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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 18 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
93 PhosphoS UP, PRIDE Combined
97 PhosphoT UP, PRIDE Combined
143 PhosphoS UP, PRIDE Experimental
147 PhosphoS UP, PRIDE Combined
151 PhosphoS PRIDE yes
179 PhosphoS PRIDE yes
181 PhosphoT PRIDE yes
220 PhosphoS PRIDE yes
288 PhosphoS PRIDE
289 PhosphoT PRIDE
317 PhosphoS PRIDE yes
387 PhosphoS PRIDE yes
389 PhosphoS PRIDE yes
458 PhosphoS PRIDE
468 PhosphoS PRIDE
620 PhosphoS PRIDE
621 PhosphoS PRIDE
624 PhosphoT PRIDE

3D structure is not available

Display Settings

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 20 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
93 90 99 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 3 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
97 90 99 8 3
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 14 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
PXD005366 1 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture -
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
143 135 157 9 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
143 142 157 2 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
147 135 157 13 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
147 142 157 6 10
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD004252 1 Modulating the selectivity of affinity absorbents to multi-phosphopeptides by a novel competitive substitution strategy Homo sapiens (Human) PARTIAL 2016-08-03 cell culture -
PXD000612 8 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001546 3 Reproducibility of label-free single-shot phosphoproteomics applied to CRC cell lines Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD004415 10 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte -
PXD004940 1 Performance of the Orbitrap Fusion Lumos Tribrid in single-shot analyses of human samples Homo sapiens (Human) PARTIAL 2017-03-09 HeLa cell -
PXD003531 1 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD005366 45 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture -
PXD001550 28 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture -
PXD004452 6 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -
PXD000680 31 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
151 146 157 6 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
179 158 183 22 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD002286 6 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 - -
PXD001550 12 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture
181 158 183 24 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD001550 2 Human CRC cell line baseline phosphoproteomics Homo sapiens (Human) PARTIAL 2015-04-15 cell culture
220 215 229 6 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
288 275 291 14 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 11 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001333 2 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell
289 275 291 15 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 13 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
PXD001333 2 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell -
317 312 320 6 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
387 386 392 2 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
389 386 392 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 2 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
458 456 470 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 2 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
468 456 470 13 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 2 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
620 619 626 2 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
621 619 626 3 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
624 619 626 6 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture

Structures

Showing 18 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
2WB8 A X-ray 2.1500000953674316 Monomer A 0.0 458, 468, 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
458 458 SER H NaN 52.997432708740234 0.0
468 468 SER C NaN 104.25897979736328 0.0
620 620 SER C NaN 51.041114807128906 0.0
621 621 SER C NaN 16.284456253051758 0.0
624 624 THR H NaN 5.564970970153809 0.0
6G35 A X-ray 1.5499999523162842 Monomer [NA]A:801 0.023543024 468, 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
468 468 SER C NaN 96.88233184814453 0.0
620 620 SER C NaN 65.2030258178711 0.0
621 621 SER C NaN 11.159533500671387 0.0
624 624 THR H NaN 9.158792495727539 0.0
4QTC A X-ray 1.399999976158142 Monomer [MPD]A:801 0.06619235 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 620 SER C NaN 63.0588264465332 0.0
621 621 SER C NaN 10.366223335266113 0.0
624 624 THR H NaN 6.76899528503418 0.0
6G3A A X-ray 1.4299999475479126 Monomer [PO4]A:807 0.13164262 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 620 SER C NaN 58.462833404541016 0.0
621 621 SER C NaN 11.120942115783691 0.0
624 624 THR H NaN 7.878846168518066 0.0
6G39 A X-ray 1.4500000476837158 Monomer [NA]A:801 0.100045994 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 620 SER C NaN 61.97850799560547 0.0
621 621 SER C NaN 11.840332984924316 0.0
624 624 THR H NaN 9.863574981689453 0.0
6G38 A X-ray 1.4700000286102295 Monomer [PO4]A:803 0.48617804 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 620 SER C NaN 59.864036560058594 0.0
621 621 SER C NaN 10.761391639709473 0.0
624 624 THR H NaN 8.98659896850586 0.0
6G37 A X-ray 1.4800000190734863 Monomer [PO4]A:800 0.22015132 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 620 SER C NaN 60.817115783691406 0.0
621 621 SER C NaN 9.138671875 0.0
624 624 THR H NaN 8.568397521972656 0.0
5HTC A X-ray 1.5 2 [NA]A:803 0.043358404 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 620 SER C NaN 58.43874740600586 0.0
621 621 SER C NaN 11.45599365234375 0.0
624 624 THR H NaN 9.431838035583496 0.0
5HTB A X-ray 1.7000000476837158 2 [NA]A:802 0.3511489 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 620 SER C NaN 58.79770278930664 0.0
621 621 SER C NaN 10.32674789428711 0.0
624 624 THR H NaN 10.087491989135742 0.0
2VUW A X-ray 1.7999999523162842 Monomer [MPD]A:1803 0.06980842 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 620 SER C NaN 58.94334030151367 0.0
621 621 SER C NaN 7.795112609863281 0.0
624 624 THR H NaN 7.9139604568481445 0.0
3F2N A X-ray 1.7999999523162842 Monomer [IZZ]A:800 0.11053029 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 620 SER C NaN 53.63385009765625 0.0
621 621 SER C NaN 9.5532808303833 0.0
624 624 THR H NaN 7.435091018676758 0.0
3DLZ A X-ray 1.850000023841858 Monomer [MG]A:901 0.10451177 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 620 SER C NaN 51.548988342285156 0.0
621 621 SER C NaN 16.7420654296875 0.0
624 624 THR H NaN 5.4655303955078125 0.0
4OUC A X-ray 1.899999976158142 2 [NA]A:801 0.24996416 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 620 SER C NaN 49.827701568603516 0.0
621 621 SER C NaN 17.165571212768555 0.0
624 624 THR H NaN 5.836882591247559 0.0
3IQ7 A X-ray 2.0 Monomer [PO4]A:1 0.17915031 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 620 SER C NaN 64.75328063964844 0.0
621 621 SER C NaN 8.1033353805542 0.0
624 624 THR H NaN 6.942139625549316 0.0
3E7V A X-ray 2.0 Monomer A 0.0 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 620 SER C NaN 63.468994140625 0.0
621 621 SER C NaN 10.202380180358887 0.0
624 624 THR H NaN 7.3134894371032715 0.0
3FMD A X-ray 2.0 Monomer A 0.0 620, 621, 624
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 620 SER C NaN 47.988521575927734 0.0
621 621 SER C NaN 10.544464111328125 0.0
624 624 THR H NaN 6.132462501525879 0.0
6G36 A X-ray 1.4600000381469727 Monomer [NA]A:407 0.03081557
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
468 27 SER C NaN 95.56002807617188 0.0
620 179 SER C NaN 58.33201217651367 0.0
621 180 SER C NaN 8.199836730957031 0.0
624 183 THR H NaN 8.80145263671875 0.0
6G34 A X-ray 1.7599999904632568 Monomer [PO4]A:404 0.17963825
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
620 179 SER C NaN 60.45112609863281 0.0
621 180 SER C NaN 6.878157615661621 0.0
624 183 THR H NaN 8.035491943359375 0.0

Mutations

Showing 10 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
76 V E Polymorphism
82 R C Polymorphism
145 R H Polymorphism
204 G D Polymorphism
283 G S Polymorphism
301 Q L Polymorphism
328 I T Polymorphism
378 V A Polymorphism
422 N D Polymorphism
706 M V Polymorphism