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Search for the desired protein with Uniprot accession, protein name/keyword, ProteomeXchange ID or PDB id

Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 21 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
71 THR PRIDE yes
83 TYR PRIDE yes
409 TYR PRIDE
413 SER UP, PRIDE Combined
415 SER UP, PRIDE Combined
643 SER PRIDE yes
685 SER PRIDE yes
1016 SER UP, PRIDE Combined yes
1142 SER PRIDE yes
1158 SER PRIDE yes
1160 SER UP, PRIDE Combined yes
1255 SER PRIDE yes
1280 SER PRIDE yes
1352 SER PRIDE yes
1438 TYR PRIDE yes
1468 SER UP, PRIDE Similarity
1470 SER UP, PRIDE Combined
1479 TYR PRIDE yes
1675 TYR PRIDE yes
1792 SER PRIDE yes
1868 SER UP, PRIDE Combined yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 23 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
71 71 79 1 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
83 80 86 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD003198 1 Characterisation of pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling Homo sapiens (Human) PARTIAL 2016-06-09 pancreatic cell line
409 405 427 5 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 1 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell
413 405 427 9 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 1 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell -
PXD000612 4 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
PXD001550 1 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
415 405 427 11 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 2 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell
PXD000612 4 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001550 1 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
643 641 652 3 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD002436 1 Monitoring cellular phosphorylation signaling pathways into chromatin and down to the gene level Homo sapiens (Human) COMPLETE 2015-11-09 HeLa cell
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -
685 677 692 9 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD004415 1 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte
1016 1011 1019 6 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 25 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
PXD003531 6 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD004452 2 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
1142 1140 1154 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 10 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
1158 1155 1163 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD005366 1 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture
1160 1155 1163 6 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 55 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD003531 14 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD004452 2 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
1255 1250 1272 6 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 5 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004452 3 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
1280 1275 1288 6 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 4 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
1352 1350 1361 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000218 1 System-level analysis of cancer and stomal cell specific proteomes reveals extensive reprogramming of phosphorylation networks by tumor microenvironment Homo sapiens (Human),Mus musculus (Mouse) COMPLETE 2014-04-01 Epithelial cell, colon
1438 1431 1451 8 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD001060 10 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell
1468 1466 1482 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
1470 1466 1482 5 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
1470 1467 1482 4 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 9 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
1479 1467 1482 13 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 4 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
1675 1672 1678 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD006482 1 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney
1792 1792 1806 1 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
1792 1792 1798 1 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 6 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
1868 1856 1872 13 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI 
PXD000612 3 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture

Structures

Showing 13 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
5ZAK A EM 4.400000095367432 Monomer B 0.0 71, 83, 643, 685, 1016, 1352, 1675, 1868
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
71 71 THR H 1.0 22.851823806762695 0.0
83 83 TYR H 0.84 17.249404907226562 0.0
643 643 SER C 1.0 15.222466468811035 0.0
685 685 SER C 0.51 38.81520462036133 0.0
965 965 TYR C 1.0 49.84709548950195 0.0
1016 1016 SER H 1.0 63.088409423828125 0.0
1352 1352 SER C 1.0 57.91830825805664 0.0
1675 1675 TYR C 0.95 77.4696044921875 0.0
1868 1868 SER C 1.0 19.582151412963867 0.0
5ZAL A EM 4.699999809265137 Monomer C 0.0 71, 83, 643, 685, 1016, 1352, 1675, 1868
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
71 71 THR H 1.0 24.917577743530273 0.0
83 83 TYR H 0.84 41.85529708862305 0.0
643 643 SER C 1.0 11.470260620117188 0.0
685 685 SER C 0.51 50.029273986816406 0.0
965 965 TYR C 1.0 32.41355514526367 0.0
1016 1016 SER H 1.0 93.18781280517578 0.4920789301395416
1352 1352 SER C 1.0 50.036041259765625 0.0
1675 1675 TYR C 0.95 30.80522918701172 0.0
1868 1868 SER C 1.0 29.485708236694336 0.0
5ZAM A EM 5.699999809265137 Monomer C 0.0 71, 83, 643, 685, 1016, 1352, 1675, 1868
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
71 71 THR H 1.0 25.84067153930664 0.0
83 83 TYR H 0.84 49.50189971923828 0.0
643 643 SER C 1.0 22.60162353515625 0.0
685 685 SER C 0.51 51.155906677246094 0.0
965 965 TYR C 1.0 53.75670623779297 1.6687870025634766
1016 1016 SER H 1.0 76.98429107666016 36.239864349365234
1352 1352 SER C 1.0 38.908973693847656 0.0
1675 1675 TYR C 0.95 61.80120086669922 0.0
1868 1868 SER C 1.0 14.526275634765625 0.0
4NGD A X-ray 1.9600000381469727 4 [SO4]A:1101 0.5641672
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
965 955 TYR C 1.0 46.9229621887207 0.0
1016 1006 SER H 1.0 95.05069732666016 0.0
2EB1 A X-ray 2.0 2 C 0.41960695
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
1675 17 TYR C 0.95 31.166187286376953 0.0
4NGC A X-ray 2.0999999046325684 4 B 1.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
965 955 TYR C 1.0 38.60607147216797 6.812776565551758
1016 1005 SER H 1.0 95.90640258789062 70.06951904296875
4NGB A X-ray 2.25 4 B 1.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
965 955 TYR C 1.0 41.49179458618164 4.208284378051758
1016 1006 SER H 1.0 96.99703979492188 68.94912719726562
4NH5 A X-ray 2.549999952316284 4 B 1.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
965 955 TYR C 1.0 43.478763580322266 4.1357903480529785
4NH6 A X-ray 2.549999952316284 4 B 1.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
965 955 TYR C 1.0 41.73642349243164 3.3386929035186768
1016 1005 SER C 1.0 100.62769317626953 81.85726928710938
4NGG A X-ray 2.5999999046325684 8 B 0.64889044
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
965 955 TYR C 1.0 42.84550857543945 4.850985527038574
4NH3 A X-ray 2.619999885559082 4 B 1.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
965 955 TYR C 1.0 43.413780212402344 4.5174174308776855
1016 1006 SER H 1.0 94.62513732910156 65.19721221923828
4NGF A X-ray 3.0999999046325684 4 D 1.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
965 955 TYR C 1.0 50.468509674072266 4.572412014007568
1016 1006 SER H 1.0 85.53939819335938 0.0
4NHA A X-ray 3.4000000953674316 4 B 1.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
965 955 TYR C 1.0 48.59809112548828 5.68699836730957

Mutations

Showing 9 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
435 P L Unclassified
839 S F Disease Goiter multinodular 1, with or without Sertoli-Leydig cell tumors (MNG1) [MIM:138800]
1583 L R Disease Pleuropulmonary blastoma (PPB) [MIM:601200]
1705 E K Unclassified Non-epithelial ovarian tumor
1709 D N Unclassified Non-epithelial ovarian tumor
1713 D V Disease Global developmental delay, lung cysts, overgrowth, and Wilms tumor (GLOW) [MIM:618272]
1810 D Y Unclassified Non-epithelial ovarian tumor
1813 E Q Unclassified Non-epithelial ovarian tumor
1898 R G Unclassified