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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 5 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
92 SER PRIDE yes
183 SER UP, PRIDE Combined yes
190 SER PRIDE yes
273 SER PRIDE yes
292 SER UP, PRIDE Combined yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 8 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
92 83 95 10 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
92 84 95 9 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 4 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001374 1 Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling Homo sapiens (Human) PARTIAL 2015-08-24 HeLa cell
92 85 95 8 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 76 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001333 3 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell
PXD002286 3 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 - -
183 177 189 7 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD006482 1 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney -
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
190 182 191 9 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003531 1 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell
273 269 293 5 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001374 7 Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling Homo sapiens (Human) PARTIAL 2015-08-24 HeLa cell
273 273 293 1 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001374 1 Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling Homo sapiens (Human) PARTIAL 2015-08-24 HeLa cell -
PXD000680 4 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
292 276 293 17 4
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 1 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell -
PXD006482 2 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney
PXD005366 22 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture -
PXD000680 2 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -

Structures

Showing 1 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
4BS2 A NMR Monomer B 0.0 183, 190
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
183 183 SER C 1.0 98.0693359375 0.0
190 190 SER C 1.0 22.415494918823242 0.0

Mutations

Showing 21 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
90 A V Polymorphism
169 D G Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
267 N S Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
287 G S Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
290 G A Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
294 G V Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
295 G S Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
298 G S Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
315 A T Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
331 Q K Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
332 S N Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
335 G D Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
337 M V Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
343 Q R Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
348 G C Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
357 G R Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
361 R T Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
379 S P Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
382 A T Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
390 N S Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]
393 S L Disease Amyotrophic lateral sclerosis 10 (ALS10) [MIM:612069]