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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 17 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
58 SER UP, PRIDE Combined yes
65 THR PRIDE
75 THR PRIDE
117 SER UP, PRIDE Combined yes
143 SER UP, PRIDE Similarity yes
196 SER UP, PRIDE Similarity yes
210 THR UP, PRIDE Similarity yes
213 THR PRIDE yes
215 THR PRIDE yes
232 SER PRIDE yes
235 SER UP, PRIDE Similarity yes
241 SER PRIDE yes
246 TYR PRIDE yes
249 SER UP, PRIDE Combined yes
251 THR UP, PRIDE Combined yes
260 SER UP, PRIDE Combined yes
273 SER PRIDE yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 25 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
58 52 70 7 4
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 7 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
PXD004415 1 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte -
PXD003531 34 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD004452 22 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
58 56 70 3 18
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004252 8 Modulating the selectivity of affinity absorbents to multi-phosphopeptides by a novel competitive substitution strategy Homo sapiens (Human) PARTIAL 2016-08-03 cell culture -
PXD001060 457 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell -
PXD000474 8 Simulated phosphopeptide spectral library for confident site localization Homo sapiens (Human) PARTIAL 2015-03-17 HeLa cell -
PXD004940 8 Performance of the Orbitrap Fusion Lumos Tribrid in single-shot analyses of human samples Homo sapiens (Human) PARTIAL 2017-03-09 HeLa cell -
PXD003531 351 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD001333 10 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell -
PXD002286 4 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 -
PXD006482 59 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney -
PXD005366 70 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture -
PXD001550 136 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD002394 28 Proteomic and phosphoproteomic analysis of cisplatin resistance in patient derived serous ovarian cancer Homo sapiens (Human) PARTIAL 2017-05-02 cell suspension culture -
PXD004452 71 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
PXD000680 39 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -
PXD000836 66 HOPE-fixation of lung tissue allows retrospective proteome and phosphoproteome studies Homo sapiens (Human) PARTIAL 2014-05-22 lung -
PXD000612 70 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD002436 3 Monitoring cellular phosphorylation signaling pathways into chromatin and down to the gene level Homo sapiens (Human) COMPLETE 2015-11-09 HeLa cell -
PXD004415 96 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte -
PXD001546 78 Reproducibility of label-free single-shot phosphoproteomics applied to CRC cell lines Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
58 56 90 3 4
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 24 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell -
PXD004415 22 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte -
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
PXD000680 3 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
58 57 70 2 11
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 2 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell -
PXD000836 5 HOPE-fixation of lung tissue allows retrospective proteome and phosphoproteome studies Homo sapiens (Human) PARTIAL 2014-05-22 lung
PXD000612 26 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004415 7 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte -
PXD001546 4 Reproducibility of label-free single-shot phosphoproteomics applied to CRC cell lines Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD003531 4 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD001333 3 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell -
PXD002286 37 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 - -
PXD006482 4 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney -
PXD001550 7 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD004452 8 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
65 56 90 10 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 1 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell
65 57 70 9 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
65 57 90 9 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 3 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
75 56 90 20 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 4 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell
PXD004415 1 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte -
75 57 90 19 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 3 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
117 107 122 11 10
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 2 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell -
PXD004252 1 Modulating the selectivity of affinity absorbents to multi-phosphopeptides by a novel competitive substitution strategy Homo sapiens (Human) PARTIAL 2016-08-03 cell culture -
PXD000612 68 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001546 6 Reproducibility of label-free single-shot phosphoproteomics applied to CRC cell lines Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD004940 2 Performance of the Orbitrap Fusion Lumos Tribrid in single-shot analyses of human samples Homo sapiens (Human) PARTIAL 2017-03-09 HeLa cell -
PXD003531 9 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD006482 1 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney
PXD005366 5 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture -
PXD001550 3 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD004452 11 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
143 138 150 6 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD006482 1 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney
196 187 212 10 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD006482 2 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney
210 198 212 13 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
213 213 225 1 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
215 213 225 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 22 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
232 226 243 7 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
232 228 243 5 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD006482 2 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney
232 232 243 1 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 9 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD002286 8 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 -
PXD006482 1 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney -
235 232 243 4 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD002286 2 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 -
PXD006482 2 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney -
241 232 243 10 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD006482 1 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney
PXD002286 1 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 - -
246 244 256 3 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001565 1 Evaluation of phospho-tyrosine antibodies for label-free phosphoproteomics Homo sapiens (Human) PARTIAL 2015-12-09 colon,brain
249 244 256 6 4
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD006482 15 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney -
PXD005366 1 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture -
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
251 244 256 8 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD006482 1 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney
260 257 285 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004415 1 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte
273 257 285 17 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004415 2 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte
PXD004452 2 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -

Structures

Showing 14 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
4UNL A X-ray 1.5 2 B 1.0 251, 273
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
58 20 SER H 0.43 61.80039596557617 0.0
65 27 THR H 0.95 61.38856506347656 0.0
75 37 THR E 0.94 17.893247604370117 0.0
117 79 SER C 1.0 4.562506675720215 4.562506675720215
143 105 SER C 1.0 57.54476547241211 0.0
196 158 SER H 0.6 89.47685241699219 0.0
210 172 THR C 1.0 58.12727355957031 0.0
213 175 THR C 1.0 112.97142028808594 0.0
215 177 THR C 1.0 56.69239044189453 0.0
232 194 SER H 0.72 96.25057220458984 0.0
235 197 SER C 0.94 40.58253479003906 0.0
241 203 SER H 0.83 60.8662223815918 0.0
246 208 TYR E 1.0 2.698439359664917 0.0
249 211 SER C 1.0 92.7757797241211 0.0
251 213 THR C 1.0 51.64019775390625 0.0
254 216 THR C 0.87 57.747642517089844 0.0
260 222 SER H 0.9 77.04749298095703 0.0
273 235 SER H 1.0 0.0 0.0
4POC A X-ray 1.600000023841858 2 [K]A:301 0.7194396 251, 273
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
58 20 SER H 0.43 59.61119842529297 0.0
65 27 THR H 0.95 50.84693145751953 0.0
75 37 THR E 0.94 9.082420349121094 0.0
117 79 SER C 1.0 4.686465263366699 0.0
143 105 SER C 1.0 58.25884246826172 0.0
196 158 SER H 0.6 85.59559631347656 0.0
210 172 THR C 1.0 54.3834114074707 0.0
213 175 THR C 1.0 110.83702087402344 0.0
215 177 THR C 1.0 53.07986068725586 0.0
232 194 SER H 0.72 86.00567626953125 0.0
235 197 SER C 0.94 42.61290740966797 0.0
241 203 SER H 0.83 70.63289642333984 0.0
246 208 TYR E 1.0 3.8075997829437256 0.0
249 211 SER C 1.0 82.62564086914062 0.0
251 213 THR C 1.0 57.26301193237305 0.0
254 216 THR C 0.87 59.997886657714844 0.0
260 222 SER C 0.9 70.83082580566406 2.0879342555999756
273 235 SER H 1.0 0.0 0.0
4ZVJ A X-ray 1.7000000476837158 2 B 0.23193341 251, 273
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
58 20 SER H 0.43 52.652122497558594 0.0
65 27 THR H 0.95 53.67570495605469 0.0
75 37 THR E 0.94 4.662531852722168 0.0
117 79 SER C 1.0 4.780453681945801 4.780453681945801
143 105 SER C 1.0 56.804630279541016 0.0
196 158 SER H 0.6 85.82315826416016 0.0
210 172 THR C 1.0 55.23813247680664 0.0
213 175 THR C 1.0 110.72054290771484 0.0
215 177 THR C 1.0 61.501346588134766 0.0
232 194 SER H 0.72 87.76315307617188 0.0
235 197 SER C 0.94 41.26682662963867 0.0
241 203 SER H 0.83 58.66101837158203 0.0
246 208 TYR E 1.0 4.933102130889893 0.0
249 211 SER C 1.0 95.2719497680664 0.0
251 213 THR C 1.0 47.20187759399414 0.0
254 216 THR C 0.87 58.302146911621094 0.0
260 222 SER C 0.9 76.27344512939453 0.0
273 235 SER H 1.0 0.0 0.0
2JK2 A X-ray 1.7000000476837158 2 B 1.0 251, 273
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
58 20 SER H 0.43 55.80789566040039 0.0
65 27 THR H 0.95 54.58443069458008 0.0
75 37 THR E 0.94 7.122260570526123 0.0
117 79 SER C 1.0 4.933669090270996 4.933669090270996
143 105 SER C 1.0 56.21660614013672 0.0
196 158 SER H 0.6 89.03099060058594 0.0
210 172 THR C 1.0 52.77052307128906 0.0
213 175 THR C 1.0 111.51260375976562 0.0
215 177 THR C 1.0 62.16345977783203 0.0
232 194 SER C 0.72 92.28157043457031 0.0
235 197 SER C 0.94 41.634178161621094 0.0
241 203 SER H 0.83 60.166622161865234 0.0
246 208 TYR E 1.0 4.937776565551758 0.0
249 211 SER C 1.0 88.01348114013672 0.0
251 213 THR C 1.0 46.98399353027344 0.0
254 216 THR C 0.87 56.73392868041992 0.0
260 222 SER C 0.9 76.77979278564453 0.0
273 235 SER H 1.0 0.0 0.0
2VOM A X-ray 1.850000023841858 2 B 1.0 251, 273
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
58 20 SER H 0.43 52.4772834777832 0.0
65 27 THR H 0.95 57.06129837036133 0.0
75 37 THR E 0.94 10.308317184448242 0.0
117 79 SER C 1.0 4.864145755767822 4.864145755767822
143 105 SER C 1.0 55.45552444458008 0.0
196 158 SER H 0.6 84.2884292602539 0.0
210 172 THR C 1.0 54.84477996826172 0.0
213 175 THR C 1.0 105.15924072265625 0.0
215 177 THR C 1.0 52.237220764160156 0.0
232 194 SER H 0.72 94.81182861328125 0.0
235 197 SER C 0.94 41.82334518432617 0.0
241 203 SER H 0.83 69.22604370117188 0.0
246 208 TYR E 1.0 3.212193012237549 0.0
249 211 SER C 1.0 97.40945434570312 0.0
251 213 THR C 1.0 51.12767791748047 0.0
254 216 THR C 0.87 62.03360366821289 0.0
260 222 SER C 0.9 78.05317687988281 0.0
273 235 SER H 1.0 0.0 0.0
4POD A X-ray 1.9900000095367432 2 [K]A:301 0.7351645 251, 273
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
58 20 SER H 0.43 56.22933578491211 0.0
65 27 THR H 0.95 52.365135192871094 0.0
75 37 THR E 0.94 6.260948181152344 0.0
117 79 SER C 1.0 4.5659356117248535 0.0
143 105 SER C 1.0 48.07504653930664 0.0
196 158 SER H 0.6 86.6778793334961 0.0
210 172 THR C 1.0 49.40020751953125 0.0
213 175 THR C 1.0 107.87589263916016 0.0
215 177 THR C 1.0 46.86677551269531 0.0
232 194 SER H 0.72 95.20052337646484 0.0
235 197 SER C 0.94 40.96167755126953 0.0
241 203 SER H 0.83 64.07393646240234 0.0
246 208 TYR E 1.0 6.3257155418396 0.0
249 211 SER C 1.0 97.85302734375 0.0
251 213 THR C 1.0 51.03656768798828 0.0
254 216 THR C 0.87 62.4652214050293 0.0
260 222 SER C 0.9 78.04695892333984 4.243400573730469
273 235 SER H 1.0 0.0 0.0
4UNK A X-ray 2.0 2 B 1.0 251, 273
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
58 20 SER H 0.43 55.2064208984375 0.0
65 27 THR H 0.95 61.07147216796875 0.0
75 37 THR E 0.94 11.363076210021973 0.0
117 79 SER C 1.0 27.999631881713867 15.310982704162598
143 105 SER C 1.0 58.25373840332031 0.0
196 158 SER H 0.6 87.30341339111328 0.0
210 172 THR C 1.0 59.97968292236328 0.0
213 175 THR C 1.0 110.39763641357422 0.0
215 177 THR C 1.0 58.63825607299805 0.0
232 194 SER H 0.72 94.02181243896484 0.0
235 197 SER C 0.94 40.84086227416992 0.0
241 203 SER H 0.83 66.89786529541016 0.0
246 208 TYR E 1.0 5.847409248352051 0.0
249 211 SER C 1.0 85.84717559814453 0.0
251 213 THR C 1.0 48.98834991455078 0.0
254 216 THR C 0.87 59.486183166503906 0.0
260 222 SER C 0.9 80.0030517578125 0.0
273 235 SER H 1.0 0.0 0.0
6D43 A X-ray 2.0399999618530273 2 B 1.0 251, 273
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
58 20 SER H 0.43 58.07577896118164 0.0
65 27 THR H 0.95 52.03805160522461 0.0
75 37 THR E 0.94 4.295413017272949 0.0
117 79 SER C 1.0 4.6385674476623535 4.6385674476623535
143 105 SER C 1.0 56.997833251953125 0.0
196 158 SER H 0.6 90.11390686035156 0.0
210 172 THR C 1.0 57.56667709350586 0.0
213 175 THR C 1.0 108.42688751220703 0.0
215 177 THR C 1.0 61.706947326660156 0.0
232 194 SER H 0.72 95.08152770996094 0.0
235 197 SER C 0.94 41.04975509643555 0.0
241 203 SER H 0.83 70.9803237915039 0.0
246 208 TYR E 1.0 5.591666221618652 0.0
249 211 SER C 1.0 94.1657943725586 0.0
251 213 THR C 1.0 50.71674728393555 0.0
254 216 THR C 0.87 64.04356384277344 0.0
260 222 SER C 0.9 74.89881134033203 0.0
273 235 SER H 1.0 0.0 0.0
1WYI A X-ray 2.200000047683716 2 B 1.0 251, 273
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
58 20 SER H 0.43 55.150211334228516 0.0
65 27 THR H 0.95 48.33147430419922 0.0
75 37 THR E 0.94 8.055195808410645 0.0
117 79 SER C 1.0 5.1430463790893555 5.1430463790893555
143 105 SER C 1.0 57.005897521972656 0.0
196 158 SER C 0.6 86.7324447631836 0.0
210 172 THR C 1.0 45.05391311645508 0.0
213 175 THR C 1.0 115.84663391113281 0.0
215 177 THR C 1.0 54.61970901489258 0.0
232 194 SER H 0.72 90.09073638916016 0.0
235 197 SER C 0.94 43.608848571777344 0.0
241 203 SER H 0.83 57.98563766479492 0.0
246 208 TYR E 1.0 4.403378486633301 0.0
249 211 SER C 1.0 98.53164672851562 0.0
251 213 THR C 1.0 49.86091232299805 0.0
254 216 THR C 0.87 54.38192367553711 0.0
260 222 SER H 0.9 81.683349609375 0.0
273 235 SER H 1.0 0.0 0.0
6C2G A X-ray 2.299999952316284 2 C 1.0 251, 273
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
58 20 SER H 0.43 56.458648681640625 0.0
65 27 THR H 0.95 77.58987426757812 0.0
75 37 THR E 0.94 9.205111503601074 0.0
117 79 SER C 1.0 5.950374126434326 5.950374126434326
143 105 SER C 1.0 60.341732025146484 0.0
196 158 SER H 0.6 94.00120544433594 0.0
210 172 THR C 1.0 64.93807220458984 0.0
213 175 THR C 1.0 112.3680648803711 0.0
215 177 THR C 1.0 60.1512451171875 0.0
232 194 SER H 0.72 96.03475952148438 0.0
235 197 SER C 0.94 43.6390495300293 0.0
241 203 SER H 0.83 69.84432220458984 0.0
246 208 TYR E 1.0 4.3658928871154785 0.0
249 211 SER C 1.0 92.89907836914062 0.0
251 213 THR C 1.0 52.495784759521484 0.0
254 216 THR C 0.87 60.09904098510742 0.0
260 222 SER C 0.9 83.27540588378906 0.0
273 235 SER H 1.0 0.0 0.0
1HTI A X-ray 2.799999952316284 2 B 0.81867284 251, 273
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
58 20 SER H 0.43 56.626991271972656 0.0
65 27 THR H 0.95 53.64570236206055 0.0
75 37 THR E 0.94 7.543721675872803 0.0
117 79 SER C 1.0 5.927151679992676 5.927151679992676
143 105 SER C 1.0 63.89391326904297 0.0
196 158 SER C 0.6 81.79689025878906 0.0
210 172 THR C 1.0 53.816932678222656 0.0
213 175 THR C 1.0 110.28934478759766 0.0
215 177 THR C 1.0 61.40230941772461 0.0
232 194 SER H 0.72 87.96428680419922 0.0
235 197 SER C 0.94 35.30292892456055 0.0
241 203 SER C 0.83 66.11690521240234 0.0
246 208 TYR E 1.0 5.029330730438232 0.0
249 211 SER C 1.0 95.13629913330078 0.0
251 213 THR C 1.0 49.1298828125 0.0
254 216 THR C 0.87 52.44192886352539 0.0
260 222 SER C 0.9 77.61429595947266 0.0
273 235 SER H 1.0 0.0 0.0
4BR1 A X-ray 1.899999976158142 2 B 1.0 273
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
58 20 SER H 0.43 58.549072265625 0.0
65 27 THR H 0.95 58.44155502319336 0.0
75 37 THR E 0.94 7.864107608795166 0.0
117 79 SER C 1.0 5.209481716156006 5.209481716156006
143 105 SER C 1.0 57.73988342285156 0.0
196 158 SER H 0.6 89.27347564697266 0.0
215 177 THR C 1.0 95.54618835449219 0.0
232 194 SER H 0.72 97.14015197753906 0.0
235 197 SER C 0.94 41.56739807128906 0.0
241 203 SER H 0.83 63.257354736328125 0.0
246 208 TYR E 1.0 16.560701370239258 0.0
249 211 SER C 1.0 89.39201354980469 0.0
251 213 THR C 1.0 52.41154098510742 0.0
254 216 THR C 0.87 65.58612060546875 0.0
260 222 SER C 0.9 75.48096466064453 0.0
273 235 SER H 1.0 0.1231222152709961 0.0
1KLU C X-ray 1.9299999475479126 3 A 1.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
65 28 THR C 0.95 121.02122497558594 78.81568145751953
2IAN C X-ray 2.799999952316284 3 A 0.17855443
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
65 28 THR C 0.95 127.57762145996094 76.72831726074219

Mutations

Showing 8 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
79 C Y Disease Triosephosphate isomerase deficiency (TPID) [MIM:615512]
110 G A Disease Triosephosphate isomerase deficiency (TPID) [MIM:615512]
142 E D Disease Triosephosphate isomerase deficiency (TPID) [MIM:615512]
160 G R Polymorphism
192 V M Disease Triosephosphate isomerase deficiency (TPID) [MIM:615512]
208 I V Disease Triosephosphate isomerase deficiency (TPID) [MIM:615512]
269 V M Disease Triosephosphate isomerase deficiency (TPID) [MIM:615512]
278 F L Disease Triosephosphate isomerase deficiency (TPID) [MIM:615512]