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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 5 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
60 TYR PRIDE yes
80 SER PRIDE yes
131 SER UP Similarity
284 SER PRIDE yes
395 TYR PRIDE yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 4 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
60 48 72 13 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
80 73 84 8 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 8 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
PXD004452 2 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
284 266 287 19 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 2 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
395 394 399 2 5
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003531 2 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD006482 2 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney -
PXD005366 1 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture -
PXD004452 8 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
PXD003198 1 Characterisation of pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling Homo sapiens (Human) PARTIAL 2016-06-09 pancreatic cell line

Structures

Showing 3 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
3CB2 A X-ray 2.299999952316284 2 [GDP]A:500 0.5382845 60, 80, 131, 284, 395
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
60 60 TYR E 1.0 34.83987045288086 0.0
80 80 SER C 1.0 25.31124496459961 0.0
131 131 SER C 1.0 62.049072265625 0.0
284 284 SER C 1.0 139.40606689453125 0.0
395 395 TYR H 0.78 6.584929466247559 0.0
1Z5V A X-ray 2.7100000381469727 Monomer [GSP]A:2466 0.052519035 60, 80, 131, 284, 395
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
60 60 TYR E 1.0 48.5043830871582 0.0
80 80 SER C 1.0 31.495500564575195 0.0
131 131 SER C 1.0 43.68832778930664 0.0
284 284 SER C 1.0 129.4560546875 0.0
395 395 TYR H 0.78 5.831170082092285 0.0
1Z5W A X-ray 3.0 Monomer [GTP]A:2466 0.04431984 60, 80, 131, 284, 395
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
60 60 TYR E 1.0 50.70269012451172 0.0
80 80 SER C 1.0 28.364547729492188 0.0
131 131 SER C 1.0 42.84952163696289 0.0
284 284 SER C 1.0 147.718994140625 0.0
395 395 TYR H 0.78 5.11207914352417 0.0

Mutations

Showing 4 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
92 Y C Disease Cortical dysplasia, complex, with other brain malformations 4 (CDCBM4) [MIM:615412]
331 T P Disease Cortical dysplasia, complex, with other brain malformations 4 (CDCBM4) [MIM:615412]
387 L P Disease Cortical dysplasia, complex, with other brain malformations 4 (CDCBM4) [MIM:615412]
413 M V Polymorphism