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Search for the desired protein with Uniprot accession, protein name/keyword, ProteomeXchange ID or PDB id

Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

MUS81_HUMAN : Crossover junction endonuclease MUS81

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PDB

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Phospho-sites

Showing 4 results

Swiss-Prot Position	Modification	Source	Evidence	Singly phosphorylated
95	SER	UP, PRIDE	Combined
97	SER	PRIDE		yes
101	SER	UP, PRIDE	Combined
343	SER	PRIDE		yes

Swiss-Prot Position

Modification

Source

Evidence

Singly phosphorylated

SER

UP, PRIDE

Combined

SER

PRIDE

yes

101

SER

UP, PRIDE

Combined

343

SER

PRIDE

yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 4 results

Sequence

Modified position (Swiss-Prot)

Peptide start

Peptide end

Modified position (Peptide)

Number of projects

TSGGDHAPDSPSGENSPAPQGR

107

ProteomeXchange accession	Peptide frequency	Project Title	Species	Submission Type	Publication Date	Tissues	USI
PXD004252	5	Modulating the selectivity of affinity absorbents to multi-phosphopeptides by a novel competitive substitution strategy	Homo sapiens (Human)	PARTIAL	2016-08-03	cell culture	-
PXD001060	1	Fe-IMAC column based phospho enrichment	Homo sapiens (Human)	PARTIAL	2015-08-19	Epithelial cell	-
PXD000612	3	Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling	Homo sapiens (Human)	PARTIAL	2014-08-06	cell culture	-
PXD001546	3	Reproducibility of label-free single-shot phosphoproteomics applied to CRC cell lines	Homo sapiens (Human)	PARTIAL	2015-04-15	cell culture	-
PXD004940	5	Performance of the Orbitrap Fusion Lumos Tribrid in single-shot analyses of human samples	Homo sapiens (Human)	PARTIAL	2017-03-09	HeLa cell	-
PXD003531	9	Proteomics of Primary cells derived from Ovarian Cancer	Homo sapiens (Human)	PARTIAL	2017-04-03	primary cell	-
PXD001333	1	Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC	Homo sapiens (Human)	PARTIAL	2015-04-23	HeLa cell	-
PXD005366	24	Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons	Homo sapiens (Human),Rattus norvegicus (Rat)	PARTIAL	2016-12-14	cell culture	-
PXD001374	4	Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling	Homo sapiens (Human)	PARTIAL	2015-08-24	HeLa cell
PXD001550	10	Human CRC cell line baseline phosphoproteomics	Homo sapiens (Human)	PARTIAL	2015-04-15	cell culture	-
PXD004452	3	HeLa proteome of 12,250 protein-coding genes	Homo sapiens (Human)	PARTIAL	2017-06-12	liver,colon	-
PXD000680	4	Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination	Homo sapiens (Human)	COMPLETE	2014-04-15	HeLa cell,HEK-293 cell	-

TSGGDHAPDSPSGENSPAPQGR

107

ProteomeXchange accession	Peptide frequency	Project Title	Species	Submission Type	Publication Date	Tissues	USI
PXD001546	1	Reproducibility of label-free single-shot phosphoproteomics applied to CRC cell lines	Homo sapiens (Human)	PARTIAL	2015-04-15	cell culture	-
PXD005366	1	Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons	Homo sapiens (Human),Rattus norvegicus (Rat)	PARTIAL	2016-12-14	cell culture	-
PXD000680	2	Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination	Homo sapiens (Human)	COMPLETE	2014-04-15	HeLa cell,HEK-293 cell

TSGGDHAPDSPSGENSPAPQGR

101

107

ProteomeXchange accession	Peptide frequency	Project Title	Species	Submission Type	Publication Date	Tissues	USI
PXD001333	1	Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC	Homo sapiens (Human)	PARTIAL	2015-04-23	HeLa cell	-
PXD001550	2	Human CRC cell line baseline phosphoproteomics	Homo sapiens (Human)	PARTIAL	2015-04-15	cell culture	-
PXD000680	1	Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination	Homo sapiens (Human)	COMPLETE	2014-04-15	HeLa cell,HEK-293 cell

LDDLCSSIIDGRFREQK

343

337

353

ProteomeXchange accession	Peptide frequency	Project Title	Species	Submission Type	Publication Date	Tissues	USI
PXD001060	1	Fe-IMAC column based phospho enrichment	Homo sapiens (Human)	PARTIAL	2015-08-19	Epithelial cell

Structures

Showing 5 results

PDB id

Chain

Method

Resolution

Stoichiometry

Interfacing Molecule/Chain

Complex Formation Significance Score (CSS)

P-sites

View Structure

4P0P

X-ray

2.8

0.8877626

343

Swiss-Prot position	PDB position	Residue	Secondary Structure	Conserved Scale	Accessible surface area	Buried surface area
343	343	SER	H	1.0	0.0	0.0
497	497	TYR	C	1.0	15.921035766601562	0.0
507	507	TYR	H	1.0	4.833610534667969	2.178687572479248

4P0Q

X-ray

2.85

1.0

343

Swiss-Prot position	PDB position	Residue	Secondary Structure	Conserved Scale	Accessible surface area	Buried surface area
343	343	SER	H	1.0	0.0	0.0
497	497	TYR	C	1.0	16.83915138244629	0.0
507	507	TYR	H	1.0	4.6032891273498535	2.178687572479248

2ZIX

X-ray

3.5

1.0

343

Swiss-Prot position	PDB position	Residue	Secondary Structure	Conserved Scale	Accessible surface area
343	343	SER	H	1.0	14.54230785369873
497	497	TYR	C	1.0	47.36084747314453
507	507	TYR	H	1.0	6.710906982421875

4P0S

X-ray

6.0

1.0

343

Swiss-Prot position	PDB position	Residue	Secondary Structure	Conserved Scale	Accessible surface area	Buried surface area
343	343	SER	H	1.0	0.33661335706710815	0.0
497	497	TYR	C	1.0	11.22136402130127	0.0
507	507	TYR	H	1.0	3.29764986038208	1.510514497756958

4P0R

X-ray

6.5

1.0

343

Swiss-Prot position	PDB position	Residue	Secondary Structure	Conserved Scale	Accessible surface area	Buried surface area
343	343	SER	H	1.0	0.0	0.0
497	497	TYR	C	1.0	29.90447425842285	0.0
507	507	TYR	C	1.0	5.513442516326904	1.757211446762085

Mutations

Showing 6 results

Swiss-Prot Position	Amino acid (Wild type)	Amino acid (Variant)	Variant Type
37	R	H	Polymorphism
115	S	F	Polymorphism
180	R	P	Polymorphism
189	L	F	Polymorphism
350	R	W	Polymorphism
481	Q	H	Polymorphism

Swiss-Prot Position

Amino acid (Wild type)

Amino acid (Variant)

Variant Type

Disease

Polymorphism

115

Polymorphism

180

Polymorphism

189

Polymorphism

350

Polymorphism

481

Polymorphism