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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 11 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
2 THR UP Combined
39 SER PRIDE yes
47 SER PRIDE yes
50 TYR PRIDE yes
60 SER UP Similarity
130 TYR PRIDE yes
186 SER UP Similarity
212 SER PRIDE yes
213 TYR PRIDE yes
217 THR PRIDE yes
232 SER UP Combined

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 7 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
39 30 43 10 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
47 44 51 4 10
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 5 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell -
PXD000612 50 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004940 1 Performance of the Orbitrap Fusion Lumos Tribrid in single-shot analyses of human samples Homo sapiens (Human) PARTIAL 2017-03-09 HeLa cell -
PXD003531 22 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD002286 66 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 - -
PXD006482 5 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney -
PXD005366 5 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture
PXD001550 14 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD004452 5 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
PXD000680 2 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -
50 44 51 7 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001565 2 Evaluation of phospho-tyrosine antibodies for label-free phosphoproteomics Homo sapiens (Human) PARTIAL 2015-12-09 colon,brain
130 130 140 1 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD002286 1 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 -
212 196 214 17 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
213 196 214 18 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003198 2 Characterisation of pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling Homo sapiens (Human) PARTIAL 2016-06-09 pancreatic cell line
217 215 224 3 4
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD003531 1 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD002286 4 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 -
PXD004452 10 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -

Structures

Showing 5 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
4DNK A X-ray 2.200000047683716 2 [PO4]A:301 0.79216063 2, 39, 47, 50, 60, 130, 186, 212, 213, 217, 232
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
2 2 THR C 0.4 191.59410095214844 0.0
39 39 SER C 1.0 53.7313232421875 0.0
47 47 SER H 1.0 27.887165069580078 0.0
50 50 TYR H 1.0 9.102119445800781 0.0
60 60 SER H 1.0 45.53328323364258 0.0
130 130 TYR H 1.0 27.630319595336914 0.0
186 186 SER C 1.0 12.090476036071777 0.0
212 212 SER C 1.0 20.298776626586914 0.0
213 213 TYR H 1.0 100.06806945800781 0.0
217 217 THR H 1.0 39.24385452270508 0.0
231 231 THR H 1.0 97.93775939941406 0.0
232 232 SER H 1.0 86.78888702392578 0.0
5N10 A X-ray 1.600000023841858 5 B 0.9281535 39, 47, 50, 60, 130, 186, 212, 213, 217, 232
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
39 39 SER C 1.0 53.6024169921875 0.0
47 47 SER H 1.0 27.633230209350586 0.0
50 50 TYR H 1.0 12.318177223205566 0.0
60 60 SER H 1.0 47.860408782958984 42.964805603027344
130 130 TYR H 1.0 13.182669639587402 0.0
186 186 SER C 1.0 27.958372116088867 0.0
212 212 SER C 1.0 25.399808883666992 0.0
213 213 TYR H 1.0 99.7061538696289 0.0
217 217 THR H 1.0 46.35127639770508 0.0
231 231 THR H 1.0 94.93064880371094 0.0
232 232 SER C 1.0 91.7948989868164 0.0
2BQ0 A X-ray 2.5 2 B 1.0 39, 47, 50, 60, 130, 186, 212, 213, 217, 232
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
39 39 SER C 1.0 49.28845977783203 0.0
47 47 SER H 1.0 28.344440460205078 0.0
50 50 TYR H 1.0 10.392986297607422 0.0
60 60 SER H 1.0 47.554141998291016 43.399803161621094
130 130 TYR H 1.0 22.907546997070312 0.0
186 186 SER C 1.0 17.636133193969727 0.0
212 212 SER C 1.0 27.0147705078125 0.0
213 213 TYR H 1.0 97.19163513183594 0.0
217 217 THR H 1.0 43.77166748046875 0.0
231 231 THR H 1.0 103.29012298583984 0.0
232 232 SER C 1.0 129.39620971679688 0.0
2C23 A X-ray 2.6500000953674316 4 A 1.0 39, 47, 50, 60, 130, 186, 212, 213, 217, 232
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
39 39 SER C 1.0 56.255104064941406 0.0
47 47 SER H 1.0 21.606203079223633 0.0
50 50 TYR H 1.0 9.185907363891602 0.0
60 60 SER H 1.0 49.622901916503906 42.79197692871094
130 130 TYR H 1.0 29.001506805419922 0.0
186 186 SER C 1.0 31.543216705322266 0.0
212 212 SER H 1.0 31.471651077270508 0.0
213 213 TYR H 1.0 121.00240325927734 0.0
217 217 THR H 1.0 41.19315719604492 0.0
231 231 THR C 1.0 107.39945983886719 0.0
232 232 SER C 1.0 128.94923400878906 0.0
6BYK A X-ray 3.0 2 B 1.0 39, 47, 50, 60, 130, 186, 212, 213, 217, 232
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
39 39 SER C 1.0 54.56871795654297 0.0
47 47 SER H 1.0 30.480623245239258 0.0
50 50 TYR H 1.0 13.19864273071289 0.0
60 60 SER H 1.0 46.19865417480469 37.50981521606445
130 130 TYR H 1.0 20.715635299682617 0.0
186 186 SER C 1.0 23.880239486694336 0.0
212 212 SER H 1.0 55.86396408081055 0.0
213 213 TYR H 1.0 85.83843231201172 0.0
217 217 THR H 1.0 38.754207611083984 0.0
231 231 THR H 1.0 95.7535400390625 0.0
232 232 SER C 1.0 123.1702880859375 0.0

Mutations

Showing 1 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
99 V I Unclassified