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CTRO_HUMAN : Citron Rho-interacting kinase

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PDB 
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Phospho-sites

Showing 19 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
371 SER PRIDE yes
433 SER UP, PRIDE Combined yes
436 SER PRIDE yes
440 SER UP, PRIDE Combined yes
480 SER UP, PRIDE Combined yes
582 SER UP, PRIDE Combined yes
1048 SER PRIDE yes
1306 THR PRIDE yes
1317 SER PRIDE yes
1345 THR PRIDE yes
1432 SER PRIDE yes
1582 SER PRIDE yes
1929 TYR PRIDE yes
1940 SER UP, PRIDE Combined yes
1955 THR PRIDE yes
1971 SER PRIDE yes
1993 SER UP, PRIDE Combined yes
2013 THR UP, PRIDE Combined yes
2026 SER PRIDE yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 27 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
IDWNNIRNSPPPFVPTLK 371 363 380 9 1
ALGILGRSESVVSGLDSPAK 433 424 443 10 1
SESVVSGLDSPAK 433 431 443 3 2
SESVVSGLDSPAK 436 431 443 6 1
SESVVSGLDSPAK 440 431 443 10 11
RVSEVEAVLSQK 480 478 489 3 3
RRSDLYESELR 582 580 590 3 3
ERQWEAWRSVLGDEK 1048 1040 1054 9 1
ATDHPHPSTPATAR 1306 1298 1311 9 2
QQIAMSAIVRSPEHQPSAMSLLAPPSSR 1317 1312 1339 6 1
ESSTPEEFSR 1345 1342 1351 4 2
DKMNSPGLQTK 1432 1428 1438 5 2
MNSPGLQTK 1432 1430 1438 3 4
LLGNSLLK 1582 1578 1585 5 2
RGPPTYNEHITK 1929 1924 1935 6 1
RVASSPAPPEGPSHPR 1940 1936 1951 5 4
RVASSPAPPEGPSHPREPSTPHR 1940 1936 1958 5 3
VASSPAPPEGPSHPR 1940 1937 1951 4 5
VASSPAPPEGPSHPREPSTPHR 1955 1937 1958 19 1
DKSPGRPLER 1971 1969 1978 3 11
SPGRPLER 1971 1971 1978 1 2
ERSPGRLFEDSSR 1993 1991 2003 3 10
SPGRLFEDSSR 1993 1993 2003 1 1
GRLPAGAVRTPLSQVNK 2013 2004 2020 10 3
LPAGAVRTPLSQVNK 2013 2006 2020 8 1
TPLSQVNK 2013 2013 2020 1 1
TPLSQVNKVWDQSSV 2026 2013 2027 14 1

Structures

Showing 0 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure

Mutations

Showing 6 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
7 G E Polymorphism
9 R Q Polymorphism
106 G V Disease Microcephaly 17, primary, autosomal recessive (MCPH17) [MIM:617090]
126 K Q Disease Microcephaly 17, primary, autosomal recessive (MCPH17) [MIM:617090]
183 L F Polymorphism
230 D V Disease Microcephaly 17, primary, autosomal recessive (MCPH17) [MIM:617090]