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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 3 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
88 TYR PRIDE
94 THR PRIDE
195 SER PRIDE yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 3 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
88 85 106 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
94 85 106 10 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
195 193 199 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD006482 1 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney

Structures

Showing 1 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
3OAI A X-ray 2.0999999046325684 Monomer [MAL]A:1122 0.1
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
88 1059 TYR E 1.0 111.03131103515625 0.0
94 1065 THR C 0.74 104.91276550292969 0.0

Mutations

Showing 65 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
30 I M Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
32 V F Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
34 T I Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
35 D Y Disease Charcot-Marie-Tooth disease, dominant, intermediate type, D (CMTDID) [MIM:607791]
39 H P Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
44 S F Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
51 S F Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
54 S C Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
56 E K Unclassified
58 V F Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
60 D H Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
61 D G Polymorphism
62 I F Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
63 S F Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
65 T I Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
68 Y C Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
75 D V Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
78 S L Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
81 H Y Polymorphism
82 Y C Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
89 I N Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
90 D E Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
92 V M Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
93 G E Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
96 K E Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
97 E V Disease Charcot-Marie-Tooth disease 2J (CMT2J) [MIM:607736]
98 R C Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
99 I T Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
101 W C Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
103 G E Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
109 D N Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
110 G D Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
112 I T Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
113 V I Unclassified
114 I T Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
116 N H Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
118 D N Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
119 Y C Polymorphism
122 N S Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
123 G C Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
124 T M Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
127 C Y Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
128 D E Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
130 K R Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
131 N K Disease Roussy-Levy syndrome (ROULS) [MIM:180800]
132 P L Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
134 D E Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
135 I L Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
136 V E Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
137 G S Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
138 K N Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
139 T N Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
140 S T Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
143 T M Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
145 Y S Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
146 V F Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
162 I M Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
163 G R Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
167 G R Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
170 L R Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
221 A T Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
224 D Y Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
227 R S Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
236 K E Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
244 R L Polymorphism