 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD002286 2 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 -
147 122 150 26 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001550 1 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -
299 291 302 9 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 3 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture

Structures

Showing 0 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure

Mutations

Showing 23 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
42 E D Unclassified Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
183 R P Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
216 L R Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
237 L P Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
241 G W Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
333 V E Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
360 R S Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
363 V D Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
456 Y C Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
462 T I Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
470 L S Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
505 G R Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
508 R W Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
511 N K Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
518 G E Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
547 V G Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
550 V M Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
571 D N Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
581 G S Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
582 G R Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
615 D Y Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
634 D N Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]
715 D G Disease Holocarboxylase synthetase deficiency (HLCS deficiency) [MIM:253270]