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PDB 
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Phospho-sites

Showing 8 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
460 THR PRIDE yes
614 SER PRIDE yes
1043 SER PRIDE yes
1056 SER PRIDE yes
1238 TYR UP, PRIDE Experimental
1239 TYR UP, PRIDE Experimental
1240 SER PRIDE
1353 TYR UP Experimental

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 11 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
460 456 470 5 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 1 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell
614 587 621 28 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
1043 1019 1053 25 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001550 1 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
1056 1054 1060 3 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 8 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
1056 1055 1071 2 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
1056 1055 1060 2 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003531 1 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell
1238 1232 1245 7 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
PXD003198 65 Characterisation of pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling Homo sapiens (Human) PARTIAL 2016-06-09 pancreatic cell line -
1238 1237 1245 2 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003198 4 Characterisation of pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling Homo sapiens (Human) PARTIAL 2016-06-09 pancreatic cell line
1239 1232 1245 8 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001565 1 Evaluation of phospho-tyrosine antibodies for label-free phosphoproteomics Homo sapiens (Human) PARTIAL 2015-12-09 colon,brain
PXD003198 31 Characterisation of pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling Homo sapiens (Human) PARTIAL 2016-06-09 pancreatic cell line -
1239 1237 1245 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003198 4 Characterisation of pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling Homo sapiens (Human) PARTIAL 2016-06-09 pancreatic cell line
1240 1232 1245 9 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003198 9 Characterisation of pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling Homo sapiens (Human) PARTIAL 2016-06-09 pancreatic cell line

Structures

Showing 3 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
3PLS A X-ray 2.240000009536743 Monomer [MG]A:1 0.03615239 1238, 1239, 1240, 1353
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
1064 1064 SER H 0.58 89.73236083984375 0.0
1238 1238 TYR H 1.0 27.492511749267578 0.0
1239 1239 TYR H 1.0 1.4401168823242188 0.0
1240 1240 SER C 1.0 35.79214859008789 0.0
1353 1353 TYR E 1.0 151.6790313720703 0.0
4QT8 A X-ray 3.0 Monomer C 0.0 460, 614
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
460 460 THR C 1.0 3.305330753326416 0.0
614 614 SER C 0.86 33.101444244384766 0.0
4FWW A X-ray 1.850000023841858 2 [SO4]A:605 0.40478227 460
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
460 460 THR E 1.0 2.3288955688476562 0.0

Mutations

Showing 20 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
75 R S Polymorphism
95 P T Polymorphism
185 R C Polymorphism
306 R H Disease Nasopharyngeal carcinoma, 3 (NPCA3) [MIM:617075]
322 R Q Polymorphism
327 A T Unclassified Nasopharyngeal carcinoma, 3 (NPCA3) [MIM:617075]
356 G D Polymorphism
434 S L Polymorphism
440 N S Polymorphism
465 G D Polymorphism
504 R C Polymorphism
523 Q R Polymorphism
613 Q P Polymorphism
670 V G Unclassified Nasopharyngeal carcinoma, 3 (NPCA3) [MIM:617075]
900 V M Polymorphism
973 A T Unclassified Nasopharyngeal carcinoma, 3 (NPCA3) [MIM:617075]
1195 G S Polymorphism
1304 R G Polymorphism
1335 R G Polymorphism
1360 Y C Polymorphism