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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

FAK2_HUMAN : Protein-tyrosine kinase 2-beta

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PDB 
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Phospho-sites

Showing 19 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
307 SER PRIDE yes
361 SER UP, PRIDE Combined yes
375 SER UP, PRIDE Combined yes
418 TYR PRIDE yes
458 THR PRIDE yes
464 THR PRIDE yes
571 SER PRIDE yes
579 TYR UP, PRIDE Similarity
580 TYR UP, PRIDE Experimental
708 THR PRIDE yes
718 SER PRIDE yes
722 TYR UP, PRIDE Combined yes
778 SER PRIDE yes
789 SER PRIDE yes
819 TYR UP, PRIDE Combined yes
834 TYR UP, PRIDE Combined yes
842 THR UP, PRIDE Combined yes
849 TYR UP, PRIDE Combined
881 TYR UP Experimental

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 27 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
QIRSIR 307 304 309 4 1
LQGEHQGSLIIHPR 361 354 367 8 1
RNSLPQIPMLNLEARR 375 373 388 3 1
RNSLPQIPMLNLEAR 375 373 387 3 8
NSLPQIPMLNLEAR 375 374 387 2 2
RPGGPQYGIAR 418 412 422 7 1
TCKKDCTLDNK 458 458 468 1 1
KDCTLDNKEK 464 461 470 4 1
DCTLDNK 464 462 468 3 1
LGDFGLSR 571 565 572 7 2
YIEDEDYYKASVTRLPIK 579 573 590 7 2
YIEDEDYYKASVTR 579 573 586 7 1
YIEDEDYYK 579 573 581 7 1
YIEDEDYYKASVTRLPIK 580 573 590 8 2
YIEDEDYYK 580 573 581 8 1
YIEDEDYYKASVTR 580 573 586 8 1
ILEPTAFQEPPPK 708 704 716 5 1
ILEPTAFQEPPPKPSRPK 718 704 721 15 1
YRPPPQTNLLAPK 722 722 734 1 1
RHSMREEDFIQPSSR 778 776 790 3 4
EEDFIQPSSR 789 781 790 9 1
QMVEDYQWLR 819 814 823 6 1
SLDPMVYMNDK 834 828 838 7 1
SPLTPEK 842 839 845 4 3
SPLTPEKEVGYLEFTGPPQKPPR 842 839 861 4 1
SPLTPEKEVGYLEFTGPPQKPPR 849 839 861 11 1
EVGYLEFTGPPQKPPR 849 846 861 4 2

Structures

Showing 21 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
3CC6 A X-ray 1.6 Monomer [MG]A:701 0.07157021 418, 458, 464, 571
3FZT A X-ray 1.95 Monomer [4JZ]A:999 0.0 458, 464, 571
5TO8 A X-ray 1.98 Monomer [7FM]A:701 0.1 458, 464, 571
4H1M A X-ray 1.99 Monomer [0YJ]A:701 0.0 458, 464, 571
3H3C A X-ray 2.0 Monomer [SO4]A:1 0.022847384 418, 458, 464
4H1J A X-ray 2.0 Monomer [0YH]A:701 0.0 458, 464, 571
3FZO A X-ray 2.2 Monomer A 0.0 458, 464, 571
3FZR A X-ray 2.7 Monomer [PO4]A:1 0.070011295 458, 464, 571
3ET7 A X-ray 2.7 Monomer [PO4]A:1001 0.070913546 458, 464, 571
3FZS A X-ray 1.75 Monomer [B96]A:999 0.1 458, 464
3FZP A X-ray 2.1 Monomer [SO4]A:2 0.04643789 458, 464
4EKU A X-ray 3.25 2 A 1.0 307, 361
4XEK A X-ray 1.79 2 C 1.0 881
4XEV A X-ray 2.01 2 C 1.0 881
5TOB A X-ray 2.12 Monomer [YAM]A:701 0.1 458
4XEF A X-ray 2.5 6 B 1.0 881
3GM3 A X-ray 2.6 Monomer A 0.0 881
3GM2 A X-ray 2.71 4 A 0.6027031 881
3GM1 A X-ray 2.95 3 E 1.0 881
3U3F A X-ray 3.1 3 E 1.0 881
4R32 A X-ray 3.7 12 C 1.0 881

Mutations

Showing 5 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
359 Q E Polymorphism
698 R H Polymorphism
808 L P Polymorphism
838 K T Polymorphism
970 E K Polymorphism