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FXR1_HUMAN : Fragile X mental retardation syndrome-related protein 1

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PDB 
 AlphaFold
Phospho-sites

Showing 25 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
68 TYR UP Similarity
125 THR PRIDE yes
401 THR UP, PRIDE Combined
403 SER UP, PRIDE Similarity yes
406 SER UP, PRIDE Combined
409 SER UP, PRIDE Combined
411 THR PRIDE
413 SER PRIDE yes
420 SER UP, PRIDE Combined
423 SER UP, PRIDE Combined
464 SER PRIDE
467 SER PRIDE yes
477 TYR PRIDE yes
483 THR UP, PRIDE Similarity
485 SER UP, PRIDE Combined yes
488 THR PRIDE yes
491 THR PRIDE yes
494 SER PRIDE
499 SER PRIDE yes
500 THR PRIDE yes
585 SER PRIDE yes
587 SER UP, PRIDE Combined yes
597 THR PRIDE yes
605 THR PRIDE
621 SER PRIDE

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 33 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
KNTFFK 125 123 128 3 1
RGPNYTSGYGTNSELSNPSETESERK 401 391 416 11 1
RGPNYTSGYGTNSELSNPSETESER 401 391 415 11 1
RGPNYTSGYGTNSELSNPSETESER 403 391 415 13 1
RGPNYTSGYGTNSELSNPSETESERK 406 391 416 16 2
RGPNYTSGYGTNSELSNPSETESER 406 391 415 16 7
RGPNYTSGYGTNSELSNPSETESER 409 391 415 19 9
RGPNYTSGYGTNSELSNPSETESERK 409 391 416 19 4
GPNYTSGYGTNSELSNPSETESER 409 392 415 18 1
GPNYTSGYGTNSELSNPSETESERK 409 392 416 18 1
RGPNYTSGYGTNSELSNPSETESERK 411 391 416 21 1
RGPNYTSGYGTNSELSNPSETESERK 413 391 416 23 1
KDELSDWSLAGEDDRDSR 420 416 433 5 4
DELSDWSLAGEDDRDSR 420 417 433 4 2
KDELSDWSLAGEDDRDSR 423 416 433 8 4
DELSDWSLAGEDDRDSR 423 417 433 7 2
DELSDWSLAGEDDR 423 417 430 7 1
SSISSVLK 464 463 470 2 5
SSISSVLK 467 463 470 5 2
DPDSNPYSLLDNTESDQTADTDASESHHSTNR 477 471 502 7 1
DPDSNPYSLLDNTESDQTADTDASESHHSTNR 483 471 502 13 2
DPDSNPYSLLDNTESDQTADTDASESHHSTNR 485 471 502 15 2
DPDSNPYSLLDNTESDQTADTDASESHHSTNRR 488 471 503 18 1
DPDSNPYSLLDNTESDQTADTDASESHHSTNR 491 471 502 21 1
DPDSNPYSLLDNTESDQTADTDASESHHSTNR 494 471 502 24 1
DPDSNPYSLLDNTESDQTADTDASESHHSTNR 499 471 502 29 1
DPDSNPYSLLDNTESDQTADTDASESHHSTNRR 499 471 503 29 1
DPDSNPYSLLDNTESDQTADTDASESHHSTNR 500 471 502 30 1
AINGPTSASGDDISK 585 579 593 7 1
AINGPTSASGDDISK 587 579 593 9 4
LQRTPGEEK 597 594 602 4 3
TPGEEKINTLKEENTQEAAVLNGVS 605 597 621 9 1
TPGEEKINTLKEENTQEAAVLNGVS 621 597 621 25 1

Structures

Showing 2 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
3O8V A X-ray 2.5 Monomer A 0.0
3KUF A X-ray 2.7 Monomer [GOL]A:137 0.12814464

Mutations

Showing 3 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
233 A T Unclassified A breast cancer sample
429 D N Polymorphism
614 A V Polymorphism