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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 8 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
379 TYR PRIDE yes
386 THR PRIDE yes
388 SER PRIDE yes
401 SER PRIDE yes
406 SER PRIDE yes
446 SER PRIDE yes
477 SER UP, PRIDE Combined yes
707 SER PRIDE yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 14 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
379 378 385 2 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
386 386 402 1 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004415 1 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte
388 386 402 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD005366 1 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture
401 393 423 9 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 2 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
406 393 423 14 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD002436 1 Monitoring cellular phosphorylation signaling pathways into chromatin and down to the gene level Homo sapiens (Human) COMPLETE 2015-11-09 HeLa cell
406 403 423 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000680 2 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
406 403 416 4 4
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 20 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD003531 4 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD004452 3 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
PXD000680 3 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
446 444 453 3 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD002286 1 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 -
477 472 487 6 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
477 473 487 5 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 18 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD003531 7 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell
PXD006482 1 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney -
477 473 488 5 5
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004252 3 Modulating the selectivity of affinity absorbents to multi-phosphopeptides by a novel competitive substitution strategy Homo sapiens (Human) PARTIAL 2016-08-03 cell culture -
PXD006482 3 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney -
PXD005366 120 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
PXD000680 35 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -
477 475 488 3 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 5 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001333 4 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
477 475 487 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD002286 10 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 -
707 688 713 20 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon

Structures

Showing 0 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure

Mutations

Showing 124 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
18 R C Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
19 I F Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
21 A V Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
22 G A Polymorphism
25 I F Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
28 P L Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
29 A S Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
31 A C Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
32 I V Polymorphism
35 M K Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
37 E K Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
38 N K Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
41 D H Polymorphism
44 S F Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
54 G E Unclassified Colorectal cancer (CRC) [MIM:114500]
62 Q K Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
63 D E Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
64 N S Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
67 G W Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
68 I N Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
69 R K Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
77 C R Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
80 F V Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
84 K E Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
93 S G Polymorphism
98 G S Polymorphism
101 G D Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
102 E K Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
106 S R Unclassified Gastric cancer
107 I R Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
109 H Q Unclassified Gastric cancer
111 A P Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
116 T K Polymorphism
117 T R Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
126 Y N Polymorphism
128 A P Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
132 D H Disease Colorectal cancer (CRC) [MIM:114500]
155 L R Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
182 R K Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
185 V G Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
193 S P Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
213 V M Polymorphism
215 N S Polymorphism
216 I S Polymorphism
217 R G Polymorphism
219 I V Polymorphism
226 R L Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
234 E G Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
244 G V Unclassified Colorectal cancer (CRC) [MIM:114500]
247 S P Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
260 L F Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
264 H Y Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
265 R C Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
268 E G Disease Colorectal cancer (CRC) [MIM:114500]
282 A G Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
292 L P Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
295 S T Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
304 D V Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
309 P S Polymorphism
320 E D Polymorphism
321 S I Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
325 R Q Unclassified Colorectal cancer (CRC) [MIM:114500]
326 V A Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
329 H P Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
338 N S Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
379 Y C Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
384 V D Polymorphism
385 R P Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
389 R W Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
403 P S Polymorphism
406 S N Polymorphism
423 R T Polymorphism
441 A T Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
443 K Q Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
460 E A Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
472 R I Unclassified Colorectal cancer (CRC) [MIM:114500]
474 R W Polymorphism
485 D E Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
492 A T Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
506 V A Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
539 A D Polymorphism
542 Q L Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
549 L P Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
550 L P Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
551 N T Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
559 L R Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
565 I F Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
574 L P Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
578 E G Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
582 L V Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
585 L R Polymorphism
586 A P Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
588 L P Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
589 A D Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
601 D G Unclassified Colorectal cancer (CRC) [MIM:114500]
603 P R Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
607 L H Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
618 K R Disease Colorectal cancer (CRC) [MIM:114500]
619 A P Polymorphism
622 L H Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
623 A P Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
631 D A Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
635 N K Unclassified Gastric cancer
636 L P Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
640 P S Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
646 Y C Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
648 P S Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
654 P L Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
655 I V Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
656 F S Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
659 R Q Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
662 T P Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
666 W R Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
681 A T Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
687 R W Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
689 Q R Unclassified
716 V M Polymorphism
718 H Y Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
724 L M Disease Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
725 R H Polymorphism
729 L V Polymorphism
749 L P Disease Colorectal cancer (CRC) [MIM:114500]
751 K R Unclassified Hereditary non-polyposis colorectal cancer 2 (HNPCC2) [MIM:609310]
755 R W Polymorphism