Welcome to Scop3P

Search for the desired protein with Uniprot accession, protein name/keyword, ProteomeXchange ID or PDB id

Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

  • Zoom in and zoom out (both with mouse and buttons on the right top corner) to see modificationson the protein
  • Slide the chart to see other modifications (both with mouse and buttons on the right topcorner)
  • Hover on the modification to see more information and position on the structure.
PDB 
 AlphaFold
Phospho-sites

Showing 4 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
163 THR PRIDE yes
309 SER PRIDE yes
377 THR PRIDE yes
378 TYR PRIDE yes

3D structure is not available

Display Settings

Hover over to see the values, zoom (in/out) or drag by using the mouse pointer.

Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 4 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
163 160 167 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004940 1 Performance of the Orbitrap Fusion Lumos Tribrid in single-shot analyses of human samples Homo sapiens (Human) PARTIAL 2017-03-09 HeLa cell
309 309 333 1 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
377 375 385 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000836 5 HOPE-fixation of lung tissue allows retrospective proteome and phosphoproteome studies Homo sapiens (Human) PARTIAL 2014-05-22 lung
378 375 385 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000836 1 HOPE-fixation of lung tissue allows retrospective proteome and phosphoproteome studies Homo sapiens (Human) PARTIAL 2014-05-22 lung

Structures

Showing 2 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
5FO8 C X-ray 2.4000000953674316 3 A 0.20835838 163
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
163 163 THR C 0.26 110.06961059570312 0.0
3O8E B X-ray 2.8399999141693115 12 A 0.4223569
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
163 129 THR C 0.26 106.82837677001953 0.0

Mutations

Showing 12 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
13 S F Polymorphism
35 C Y Disease Hemolytic uremic syndrome atypical 2 (AHUS2) [MIM:612922]
59 R Q Polymorphism
165 P S Disease Hemolytic uremic syndrome atypical 2 (AHUS2) [MIM:612922]
216 W C Disease Hemolytic uremic syndrome atypical 2 (AHUS2) [MIM:612922]
228 C Y Unclassified A colorectal cancer sample
231 P R Disease Hemolytic uremic syndrome atypical 2 (AHUS2) [MIM:612922]
240 S P Disease Hemolytic uremic syndrome atypical 2 (AHUS2) [MIM:612922]
266 D N Polymorphism
324 P L Polymorphism
353 A V Polymorphism
355 V G Polymorphism