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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 12 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
77 SER PRIDE yes
85 SER PRIDE yes
133 TYR PRIDE yes
252 THR UP, PRIDE Combined yes
262 THR PRIDE yes
264 SER UP, PRIDE Combined yes
266 TYR PRIDE yes
270 THR UP Combined
276 THR PRIDE yes
281 SER UP, PRIDE Combined yes
292 THR PRIDE yes
293 THR PRIDE yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 13 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
77 75 89 3 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
PXD001550 3 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
77 77 89 1 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003531 8 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD002286 5 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 - -
PXD004452 3 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
85 77 89 9 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
133 126 142 8 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 50 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001565 11 Evaluation of phospho-tyrosine antibodies for label-free phosphoproteomics Homo sapiens (Human) PARTIAL 2015-12-09 colon,brain
PXD003198 3 Characterisation of pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling Homo sapiens (Human) PARTIAL 2016-06-09 pancreatic cell line -
252 247 257 6 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD005366 4 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture
262 258 275 5 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD005366 1 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture
264 258 275 7 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD005366 3 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
264 264 275 1 7
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 5 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell -
PXD000612 110 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004940 1 Performance of the Orbitrap Fusion Lumos Tribrid in single-shot analyses of human samples Homo sapiens (Human) PARTIAL 2017-03-09 HeLa cell -
PXD003531 16 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD001333 3 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell
PXD005366 15 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture -
PXD004452 4 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
266 264 275 3 6
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 1 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell -
PXD000612 28 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
PXD001565 2 Evaluation of phospho-tyrosine antibodies for label-free phosphoproteomics Homo sapiens (Human) PARTIAL 2015-12-09 colon,brain -
PXD005366 3 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture -
PXD004452 3 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
PXD000680 3 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -
276 276 284 1 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
281 276 284 6 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 5 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD003531 2 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell
PXD005366 3 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture -
292 285 293 8 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 3 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
293 285 293 9 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 12 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
PXD001333 4 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell -

Structures

Showing 6 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
6G5I C EM 3.5 Monomer 2 0.0 77, 85, 133, 252, 262, 264, 266, 270, 276
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
77 77 SER C 0.8 48.269718170166016 0.0
85 85 SER C 1.0 93.353271484375 0.0
133 133 TYR C 1.0 73.97848510742188 0.0
252 252 THR C 1.0 15.38346004486084 0.0
262 262 THR C 0.88 89.77376556396484 0.0
264 264 SER C 1.0 23.76508903503418 0.0
266 266 TYR H 1.0 80.2289810180664 0.0
270 270 THR C 1.0 79.13899230957031 0.0
276 276 THR C 0.87 155.14541625976562 0.0
6G5H C EM 3.5999999046325684 Monomer 2 0.0 77, 85, 133, 252, 262, 264, 266, 270, 276
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
77 77 SER C 0.8 57.457862854003906 0.0
85 85 SER C 1.0 88.25765228271484 0.0
133 133 TYR C 1.0 94.90232849121094 0.0
252 252 THR C 1.0 15.395322799682617 0.0
262 262 THR C 0.88 98.3729476928711 0.0
264 264 SER C 1.0 33.902408599853516 0.0
266 266 TYR H 1.0 80.76576232910156 0.0
270 270 THR C 1.0 69.7332992553711 0.0
276 276 THR C 0.87 112.1954345703125 0.0
6G18 C EM 3.5999999046325684 Monomer 2 0.0 77, 85, 133, 252, 262, 264, 266, 270, 276
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
77 77 SER C 0.8 42.1426887512207 0.0
85 85 SER C 1.0 97.93183898925781 0.0
133 133 TYR C 1.0 83.29243469238281 0.0
252 252 THR C 1.0 19.026920318603516 0.0
262 262 THR C 0.88 90.14702606201172 0.0
264 264 SER C 1.0 30.47125816345215 0.0
266 266 TYR H 1.0 75.08086395263672 0.0
270 270 THR C 1.0 77.4974136352539 0.0
276 276 THR C 0.87 105.74310302734375 0.0
5FLX C EM 3.9000000953674316 Monomer 1 0.0 77, 85, 133, 252, 262, 264, 266, 270, 276
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
77 77 SER C 0.8 45.59114456176758 0.0
85 85 SER C 1.0 95.24629211425781 0.0
133 133 TYR C 1.0 103.08820343017578 0.0
252 252 THR C 1.0 27.2542781829834 0.0
262 262 THR C 0.88 81.8064956665039 0.0
264 264 SER C 1.0 36.5325927734375 0.0
266 266 TYR H 1.0 53.871238708496094 0.0
270 270 THR H 1.0 52.5098991394043 0.0
276 276 THR H 0.87 63.4151496887207 0.0
278 278 THR C 0.76 132.2153778076172 0.0
5A2Q C EM 3.9000000953674316 Monomer 2 0.0 77, 85, 133, 252, 262, 264, 266, 270, 276
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
77 77 SER C 0.8 43.59589767456055 0.0
85 85 SER C 1.0 92.87028503417969 0.0
133 133 TYR C 1.0 100.12109375 0.0
252 252 THR C 1.0 24.666954040527344 0.0
262 262 THR C 0.88 84.28922271728516 0.0
264 264 SER C 1.0 35.13600540161133 0.0
266 266 TYR H 1.0 74.67044830322266 0.0
270 270 THR H 1.0 64.83692169189453 0.0
276 276 THR C 0.87 109.0561294555664 0.0
5OA3 C EM 4.300000190734863 Monomer 2 0.0 77, 85, 133, 252, 262, 264, 266, 270, 276
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
77 77 SER C 0.8 38.455772399902344 0.0
85 85 SER C 1.0 94.54649353027344 0.0
133 133 TYR C 1.0 101.76732635498047 0.0
252 252 THR C 1.0 23.290002822875977 0.0
262 262 THR C 0.88 93.02711486816406 0.0
264 264 SER C 1.0 35.070613861083984 0.0
266 266 TYR H 1.0 77.26146697998047 0.0
270 270 THR H 1.0 62.33209228515625 0.0
276 276 THR C 0.87 109.97625732421875 0.0

Mutations

Showing 0 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease