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CDK2_HUMAN : Cyclin-dependent kinase 2

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MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL20406080100120140160180200220240260280Protein Sequence
PDB 
 AlphaFold
Phospho-sites

Showing 5 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
14 THR UP, PRIDE Experimental
15 TYR UP, PRIDE Combined
19 TYR UP, PRIDE Combined yes
158 THR PRIDE yes
160 THR UP, PRIDE Experimental yes

3D structure is not available

5LMK

Display Settings

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

P24941Cyclin-dependent kinase 2

Outer ring: early folding

  • early folding
  • non-early folding

Ring 2: backbone dynamics

  • flexible
  • context dependent
  • rigid

Ring 3: disordered propensity

  • ordered
  • disordered

Ring 4: secondary structure

  • Coil (C)
  • Sheet (E)
  • Helix (H)

Inner ring: amino Acids

  • unphosphorylated
  • phosphorylated

Phospho peptides

Showing 9 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
IGEGTYGVVYK 14 10 20 5 16
IGEGTYGVVYKAR 14 10 22 5 1
VEKIGEGTYGVVYK 15 7 20 9 4
VEKIGEGTYGVVYKAR 15 7 22 9 2
IGEGTYGVVYK 15 10 20 6 17
IGEGTYGVVYKAR 15 10 22 6 3
IGEGTYGVVYK 19 10 20 10 6
AFGVPVRTYTHEVVTLWYR 158 151 169 8 1
TYTHEVVTLWYR 160 158 169 3 7

Structures

Showing 382 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
5LMK A X-ray 2.4 2 B 0.84613574 14, 14, 15, 15, 19, 19, 158, 158
2V22 A X-ray 2.6 2 B 0.79532266 14, 15, 19, 158, 160, 160
4EK4 A X-ray 1.26 Monomer [NA]A:302 0.022765445 14, 15, 19, 158, 160
4FKL A X-ray 1.26 Monomer [ACE]A:0 1.0 14, 15, 19, 158, 160
2R3I A X-ray 1.28 Monomer [SCF]A:501 0.065721504 14, 15, 19, 158, 160
5MHQ A X-ray 1.3 Monomer A 0.0 14, 15, 19, 158, 160
1GZ8 A X-ray 1.3 Monomer A 0.0 14, 15, 19, 158, 160
4EK3 A X-ray 1.34 Monomer [ACE]A:0 0.1 14, 15, 19, 158, 160
2R3Q A X-ray 1.35 Monomer [5SC]A:501 0.06731774 14, 15, 19, 158, 160
4GCJ A X-ray 1.42 Monomer [X64]A:305 0.20467521 14, 15, 19, 158, 160
2R3R A X-ray 1.47 Monomer [6SC]A:501 0.06316099 14, 15, 19, 158, 160
4FKU A X-ray 1.47 Monomer [ACE]A:0 0.043421015 14, 15, 19, 158, 160
2R3F A X-ray 1.5 Monomer [SC8]A:501 0.088306256 14, 15, 19, 158, 160
2R3H A X-ray 1.5 Monomer [SCE]A:501 0.08041032 14, 15, 19, 158, 160
4FKG A X-ray 1.51 Monomer [4CK]A:300 0.07815747 14, 15, 19, 158, 160
4FKO A X-ray 1.55 Monomer [20K]A:301 0.047251035 14, 15, 19, 158, 160
2R3G A X-ray 1.55 Monomer [SC9]A:501 0.07330741 14, 15, 19, 158, 160
4FKI A X-ray 1.6 Monomer [ACE]A:0 0.099972785 14, 15, 19, 158, 160
5OO0 A X-ray 1.6 Monomer A 0.0 14, 15, 19, 158, 160
4EK5 A X-ray 1.6 Monomer [03K]A:300 0.08033923 14, 15, 19, 158, 160
4RJ3 A X-ray 1.63 Monomer [ACT]A:301 0.69782835 14, 15, 19, 158, 160
2R3P A X-ray 1.66 Monomer [3SC]A:501 0.08959883 14, 15, 19, 158, 160
3PXZ A X-ray 1.7 Monomer A 0.0 14, 15, 19, 158, 160
3RAI A X-ray 1.7 Monomer A 0.0 14, 15, 19, 158, 160
3QQJ A X-ray 1.7 Monomer [PO4]A:301 0.08463587 14, 15, 19, 158, 160
3R73 A X-ray 1.7 Monomer [X87]A:920 0.11491603 14, 15, 19, 158, 160
4KD1 A X-ray 1.7 Monomer [1QK]A:302 0.38375658 14, 15, 19, 158, 160
5ANE A X-ray 1.7 Monomer A 0.0 14, 15, 19, 158, 160
3QQF A X-ray 1.75 Monomer [X07]A:543 0.27308646 14, 15, 19, 158, 160
3PY0 A X-ray 1.75 Monomer [PO4]A:300 0.27571708 14, 15, 19, 158, 160
3ROY A X-ray 1.75 Monomer [22Z]A:781 0.14183657 14, 15, 19, 158, 160
3QWJ A X-ray 1.75 Monomer [X6A]A:483 0.11764335 14, 15, 19, 158, 160
3QXO A X-ray 1.75 Monomer [X65]A:668 0.16842224 14, 15, 19, 158, 160
3R71 A X-ray 1.75 Monomer [X86]A:800 0.111592956 14, 15, 19, 158, 160
3QXP A X-ray 1.75 Monomer [X64]A:300 0.11269735 14, 15, 19, 158, 160
3R6X A X-ray 1.75 Monomer [X84]A:778 0.11250181 14, 15, 19, 158, 160
3QZG A X-ray 1.75 Monomer A 0.0 14, 15, 19, 158, 160
3QRT A X-ray 1.75 Monomer A 0.0 14, 15, 19, 158, 160
3RPO A X-ray 1.75 Monomer [24Z]A:778 0.11641314 14, 15, 19, 158, 160
3QZI A X-ray 1.75 Monomer [X72]A:512 0.114705645 14, 15, 19, 158, 160
3R83 A X-ray 1.75 Monomer [Z14]A:589 0.16706824 14, 15, 19, 158, 160
3QX2 A X-ray 1.75 Monomer [X63]A:300 0.11925917 14, 15, 19, 158, 160
3R28 A X-ray 1.75 Monomer [XA0]A:782 0.11702063 14, 15, 19, 158, 160
5OSM A X-ray 1.77 Monomer A 0.0 14, 15, 19, 158, 160
3NS9 A X-ray 1.78 Monomer [NS9]A:0 0.1 14, 15, 19, 158, 160
1H01 A X-ray 1.79 Monomer [FBL]A:302 0.026965665 14, 15, 19, 158, 160
3R1S A X-ray 1.8 Monomer [X73]A:647 0.11297602 14, 15, 19, 158, 160
3PXY A X-ray 1.8 Monomer [PO4]A:300 0.09046071 14, 15, 19, 158, 160
2CLX A X-ray 1.8 Monomer A 0.0 14, 15, 19, 158, 160
3RK7 A X-ray 1.8 Monomer [08Z]A:467 0.1332733 14, 15, 19, 158, 160
3S00 A X-ray 1.8 Monomer [Z60]A:461 0.1 14, 15, 19, 158, 160
2EXM A X-ray 1.8 Monomer A 0.0 14, 15, 19, 158, 160
3QTQ A X-ray 1.8 Monomer A 0.0 14, 15, 19, 158, 160
3IGG A X-ray 1.8 Monomer A 0.0 14, 15, 19, 158, 160
3RPV A X-ray 1.8 Monomer [26Z]A:495 0.11644064 14, 15, 19, 158, 160
3R1Y A X-ray 1.8 Monomer [X76]A:488 0.111704595 14, 15, 19, 158, 160
3PXF A X-ray 1.8 Monomer A 0.0 14, 15, 19, 158, 160
1YKR A X-ray 1.8 Monomer [628]A:299 0.1 14, 15, 19, 158, 160
2C6I A X-ray 1.8 Monomer A 0.0 14, 15, 19, 158, 160
1HCL A X-ray 1.8 Monomer A 0.0 14, 15, 19, 158, 160
3R8P A X-ray 1.8 Monomer [Z46]A:511 0.1 14, 15, 19, 158, 160
2R3O A X-ray 1.8 Monomer [2SC]A:501 0.0625895 14, 15, 19, 158, 160
3QTU A X-ray 1.82 Monomer [X44]A:451 0.1 14, 15, 19, 158, 160
5OSJ A X-ray 1.83 Monomer A 0.0 14, 15, 19, 158, 160
3TIY A X-ray 1.84 Monomer A 0.0 14, 15, 19, 158, 160
2FVD A X-ray 1.85 Monomer A 0.0 14, 15, 19, 158, 160
1E1X A X-ray 1.85 Monomer A 0.0 14, 15, 19, 158, 160
2B54 A X-ray 1.85 Monomer [D05]A:300 0.1 14, 15, 19, 158, 160
3RJC A X-ray 1.85 Monomer A 0.0 14, 15, 19, 158, 160
3QWK A X-ray 1.85 Monomer [X62]A:493 0.30556253 14, 15, 19, 158, 160
2VU3 A X-ray 1.85 Monomer [LZE]A:1299 0.1 14, 15, 19, 158, 160
2XNB A X-ray 1.85 Monomer [Y8L]A:1299 0.1 14, 15, 19, 158, 160
3RM7 A X-ray 1.85 Monomer [19Z]A:654 0.10911058 14, 15, 19, 158, 160
3QTW A X-ray 1.85 Monomer A 0.0 14, 15, 19, 158, 160
3RK9 A X-ray 1.85 Monomer [09Z]A:483 0.1 14, 15, 19, 158, 160
1H07 A X-ray 1.85 Monomer [ACE]A:0 0.07953828 14, 15, 19, 158, 160
3SQQ A X-ray 1.85 Monomer [99Z]A:456 0.11975582 14, 15, 19, 158, 160
3QQL A X-ray 1.85 Monomer [X03]A:299 0.1 14, 15, 19, 158, 160
3R1Q A X-ray 1.85 Monomer [X75]A:616 0.110816434 14, 15, 19, 158, 160
3QQK A X-ray 1.86 Monomer A 0.0 14, 15, 19, 158, 160
3QQH A X-ray 1.87 Monomer [X0A]A:303 0.05751628 14, 15, 19, 158, 160
3QL8 A X-ray 1.9 Monomer [X01]A:300 0.12570594 14, 15, 19, 158, 160
3QQG A X-ray 1.9 Monomer [PO4]A:301 0.056167368 14, 15, 19, 158, 160
1HCK A X-ray 1.9 Monomer [ATP]A:400 0.034659855 14, 15, 19, 158, 160
3UNJ A X-ray 1.9 Monomer [PO4]A:300 0.059178334 14, 15, 19, 158, 160
2VTR A X-ray 1.9 Monomer [LZB]A:1299 0.1 14, 15, 19, 158, 160
3R8V A X-ray 1.9 Monomer [Z62]A:473 0.1 14, 15, 19, 158, 160
2XMY A X-ray 1.9 Monomer [CDK]A:500 0.1 14, 15, 19, 158, 160
3R8L A X-ray 1.9 Monomer A 0.0 14, 15, 19, 158, 160
3R7E A X-ray 1.9 Monomer [X88]A:919 0.17417356 14, 15, 19, 158, 160
2C6M A X-ray 1.9 Monomer A 0.0 14, 15, 19, 158, 160
3PXQ A X-ray 1.9 Monomer A 0.0 14, 15, 19, 158, 160
2C6K A X-ray 1.9 Monomer A 0.0 14, 15, 19, 158, 160
3R7Y A X-ray 1.9 Monomer [Z04]A:484 0.14286758 14, 15, 19, 158, 160
1OIR A X-ray 1.91 Monomer A 0.0 14, 15, 19, 158, 160
3QX4 A X-ray 1.92 Monomer [X4B]A:454 0.115553916 14, 15, 19, 158, 160
5JQ5 A X-ray 1.94 Monomer [I74]A:302 0.07317384 14, 15, 19, 158, 160
3QU0 A X-ray 1.95 Monomer [X40]A:454 0.17905466 14, 15, 19, 158, 160
3QZH A X-ray 1.95 Monomer [X69]A:839 0.11630452 14, 15, 19, 158, 160
3R9D A X-ray 1.95 Monomer [X6B]A:590 0.1 14, 15, 19, 158, 160
1PXI A X-ray 1.95 Monomer [CK1]A:500 0.1 14, 15, 19, 158, 160
3RNI A X-ray 1.95 Monomer [21Z]A:424 0.1 14, 15, 19, 158, 160
3QRU A X-ray 1.95 Monomer [X19]A:493 0.10478918 14, 15, 19, 158, 160
3R7V A X-ray 1.95 Monomer [Z02]A:490 0.12048935 14, 15, 19, 158, 160
1PW2 A X-ray 1.95 Monomer A 0.0 14, 15, 19, 158, 160
3QTX A X-ray 1.95 Monomer [X43]A:299 0.1 14, 15, 19, 158, 160
2A0C X X-ray 1.95 Monomer [CK9]X:500 0.1 14, 15, 19, 158, 160
2C68 A X-ray 1.95 Monomer [CT6]A:1297 0.1 14, 15, 19, 158, 160
1E1V A X-ray 1.95 Monomer [ACE]A:0 0.1136021 14, 15, 19, 158, 160
1JSV A X-ray 1.96 Monomer [U55]A:400 0.1 14, 15, 19, 158, 160
1PXO A X-ray 1.96 Monomer A 0.0 14, 15, 19, 158, 160
3TI1 A X-ray 1.99 Monomer A 0.0 14, 15, 19, 158, 160
3RK5 A X-ray 2.0 Monomer [07Z]A:436 0.1 14, 15, 19, 158, 160
3RKB A X-ray 2.0 Monomer [12Z]A:457 0.14519502 14, 15, 19, 158, 160
2B53 A X-ray 2.0 Monomer A 0.0 14, 15, 19, 158, 160
3S0O A X-ray 2.0 Monomer [50Z]A:446 0.1 14, 15, 19, 158, 160
4EZ3 A X-ray 2.0 Monomer [0S0]A:301 0.15634614 14, 15, 19, 158, 160
3PXR A X-ray 2.0 Monomer A 0.0 14, 15, 19, 158, 160
4ERW A X-ray 2.0 Monomer A 0.0 14, 15, 19, 158, 160
1Y8Y A X-ray 2.0 Monomer [CT7]A:401 0.1 14, 15, 19, 158, 160
3LE6 A X-ray 2.0 Monomer [2BZ]A:299 0.1 14, 15, 19, 158, 160
3QZF A X-ray 2.0 Monomer A 0.0 14, 15, 19, 158, 160
2DS1 A X-ray 2.0 Monomer [1CD]A:501 0.1 14, 15, 19, 158, 160
2VTL A X-ray 2.0 Monomer A 0.0 14, 15, 19, 158, 160
3QTZ A X-ray 2.0 Monomer [X42]A:453 0.13794196 14, 15, 19, 158, 160
1B38 A X-ray 2.0 Monomer [ATP]A:381 0.031522896 14, 15, 19, 158, 160
3R8U A X-ray 2.0 Monomer [Z31]A:465 0.1 14, 15, 19, 158, 160
3TIZ A X-ray 2.02 Monomer A 0.0 14, 15, 19, 158, 160
3LFQ A X-ray 2.03 Monomer [A28]A:299 0.1 14, 15, 19, 158, 160
3PY1 A X-ray 2.05 Monomer A 0.0 14, 15, 19, 158, 160
1W8C A X-ray 2.05 Monomer [ACE]A:0 0.053906675 14, 15, 19, 158, 160
2UUE A X-ray 2.06 3 B 1.0 14, 15, 19, 158, 160
2C6O A X-ray 2.1 Monomer [4SP]A:1297 0.1 14, 15, 19, 158, 160
3UNK A X-ray 2.1 Monomer [PO4]A:300 0.046789378 14, 15, 19, 158, 160
3R9H A X-ray 2.1 Monomer [Z67]A:606 0.1 14, 15, 19, 158, 160
2C69 A X-ray 2.1 Monomer A 0.0 14, 15, 19, 158, 160
2C5N A X-ray 2.1 4 B 0.94044435 14, 15, 19, 158, 160
2C5O A X-ray 2.1 2 B 1.0 14, 15, 19, 158, 160
1B39 A X-ray 2.1 Monomer [ATP]A:381 0.03625457 14, 15, 19, 158, 160
2V0D A X-ray 2.2 Monomer [CL]A:1300 0.16027695 14, 15, 19, 158, 160
2VTM A X-ray 2.25 Monomer A 0.0 14, 15, 19, 158, 160
2C5Y A X-ray 2.25 Monomer A 0.0 14, 15, 19, 158, 160
1FIN A X-ray 2.3 2 B 0.96401674 14, 15, 19, 158, 160
1VYW A X-ray 2.3 2 B 0.7404307 14, 15, 19, 158, 160
2UZO A X-ray 2.3 Monomer [C62]A:1297 0.1 14, 15, 19, 158, 160
2WEV A X-ray 2.3 2 B 1.0 14, 15, 19, 158, 160
1PXJ A X-ray 2.3 Monomer A 0.0 14, 15, 19, 158, 160
1PXP A X-ray 2.3 Monomer [CK8]A:500 0.1 14, 15, 19, 158, 160
2C6L A X-ray 2.3 Monomer A 0.0 14, 15, 19, 158, 160
2BPM A X-ray 2.4 2 B 0.6814263 14, 15, 19, 158, 160
3F5X A X-ray 2.4 8 B 0.7929441 14, 15, 19, 158, 160
1OKV A X-ray 2.4 3 B 1.0 14, 15, 19, 158, 160
2A4L A X-ray 2.4 Monomer [RRC]A:300 0.1 14, 15, 19, 158, 160
3LFS A X-ray 2.4 Monomer [A07]A:299 0.1 14, 15, 19, 158, 160
4EZ7 A X-ray 2.49 Monomer A 0.0 14, 15, 19, 158, 160
1PXL A X-ray 2.5 Monomer A 0.0 14, 15, 19, 158, 160
1F5Q A X-ray 2.5 2 B 1.0 14, 15, 19, 158, 160
2WIH A X-ray 2.5 2 B 0.90820044 14, 15, 19, 158, 160
1OKW A X-ray 2.5 3 B 1.0 14, 15, 19, 158, 160
1PXN A X-ray 2.5 Monomer A 0.0 14, 15, 19, 158, 160
1PF8 A X-ray 2.51 Monomer A 0.0 14, 15, 19, 158, 160
2WPA A X-ray 2.51 2 B 0.60435647 14, 15, 19, 158, 160
1PXM A X-ray 2.53 Monomer A 0.0 14, 15, 19, 158, 160
2WFY A X-ray 2.53 3 B 1.0 14, 15, 19, 158, 160
1OL2 A X-ray 2.6 3 B 1.0 14, 15, 19, 158, 160
1URC A X-ray 2.6 3 B 1.0 14, 15, 19, 158, 160
1BUH A X-ray 2.6 2 B 1.0 14, 15, 19, 158, 160
2BKZ A X-ray 2.6 2 B 0.57698447 14, 15, 19, 158, 160
2WXV A X-ray 2.6 2 B 1.0 14, 15, 19, 158, 160
5IF1 A X-ray 2.61 2 B 1.0 14, 15, 19, 158, 160
2C4G A X-ray 2.7 4 B 0.721785 14, 15, 19, 158, 160
5UQ2 A X-ray 2.7 4 B 1.0 14, 15, 19, 158, 160
4FX3 A X-ray 2.75 2 B 0.89028925 14, 15, 19, 158, 160
2X1N A X-ray 2.75 5 B 0.9962957 14, 15, 19, 158, 160
1FVV A X-ray 2.8 2 B 0.9243988 14, 15, 19, 158, 160
1PXK A X-ray 2.8 Monomer A 0.0 14, 15, 19, 158, 160
2C5V A X-ray 2.9 3 B 1.0 14, 15, 19, 158, 160
2C5X A X-ray 2.9 2 B 1.0 14, 15, 19, 158, 160
2WHB A X-ray 2.9 3 B 1.0 14, 15, 19, 158, 160
1OL1 A X-ray 2.9 3 B 1.0 14, 15, 19, 158, 160
3EID A X-ray 3.15 2 B 1.0 14, 15, 19, 158, 160
5UQ1 A X-ray 3.2 2 B 1.0 14, 15, 19, 158, 160
3EOC A X-ray 3.2 2 B 0.84396785 14, 15, 19, 158, 160
3EJ1 A X-ray 3.22 2 B 1.0 14, 15, 19, 158, 160
3RM6 A X-ray 1.6 Monomer [18Z]A:478 0.12975682 14, 19, 158, 160
4EOJ A X-ray 1.65 2 B 0.8932804 14, 15, 19, 158
2CCH A X-ray 1.7 3 B 0.87671894 14, 15, 19, 158
3DDQ A X-ray 1.8 2 B 0.67206866 14, 15, 19, 158
3R8Z A X-ray 1.85 Monomer [Z63]A:440 0.1 14, 15, 19, 160
1H0V A X-ray 1.9 Monomer A 0.0 14, 15, 19, 158
3QHW A X-ray 1.91 4 B 0.38997146 14, 15, 19, 158
4EOP A X-ray 1.99 2 B 0.8699782 14, 15, 19, 158
2IW9 A X-ray 2.0 2 B 0.6332711 14, 15, 19, 158
1H1R A X-ray 2.0 2 B 0.84126246 14, 15, 19, 158
1OIU A X-ray 2.0 2 B 0.82536054 14, 15, 19, 158
1H1S A X-ray 2.0 2 B 0.83814055 14, 15, 19, 158
4EOI A X-ray 2.0 2 B 0.9475716 14, 15, 19, 158
3TNW A X-ray 2.0 2 B 1.0 14, 15, 19, 158
4CFV A X-ray 2.0 2 B 0.6245283 14, 15, 19, 158
3BHT A X-ray 2.0 2 B 0.7506417 14, 15, 19, 158
5CYI A X-ray 2.0 2 B 1.0 14, 15, 19, 158
4BCO A X-ray 2.05 2 B 0.43120587 14, 15, 19, 158
4I3Z A X-ray 2.05 4 B 0.3292064 14, 15, 19, 158
4BCK A X-ray 2.05 2 B 1.0 14, 15, 19, 158
4BCN A X-ray 2.1 4 B 0.4619598 14, 15, 19, 158
1H1P A X-ray 2.1 2 B 0.9819744 14, 15, 19, 158
4EOM A X-ray 2.1 2 B 0.65717906 14, 15, 19, 158
4EOO A X-ray 2.1 2 B 0.5836941 14, 15, 19, 158
3MY5 A X-ray 2.1 2 B 0.70805633 14, 15, 19, 158
3BHV A X-ray 2.1 2 B 0.82993233 14, 15, 19, 158
1OI9 A X-ray 2.1 2 B 0.796097 14, 15, 19, 158
1W98 A X-ray 2.15 2 B 1.0 14, 15, 19, 158
4EOQ A X-ray 2.15 2 B 0.7852799 14, 15, 19, 158
1Y91 A X-ray 2.15 Monomer A 0.0 14, 15, 19, 160
4II5 A X-ray 2.15 4 B 0.4915156 14, 15, 19, 158
3QHR A X-ray 2.17 6 B 0.30440643 14, 15, 19, 158
4CFN A X-ray 2.2 2 B 0.9234173 14, 15, 19, 158
4EOR A X-ray 2.2 2 B 0.85224134 14, 15, 19, 158
4CFU A X-ray 2.2 2 B 0.74923426 14, 15, 19, 158
1H27 A X-ray 2.2 3 B 1.0 14, 15, 19, 158
1QMZ A X-ray 2.2 3 B 0.6291708 14, 15, 19, 158
1P5E A X-ray 2.22 2 B 1.0 14, 15, 19, 158
1H26 A X-ray 2.24 3 B 1.0 14, 15, 19, 158
4BCP A X-ray 2.26 2 B 0.504259 14, 15, 19, 158
2IW6 A X-ray 2.3 2 B 0.7345285 14, 15, 19, 158
1PKD A X-ray 2.3 2 B 0.96350676 14, 15, 19, 158
1JSU A X-ray 2.3 3 C 0.70160586 14, 15, 19, 158
3BHU A X-ray 2.3 2 B 0.7868888 14, 15, 19, 158
2IW8 A X-ray 2.3 2 B 0.76774114 14, 15, 19, 158
2UZL A X-ray 2.4 2 B 1.0 14, 15, 19, 158
2UZE A X-ray 2.4 2 B 1.0 14, 15, 19, 158
4EOL A X-ray 2.4 2 B 0.8977048 14, 15, 19, 158
4EON A X-ray 2.4 2 B 0.76001835 14, 15, 19, 158
1OIY A X-ray 2.4 2 B 0.84014004 14, 15, 19, 158
4CFW A X-ray 2.45 2 B 0.9162535 14, 15, 19, 158
4BCM A X-ray 2.45 2 B 0.6162903 14, 15, 19, 158
1H1Q A X-ray 2.5 2 B 0.96613294 14, 15, 19, 158
1H24 A X-ray 2.5 3 B 1.0 14, 15, 19, 158
1E9H A X-ray 2.5 2 B 0.81848973 14, 15, 19, 158
2G9X A X-ray 2.5 2 B 0.8752072 14, 15, 19, 158
1H25 A X-ray 2.5 3 B 1.0 14, 15, 19, 158
4EOS A X-ray 2.57 2 B 0.9854642 14, 15, 19, 158
4EOK A X-ray 2.57 2 B 0.7985391 14, 15, 19, 158
1OGU A X-ray 2.6 2 B 0.86447036 14, 15, 19, 158
2WMB A X-ray 2.6 3 B 1.0 14, 15, 19, 158
1JST A X-ray 2.6 2 B 0.72072065 14, 15, 19, 158
2C6T A X-ray 2.61 2 B 1.0 14, 15, 19, 158
2UZB A X-ray 2.7 2 B 0.99939394 14, 15, 19, 158
2CCI A X-ray 2.7 3 B 0.63176864 14, 15, 19, 158
1GY3 A X-ray 2.7 3 B 0.54021674 14, 15, 19, 158
3DDP A X-ray 2.7 2 B 1.0 14, 15, 19, 158
3DOG A X-ray 2.7 2 B 0.9362178 14, 15, 19, 158
2UZD A X-ray 2.72 2 B 1.0 14, 15, 19, 158
2I40 A X-ray 2.8 2 B 0.7742445 14, 15, 19, 158
5L2W A X-ray 2.8 4 B 0.8199477 14, 15, 19, 158
2WMA A X-ray 2.8 3 B 1.0 14, 15, 19, 158
1H28 A X-ray 2.8 3 B 1.0 14, 15, 19, 158
4CFM A X-ray 2.85 2 B 0.8738825 14, 15, 19, 158
2JGZ A X-ray 2.9 4 B 1.0 14, 15, 19, 158
5NEV A X-ray 2.97 2 B 1.0 14, 15, 19, 158
1FQ1 B X-ray 3.0 2 A 0.5090257 14, 15, 19, 158
4CFX A X-ray 3.5 2 B 0.9098318 14, 15, 19, 158
4EK6 A X-ray 1.52 Monomer [ACE]A:0 0.07457554 14, 15, 19
1JVP P X-ray 1.53 Monomer P 0.0 14, 15, 19
4FKS A X-ray 1.55 Monomer [46K]A:301 0.050869346 14, 15, 19
1OIT A X-ray 1.6 Monomer A 0.0 14, 15, 19
5ANJ A X-ray 1.6 Monomer [ZXC]A:1299 0.1 14, 15, 19
4FKP A X-ray 1.6 Monomer [NA]A:302 0.09478445 14, 15, 19
5K4J A X-ray 1.6 Monomer [6QB]A:301 0.1 14, 15, 19
4FKT A X-ray 1.6 Monomer A 0.0 14, 15, 19
4FKJ A X-ray 1.63 Monomer [11K]A:301 0.07863985 14, 15, 19
2R3N A X-ray 1.63 Monomer [SCZ]A:501 0.06928883 14, 15, 19
4ACM A X-ray 1.63 Monomer [7YG]A:1302 0.041587237 14, 15, 19
2R3L A X-ray 1.65 Monomer [SCW]A:501 0.065779045 14, 15, 19
2R3J A X-ray 1.65 Monomer [SCJ]A:501 0.069130756 14, 15, 19
5IEY A X-ray 1.66 Monomer [6AE]A:1001 0.1 14, 15, 19
2VTT A X-ray 1.68 Monomer [LZD]A:1299 0.1 14, 15, 19
3SW4 A X-ray 1.7 Monomer [ACE]A:0 0.22879104 14, 15, 19
4FKV A X-ray 1.7 Monomer [61K]A:301 0.07173042 14, 15, 19
4EK8 A X-ray 1.7 Monomer [ACE]A:0 0.19228785 14, 15, 19
2R3K A X-ray 1.7 Monomer [SCQ]A:501 0.062749416 14, 15, 19
5ANO A X-ray 1.7 Monomer A 0.0 14, 15, 19
2R3M A X-ray 1.7 Monomer [ACE]A:0 0.05618031 14, 15, 19
4FKQ A X-ray 1.75 Monomer [42K]A:301 0.06804381 14, 15, 19
3R9N A X-ray 1.75 Monomer [Z68]A:529 0.1 14, 15, 19
3RAH A X-ray 1.75 Monomer A 0.0 14, 15, 19
3S1H A X-ray 1.75 Monomer A 0.0 14, 15, 19
3RMF A X-ray 1.75 Monomer [20Z]A:496 0.1 14, 15, 19
3RAL A X-ray 1.75 Monomer A 0.0 14, 15, 19
3R7U A X-ray 1.75 Monomer A 0.0 14, 15, 19
3RAK A X-ray 1.75 Monomer A 0.0 14, 15, 19
3RPR A X-ray 1.75 Monomer A 0.0 14, 15, 19
4FKW A X-ray 1.8 Monomer [62K]A:301 0.0736613 14, 15, 19
1H08 A X-ray 1.8 Monomer [ACE]A:0 0.03864468 14, 15, 19
3IG7 A X-ray 1.8 Monomer [EFP]A:999 0.06894429 14, 15, 19
3SW7 A X-ray 1.8 Monomer A 0.0 14, 15, 19
3R8M A X-ray 1.8 Monomer [PO4]A:485 0.09774998 14, 15, 19
5FP6 A X-ray 1.85 Monomer [MFZ]A:1296 0.05194643 14, 15, 19
3QTR A X-ray 1.85 Monomer A 0.0 14, 15, 19
3R7I A X-ray 1.85 Monomer A 0.0 14, 15, 19
2BTR A X-ray 1.85 Monomer A 0.0 14, 15, 19
2B55 A X-ray 1.85 Monomer [D31]A:299 0.1 14, 15, 19
4NJ3 A X-ray 1.85 Monomer [2KD]A:301 0.09270403 14, 15, 19
2B52 A X-ray 1.88 Monomer [D42]A:299 0.1 14, 15, 19
3RZB A X-ray 1.9 Monomer [02Z]A:458 0.1 14, 15, 19
2BHE A X-ray 1.9 Monomer [BRY]A:1299 0.1 14, 15, 19
5ANK A X-ray 1.9 Monomer [RJI]A:1299 0.1 14, 15, 19
3FZ1 A X-ray 1.9 Monomer A 0.0 14, 15, 19
2W05 A X-ray 1.9 Monomer [FRT]A:1299 0.1 14, 15, 19
5ANI A X-ray 1.9 Monomer [ES4]A:1299 0.1 14, 15, 19
3QTS A X-ray 1.9 Monomer A 0.0 14, 15, 19
2VTS A X-ray 1.9 Monomer A 0.0 14, 15, 19
3EZR A X-ray 1.9 Monomer [EZR]A:301 0.15608534 14, 15, 19
3R9O A X-ray 1.9 Monomer [Z71]A:401 0.1 14, 15, 19
3RPY A X-ray 1.9 Monomer [27Z]A:470 0.1 14, 15, 19
4FKR A X-ray 1.9 Monomer [45K]A:301 0.07457468 14, 15, 19
2VTQ A X-ray 1.9 Monomer [LZA]A:1299 0.1 14, 15, 19
2VV9 A X-ray 1.9 Monomer A 0.0 14, 15, 19
2VTH A X-ray 1.9 Monomer [GOL]A:1299 0.058963582 14, 15, 19
5JQ8 A X-ray 1.94 Monomer [I73]A:301 0.1 14, 15, 19
4BGH A X-ray 1.95 Monomer A 0.0 14, 15, 19
3PJ8 A X-ray 1.96 Monomer [404]A:299 0.1 14, 15, 19
3EZV A X-ray 1.99 Monomer [EZV]A:300 0.1 14, 15, 19
2BTS A X-ray 1.99 Monomer A 0.0 14, 15, 19
2VTA A X-ray 2.0 Monomer A 0.0 14, 15, 19
3WBL A X-ray 2.0 Monomer [PDY]A:302 0.073042706 14, 15, 19
1KE7 A X-ray 2.0 Monomer [LS3]A:299 0.1 14, 15, 19
1KE8 A X-ray 2.0 Monomer [LS4]A:299 0.1 14, 15, 19
5A14 A X-ray 2.0 Monomer [LQ5]A:1297 0.058356475 14, 15, 19
1GII A X-ray 2.0 Monomer [1PU]A:501 0.1 14, 15, 19
1KE9 A X-ray 2.0 Monomer A 0.0 14, 15, 19
1KE6 A X-ray 2.0 Monomer [LS2]A:299 0.1 14, 15, 19
1AQ1 A X-ray 2.0 Monomer [STU]A:299 0.1 14, 15, 19
2VTI A X-ray 2.0 Monomer A 0.0 14, 15, 19
3ULI A X-ray 2.0 Monomer A 0.0 14, 15, 19
1R78 A X-ray 2.0 Monomer [FMD]A:299 0.1 14, 15, 19
4LYN A X-ray 2.0 Monomer [1YG]A:301 0.1 14, 15, 19
5IEX A X-ray 2.03 Monomer [6AF]A:1001 0.1 14, 15, 19
5IEV A X-ray 2.03 Monomer A 0.0 14, 15, 19
2W06 A X-ray 2.04 Monomer [FRV]A:1300 0.07129253 14, 15, 19
1CKP A X-ray 2.05 Monomer A 0.0 14, 15, 19
1H0W A X-ray 2.1 Monomer A 0.0 14, 15, 19
4D1X A X-ray 2.1 Monomer A 0.0 14, 15, 19
1DM2 A X-ray 2.1 Monomer A 0.0 14, 15, 19
2W1H A X-ray 2.15 Monomer A 0.0 14, 15, 19
2VTP A X-ray 2.15 Monomer [LZ9]A:1299 0.1 14, 15, 19
2W17 A X-ray 2.15 Monomer A 0.0 14, 15, 19
2VTO A X-ray 2.19 Monomer [LZ8]A:1299 0.1 14, 15, 19
2VTJ A X-ray 2.2 Monomer [LZ4]A:1300 0.08686123 14, 15, 19
1KE5 A X-ray 2.2 Monomer A 0.0 14, 15, 19
2DUV A X-ray 2.2 Monomer [371]A:501 0.1 14, 15, 19
1FVT A X-ray 2.2 Monomer A 0.0 14, 15, 19
1WCC A X-ray 2.2 Monomer [CIG]A:1299 0.1 14, 15, 19
1DI8 A X-ray 2.2 Monomer [DTQ]A:500 0.1 14, 15, 19
1GIJ A X-ray 2.2 Monomer [2PU]A:501 0.1 14, 15, 19
1W0X C X-ray 2.2 Monomer C 0.0 14, 15, 19
2VTN A X-ray 2.2 Monomer A 0.0 14, 15, 19
1VYZ A X-ray 2.21 Monomer A 0.0 14, 15, 19
3LFN A X-ray 2.28 Monomer [A27]A:299 0.1 14, 15, 19
3S2P A X-ray 2.3 Monomer A 0.0 14, 15, 19
2UZN A X-ray 2.3 Monomer [C96]A:1299 0.1 14, 15, 19
2CJM A X-ray 2.3 2 B 0.8649823 14, 19, 158
5AND A X-ray 2.3 Monomer A 0.0 14, 15, 19
2R64 A X-ray 2.3 Monomer A 0.0 14, 15, 19
1V1K A X-ray 2.31 Monomer A 0.0 14, 15, 19
2J9M A X-ray 2.5 Monomer A 0.0 14, 15, 19
2BHH A X-ray 2.6 Monomer A 0.0 14, 15, 19
1G5S A X-ray 2.61 Monomer [I17]A:400 0.1 14, 15, 19
2WIP A X-ray 2.8 2 B 0.9425696 19, 158, 160
1GIH A X-ray 2.8 Monomer [1PU]A:501 0.1 14, 15, 19
5UQ3 A X-ray 3.6 6 C 1.0 19, 158, 160
1H00 A X-ray 1.6 Monomer A 0.0 15, 19
1URW A X-ray 1.6 Monomer [I1P]A:1300 0.06047665 15, 19
5D1J A X-ray 1.8 Monomer A 0.0 15, 19
4BZD A X-ray 1.83 Monomer A 0.0 15, 19
5FP5 A X-ray 2.16 Monomer [ACE]A:1296 0.1 15, 19
4BCQ A X-ray 2.4 2 B 0.7062276 19, 158
4D1Z A X-ray 1.85 Monomer A 0.0 19
5ANG A X-ray 1.9 Monomer [WY3]A:1299 0.1 19
1PYE A X-ray 2.0 Monomer [PM1]A:700 0.1 19
1OIQ A X-ray 2.31 Monomer A 0.0 19
1P2A A X-ray 2.5 Monomer [5BN]A:301 0.1 19

Mutations

Showing 4 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
15 Y S Polymorphism
18 V L Polymorphism
45 P L Unclassified A glioblastoma multiforme sample
290 T S Polymorphism