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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 3 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
172 SER PRIDE
185 SER PRIDE
269 SER PRIDE yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 4 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
172 164 194 9 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
185 164 194 22 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
269 256 275 14 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
269 267 275 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD002286 4 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 -

Structures

Showing 1 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
3PM0 A X-ray 2.700000047683716 Monomer [HEM]A:900 0.1041084 172, 185, 269
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
172 172 SER H 0.27 55.22835922241211 0.0
185 185 SER C 0.83 1.5564826726913452 0.0
269 269 SER H 0.65 23.9472713470459 0.0

Mutations

Showing 55 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
28 S W Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
48 R G Polymorphism
52 P L Polymorphism
57 W C Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
61 G E Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
68 Q R Polymorphism
77 L P Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
81 Y N Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
115 A P Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
119 A S Polymorphism
132 M R Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
144 Q P Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
145 R W Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
184 G S Polymorphism
189 A P Polymorphism
192 D V Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
193 P L Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
198 V I Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
203 N S Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
206 S N Polymorphism
215 S I Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
229 E K Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
232 G R Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
239 S R Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
266 R L Polymorphism
320 V L Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
330 A F Unclassified Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
345 L F Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
364 V M Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
365 G W Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
368 R H Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
374 D N Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
379 P L Polymorphism
387 E K Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
388 A T Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
390 R C Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
399 I S Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
409 V F Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
422 V G Polymorphism
423 N Y Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
432 L V Polymorphism
437 P L Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
441 D H Polymorphism
443 A G Unclassified Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
444 R Q Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
445 F C Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
449 D E Polymorphism
453 N S Polymorphism
466 G D Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
469 R W Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
499 E G Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
515 S L Unclassified Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
518 V A Polymorphism
523 R T Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]
530 D G Disease Glaucoma 3, primary congenital, A (GLC3A) [MIM:231300]