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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 5 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
53 TYR PRIDE yes
89 SER PRIDE yes
113 SER UP, PRIDE Combined yes
115 SER PRIDE yes
130 THR UP, PRIDE Combined yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 7 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
53 50 59 4 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 2 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001565 1 Evaluation of phospho-tyrosine antibodies for label-free phosphoproteomics Homo sapiens (Human) PARTIAL 2015-12-09 colon,brain
89 82 103 8 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -
113 108 132 6 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004415 2 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte
113 108 129 6 8
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 22 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004415 13 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte -
PXD003531 20 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD002286 53 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 - -
PXD005366 2 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture -
PXD001550 3 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD004452 19 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
115 108 129 8 5
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 6 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004415 7 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte -
PXD003531 2 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD002286 31 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 -
PXD001550 9 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
115 108 132 8 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004415 5 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte
130 108 132 23 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 5 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001333 2 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell
PXD004452 3 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -

Structures

Showing 6 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
6G5H R EM 3.5999999046325684 Monomer 2 0.0 53, 89, 113, 115, 130
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
53 53 TYR H 0.9 24.036407470703125 19.722463607788086
89 89 SER C 1.0 45.20039749145508 0.0
113 113 SER C 0.83 104.54520416259766 0.0
115 115 SER C 0.67 107.40484619140625 0.0
120 120 THR C 0.82 63.822566986083984 0.0
130 130 THR C 0.61 108.2044448852539 0.0
5A2Q R EM 3.9000000953674316 Monomer 2 0.0 53, 89, 113, 115, 130
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
53 53 TYR H 0.9 30.629114151000977 16.112001419067383
89 89 SER C 1.0 58.64342498779297 0.0
113 113 SER C 0.83 96.60649871826172 0.0
115 115 SER C 0.67 106.35155487060547 0.0
120 120 THR C 0.82 46.787879943847656 0.0
130 130 THR C 0.61 117.76582336425781 0.0
5OA3 R EM 4.300000190734863 Monomer 2 0.0 53, 89, 113, 115, 130
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
53 53 TYR H 0.9 26.78539276123047 16.007352828979492
89 89 SER C 1.0 58.36765670776367 0.0
113 113 SER C 0.83 98.44501495361328 0.0
115 115 SER C 0.67 103.80809783935547 0.0
120 120 THR C 0.82 43.70182418823242 0.0
130 130 THR C 0.61 120.0999755859375 0.0
6G5I R EM 3.5 Monomer 2 0.0 53, 89, 113, 115
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
53 53 TYR H 0.9 16.591909408569336 15.920361518859863
89 89 SER C 1.0 60.34033203125 0.0
113 113 SER C 0.83 103.66923522949219 0.0
115 115 SER C 0.67 112.6471939086914 0.0
120 120 THR C 0.82 57.03433609008789 0.0
6G18 R EM 3.5999999046325684 Monomer 2 0.0 53, 89, 113, 115
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
53 53 TYR H 0.9 15.713118553161621 8.136064529418945
89 89 SER C 1.0 58.25605773925781 0.0
113 113 SER C 0.83 112.36651611328125 0.0
115 115 SER C 0.67 103.81412506103516 0.0
120 120 THR C 0.82 61.58367156982422 0.0
5FLX R EM 3.9000000953674316 Monomer 1 0.0 53, 89, 113, 115
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
53 53 TYR H 0.9 33.4280891418457 21.324325561523438
89 89 SER C 1.0 100.4760971069336 0.0
113 113 SER C 0.83 107.21143341064453 0.0
115 115 SER C 0.67 117.87690734863281 0.0
120 120 THR C 0.82 94.70947265625 0.0

Mutations

Showing 1 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
36 E K Polymorphism