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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 12 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
6 SER PRIDE yes
168 SER PRIDE yes
364 SER UP, PRIDE Combined yes
370 THR PRIDE yes
505 SER PRIDE yes
511 SER PRIDE
515 SER PRIDE
522 SER PRIDE yes
590 SER PRIDE
593 SER PRIDE
609 SER PRIDE yes
709 THR PRIDE yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 15 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
6 2 13 5 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003531 13 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell
6 5 13 2 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003531 5 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell
168 158 185 11 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
364 359 381 6 11
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004252 10 Modulating the selectivity of affinity absorbents to multi-phosphopeptides by a novel competitive substitution strategy Homo sapiens (Human) PARTIAL 2016-08-03 cell culture -
PXD000612 110 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004415 1 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte -
PXD001546 27 Reproducibility of label-free single-shot phosphoproteomics applied to CRC cell lines Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD003531 6 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD004940 1 Performance of the Orbitrap Fusion Lumos Tribrid in single-shot analyses of human samples Homo sapiens (Human) PARTIAL 2017-03-09 HeLa cell -
PXD002286 120 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 - -
PXD005366 55 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture -
PXD001550 46 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture
PXD004452 46 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
PXD000680 19 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -
370 359 381 12 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD002286 8 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 -
PXD000680 2 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -
505 492 510 14 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 6 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
PXD006482 1 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney -
PXD004452 4 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
505 498 510 8 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 8 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
511 504 535 8 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 21 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004452 15 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
511 511 535 1 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 63 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004452 9 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
515 511 535 5 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 2 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
522 511 535 12 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
590 587 603 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
593 587 603 7 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
609 604 610 6 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001333 1 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell
709 692 713 18 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD002286 2 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 - -
PXD004452 2 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon

Structures

Showing 16 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
5M7R A X-ray 2.3499999046325684 2 B 1.0 168, 590, 593, 609, 709
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 7.368216514587402 0.0
374 374 TYR C NaN 13.160347938537598 0.0
590 590 SER H NaN 74.5755386352539 0.0
593 593 SER C NaN 29.677907943725586 0.0
609 609 SER H NaN 59.33244705200195 0.0
709 709 THR C NaN 61.002933502197266 0.0
5M7U A X-ray 2.299999952316284 2 B 1.0 168, 590, 593, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 0.24629829823970795 0.0
374 374 TYR C NaN 12.834656715393066 0.0
590 590 SER H NaN 93.18128967285156 0.0
593 593 SER C NaN 153.079833984375 0.0
609 609 SER H NaN 71.4904556274414 0.0
5M7S A X-ray 2.4000000953674316 2 B 1.0 168, 590, 593, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 0.49093082547187805 0.0
374 374 TYR C NaN 34.42420959472656 0.0
590 590 SER H NaN 99.12329864501953 0.0
593 593 SER C NaN 152.4139862060547 0.0
609 609 SER H NaN 55.671810150146484 0.0
5VVO A X-ray 2.5999999046325684 2 B 1.0 168, 590, 593, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 4.1004438400268555 0.0
374 374 TYR C NaN 40.95217514038086 0.0
590 590 SER C NaN 54.871726989746094 0.0
593 593 SER C NaN 110.03172302246094 0.0
609 609 SER H NaN 67.37706756591797 0.0
5M7T A X-ray 2.5999999046325684 2 B 0.86810356 168, 590, 593, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 5.162685394287109 0.0
374 374 TYR C NaN 19.391948699951172 0.0
590 590 SER H NaN 78.83853149414062 0.0
593 593 SER C NaN 65.31047058105469 0.0
609 609 SER H NaN 67.19477844238281 0.0
5UN8 A X-ray 2.130000114440918 4 C 1.0 168, 590, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 5.4170026779174805 0.0
374 374 TYR C NaN 99.90251159667969 0.0
590 590 SER H NaN 110.15426635742188 0.0
609 609 SER H NaN 54.496177673339844 0.0
5UN9 A X-ray 2.5 2 B 1.0 168, 590, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 4.081236362457275 0.0
374 374 TYR C NaN 101.50878143310547 0.0
590 590 SER H NaN 111.57423400878906 0.0
609 609 SER H NaN 69.32148742675781 0.0
5VVU A X-ray 2.700000047683716 4 C 1.0 168, 590, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 3.630507230758667 0.0
374 374 TYR C NaN 99.58375549316406 0.0
590 590 SER H NaN 105.7070541381836 0.0
609 609 SER H NaN 64.12881469726562 0.0
5VVV A X-ray 2.799999952316284 4 C 1.0 168, 590, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 5.644124507904053 0.0
374 374 TYR C NaN 99.27132415771484 0.0
590 590 SER H NaN 99.96475982666016 0.0
609 609 SER H NaN 77.66668701171875 0.0
5VVX A X-ray 2.9000000953674316 4 C 1.0 168, 590, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 4.112993240356445 0.0
374 374 TYR C NaN 98.99848937988281 0.0
590 590 SER H NaN 102.9179458618164 0.0
609 609 SER H NaN 60.72810745239258 0.0
5UHK A X-ray 2.9700000286102295 4 B 0.9485177 168, 590, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 1.9642422199249268 0.0
374 374 TYR C NaN 22.605621337890625 0.0
590 590 SER C NaN 145.78269958496094 0.0
609 609 SER H NaN 67.9290542602539 0.0
5UHL B X-ray 3.140000104904175 4 A 1.0 168, 590, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER C NaN 7.362000465393066 0.0
374 374 TYR C NaN 23.991086959838867 0.0
590 590 SER C NaN 148.49859619140625 0.0
609 609 SER H NaN 62.90984344482422 0.0
5UHO B X-ray 3.2100000381469727 4 D 1.0 168, 590, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 4.689630508422852 0.0
374 374 TYR C NaN 29.288320541381836 0.0
590 590 SER C NaN 141.27276611328125 0.0
609 609 SER H NaN 63.142982482910156 0.0
5TKE A X-ray 2.4800000190734863 2 B 1.0 168, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 3.956073522567749 0.0
374 374 TYR C NaN 42.490726470947266 0.0
609 609 SER H NaN 59.011287689208984 0.0
5UHP E X-ray 2.7899999618530273 2 H 1.0 168, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 8.044602394104004 0.0
374 374 TYR C NaN 18.77817726135254 0.0
609 609 SER H NaN 47.246360778808594 0.0
5VVT A X-ray 2.799999952316284 4 C 1.0 168, 609
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
168 168 SER E NaN 3.607759475708008 0.0
374 374 TYR C NaN 97.76355743408203 0.0
609 609 SER H NaN 72.06103515625 0.0

Mutations

Showing 2 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
46 G E Polymorphism
602 E K Polymorphism