Welcome to Scop3P

Search for the desired protein with Uniprot accession, protein name/keyword, ProteomeXchange ID or PDB id

Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

  • Zoom in and zoom out (both with mouse and buttons on the right top corner) to see modificationson the protein
  • Slide the chart to see other modifications (both with mouse and buttons on the right topcorner)
  • Hover on the modification to see more information and position on the structure.
PDB 
 AlphaFold
Phospho-sites

Showing 3 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
77 TYR PRIDE yes
92 THR PRIDE yes
295 SER PRIDE yes

3D structure is not available

Display Settings

Hover over to see the values, zoom (in/out) or drag by using the mouse pointer.

Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 3 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
77 74 85 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
92 86 96 7 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003660 7 Early Signaling Dynamics of EGFR Homo sapiens (Human) COMPLETE 2016-06-24 Epithelial cell, cell culture
295 262 297 34 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004415 1 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte

Structures

Showing 17 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
5FII A X-ray 1.7999999523162842 2 C 1.0 77, 92
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
77 77 TYR E 0.95 82.26810455322266 53.087257385253906
92 92 THR H 0.32 91.40248107910156 0.0
1J8U A X-ray 1.5 Monomer [FE2]A:428 0.07823878 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 14.200674057006836 0.0
1J8T A X-ray 1.7000000476837158 Monomer [FE2]A:428 0.1 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 13.736773490905762 0.0
1MMT A X-ray 2.0 Monomer [SO4]A:428 0.043543752 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 15.570930480957031 0.0
4PAH A X-ray 2.0 Monomer [FE]A:425 0.050820556 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 11.807112693786621 0.0
1MMK A X-ray 2.0 Monomer [SO4]A:429 0.04206279 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 14.940428733825684 0.0
1DMW A X-ray 2.0 Monomer [FE]A:425 0.077719994 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 13.378486633300781 0.0
1PAH A X-ray 2.0 Monomer [FE]A:425 0.1 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 12.626803398132324 0.0
3PAH A X-ray 2.0 Monomer [FE]A:425 0.080251016 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 13.48878002166748 0.0
1TDW A X-ray 2.0999999046325684 Monomer [FE]A:425 0.1 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 12.987600326538086 0.0
1LRM A X-ray 2.0999999046325684 Monomer [FE]A:428 0.07534009 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER H 0.96 13.731866836547852 0.0
5PAH A X-ray 2.0999999046325684 Monomer [FE]A:425 0.071685135 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER H 0.96 12.231112480163574 0.0
4ANP A X-ray 2.109999895095825 Monomer [3QI]A:1427 0.045208532 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 11.825846672058105 0.0
6PAH A X-ray 2.1500000953674316 Monomer [FE]A:425 0.1 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 14.479133605957031 0.0
1TG2 A X-ray 2.200000047683716 Monomer [FE]A:425 0.076268196 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 9.81718921661377 0.0
1KW0 A X-ray 2.5 Monomer [FE2]A:428 0.06632385 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 13.491850852966309 0.0
2PAH A X-ray 3.0999999046325684 4 [FE]A:453 0.58118373 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 14.570683479309082 0.0

Mutations

Showing 158 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
16 S P Disease Phenylketonuria (PKU) [MIM:261600]
20 Q L Disease Hyperphenylalaninemia (HPA) [MIM:261600]
39 F L Disease Hyperphenylalaninemia (HPA) [MIM:261600]
40 S L Disease Phenylketonuria (PKU) [MIM:261600]
41 L P Disease Phenylketonuria (PKU) [MIM:261600]
42 K I Disease Phenylketonuria (PKU) [MIM:261600]
45 V A Disease Phenylketonuria (PKU) [MIM:261600]
46 G S Disease Phenylketonuria (PKU) [MIM:261600]
47 A V Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
48 L S Disease Phenylketonuria (PKU) [MIM:261600]
53 R H Disease Phenylketonuria (PKU) [MIM:261600]
55 F L Disease Phenylketonuria (PKU) [MIM:261600]
56 E D Disease Phenylketonuria (PKU) [MIM:261600]
61 N D Disease Phenylketonuria (PKU) [MIM:261600]
62 L P Disease Phenylketonuria (PKU) [MIM:261600]
65 I T Disease Phenylketonuria (PKU) [MIM:261600]
67 S P Disease Phenylketonuria (PKU) [MIM:261600]
68 R S Disease Phenylketonuria (PKU) [MIM:261600]
76 E G Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
84 D Y Disease Phenylketonuria (PKU) [MIM:261600]
87 S R Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
92 T I Disease Phenylketonuria (PKU) [MIM:261600]
98 L S Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
104 A D Disease Phenylketonuria (PKU) [MIM:261600]
110 S C Disease Hyperphenylalaninemia (HPA) [MIM:261600]
121 F L Disease Hyperphenylalaninemia (HPA) [MIM:261600]
124 T I Disease Phenylketonuria (PKU) [MIM:261600]
129 D Y Disease Phenylketonuria (PKU) [MIM:261600]
143 D G Disease Phenylketonuria (PKU) [MIM:261600]
145 D V Disease Phenylketonuria (PKU) [MIM:261600]
146 H Y Disease Phenylketonuria (PKU) [MIM:261600]
148 G S Disease Phenylketonuria (PKU) [MIM:261600]
151 D H Disease Phenylketonuria (PKU) [MIM:261600]
154 Y N Disease Phenylketonuria (PKU) [MIM:261600]
155 R P Disease Phenylketonuria (PKU) [MIM:261600]
157 R S Disease Phenylketonuria (PKU) [MIM:261600]
158 R W Disease Phenylketonuria (PKU) [MIM:261600]
160 Q P Disease Phenylketonuria (PKU) [MIM:261600]
161 F S Disease Phenylketonuria (PKU) [MIM:261600]
164 I T Disease Phenylketonuria (PKU) [MIM:261600]
167 N I Disease Phenylketonuria (PKU) [MIM:261600]
169 R H Disease Phenylketonuria (PKU) [MIM:261600]
170 H D Disease Hyperphenylalaninemia (HPA) [MIM:261600]
171 G R Disease Phenylketonuria (PKU) [MIM:261600]
173 P T Disease Phenylketonuria (PKU) [MIM:261600]
174 I T Disease Phenylketonuria (PKU) [MIM:261600]
175 P A Disease Phenylketonuria (PKU) [MIM:261600]
176 R P Disease Phenylketonuria (PKU) [MIM:261600]
177 V M Disease Hyperphenylalaninemia (HPA) [MIM:261600]
178 E G Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
183 E Q Disease Phenylketonuria (PKU) [MIM:261600]
190 V A Disease Phenylketonuria (PKU) [MIM:261600]
194 L P Disease Phenylketonuria (PKU) [MIM:261600]
196 S Y Disease Hyperphenylalaninemia (HPA) [MIM:261600]
201 H R Disease Phenylketonuria (PKU) [MIM:261600]
204 Y C Disease Phenylketonuria (PKU) [MIM:261600]
205 E A Disease Phenylketonuria (PKU) [MIM:261600]
206 Y D Disease Phenylketonuria (PKU) [MIM:261600]
207 N D Disease Phenylketonuria (PKU) [MIM:261600]
211 P T Disease Phenylketonuria (PKU) [MIM:261600]
212 L P Disease Phenylketonuria (PKU) [MIM:261600]
213 L P Disease Phenylketonuria (PKU) [MIM:261600]
217 C G Disease Phenylketonuria (PKU) [MIM:261600]
218 G V Disease Phenylketonuria (PKU) [MIM:261600]
221 E G Disease Phenylketonuria (PKU) [MIM:261600]
222 D V Disease Phenylketonuria (PKU) [MIM:261600]
224 I M Disease Phenylketonuria (PKU) [MIM:261600]
225 P T Disease Phenylketonuria (PKU) [MIM:261600]
226 Q H Disease Phenylketonuria (PKU) [MIM:261600]
230 V I Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
231 S P Disease Phenylketonuria (PKU) [MIM:261600]
233 F L Disease Phenylketonuria (PKU) [MIM:261600]
238 T P Disease Phenylketonuria (PKU) [MIM:261600]
239 G S Disease Phenylketonuria (PKU) [MIM:261600]
240 F S Disease Phenylketonuria (PKU) [MIM:261600]
241 R L Disease Phenylketonuria (PKU) [MIM:261600]
242 L F Disease Phenylketonuria (PKU) [MIM:261600]
243 R Q Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
244 P L Disease Phenylketonuria (PKU) [MIM:261600]
245 V E Disease Phenylketonuria (PKU) [MIM:261600]
246 A D Disease Phenylketonuria (PKU) [MIM:261600]
247 G V Disease Phenylketonuria (PKU) [MIM:261600]
248 L P Disease Phenylketonuria (PKU) [MIM:261600]
249 L F Disease Phenylketonuria (PKU) [MIM:261600]
252 R W Disease Phenylketonuria (PKU) [MIM:261600]
255 L V Disease Phenylketonuria (PKU) [MIM:261600]
257 G C Disease Phenylketonuria (PKU) [MIM:261600]
259 A V Disease Phenylketonuria (PKU) [MIM:261600]
261 R Q Disease Hyperphenylalaninemia (HPA) [MIM:261600]
263 F L Disease Phenylketonuria (PKU) [MIM:261600]
264 H L Disease Phenylketonuria (PKU) [MIM:261600]
265 C G Disease Phenylketonuria (PKU) [MIM:261600]
269 I L Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
270 R K Disease Phenylketonuria (PKU) [MIM:261600]
271 H Y Disease Phenylketonuria (PKU) [MIM:261600]
273 S F Disease Phenylketonuria (PKU) [MIM:261600]
274 K E Polymorphism
275 P L Disease Phenylketonuria (PKU) [MIM:261600]
276 M I Disease Phenylketonuria (PKU) [MIM:261600]
277 Y C Disease Phenylketonuria (PKU) [MIM:261600]
278 T N Disease Phenylketonuria (PKU) [MIM:261600]
280 E K Disease Phenylketonuria (PKU) [MIM:261600]
281 P L Disease Phenylketonuria (PKU) [MIM:261600]
282 D N Disease Phenylketonuria (PKU) [MIM:261600]
283 I N Disease Phenylketonuria (PKU) [MIM:261600]
290 H Y Disease Phenylketonuria (PKU) [MIM:261600]
297 R C Disease Phenylketonuria (PKU) [MIM:261600]
299 F C Disease Phenylketonuria (PKU) [MIM:261600]
300 A S Disease Phenylketonuria (PKU) [MIM:261600]
303 S P Disease Phenylketonuria (PKU) [MIM:261600]
304 Q R Disease Phenylketonuria (PKU) [MIM:261600]
306 I V Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
309 A V Disease Phenylketonuria (PKU) [MIM:261600]
310 S Y Disease Hyperphenylalaninemia (HPA) [MIM:261600]
311 L P Disease Phenylketonuria (PKU) [MIM:261600]
314 P H Disease Phenylketonuria (PKU) [MIM:261600]
318 I T Disease Phenylketonuria (PKU) [MIM:261600]
322 A G Disease Phenylketonuria (PKU) [MIM:261600]
325 Y C Disease Phenylketonuria (PKU) [MIM:261600]
330 E D Disease Phenylketonuria (PKU) [MIM:261600]
331 F L Disease Phenylketonuria (PKU) [MIM:261600]
333 L F Disease Phenylketonuria (PKU) [MIM:261600]
334 C S Disease Phenylketonuria (PKU) [MIM:261600]
337 G V Disease Phenylketonuria (PKU) [MIM:261600]
338 D Y Disease Phenylketonuria (PKU) [MIM:261600]
341 K R Disease Phenylketonuria (PKU) [MIM:261600]
342 A T Disease Phenylketonuria (PKU) [MIM:261600]
343 Y C Disease Phenylketonuria (PKU) [MIM:261600]
344 G V Disease Phenylketonuria (PKU) [MIM:261600]
345 A T Disease Phenylketonuria (PKU) [MIM:261600]
347 L F Disease Phenylketonuria (PKU) [MIM:261600]
348 L V Disease Phenylketonuria (PKU) [MIM:261600]
349 S P Disease Phenylketonuria (PKU) [MIM:261600]
350 S T Disease Phenylketonuria (PKU) [MIM:261600]
357 C G Disease Phenylketonuria (PKU) [MIM:261600]
362 P T Disease Phenylketonuria (PKU) [MIM:261600]
366 P H Disease Phenylketonuria (PKU) [MIM:261600]
372 T S Disease Phenylketonuria (PKU) [MIM:261600]
377 Y C Disease Phenylketonuria (PKU) [MIM:261600]
380 T M Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
386 Y C Disease Phenylketonuria (PKU) [MIM:261600]
387 Y H Disease Phenylketonuria (PKU) [MIM:261600]
388 V M Disease Phenylketonuria (PKU) [MIM:261600]
390 E G Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
394 D A Disease Phenylketonuria (PKU) [MIM:261600]
395 A P Disease Phenylketonuria (PKU) [MIM:261600]
403 A V Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
407 P S Disease Phenylketonuria (PKU) [MIM:261600]
408 R W Disease Hyperphenylalaninemia (HPA) [MIM:261600]
410 F S Disease Phenylketonuria (PKU) [MIM:261600]
413 R P Disease Phenylketonuria (PKU) [MIM:261600]
414 Y C Disease Hyperphenylalaninemia (HPA) [MIM:261600]
415 D N Disease Hyperphenylalaninemia (HPA) [MIM:261600]
417 Y H Disease Phenylketonuria (PKU) [MIM:261600]
418 T P Disease Phenylketonuria (PKU) [MIM:261600]
421 I S Disease Phenylketonuria (PKU) [MIM:261600]
430 L P Disease Phenylketonuria (PKU) [MIM:261600]
447 A D Disease Phenylketonuria (PKU) [MIM:261600]