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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 4 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
130 PhosphoS UP, PRIDE Combined yes
145 PhosphoT UP Experimental
146 PhosphoS UP Experimental
160 PhosphoS UP Experimental

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 2 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
130 123 140 8 8
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD001060 4 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell -
PXD000612 6 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD000474 1 Simulated phosphopeptide spectral library for confident site localization Homo sapiens (Human) PARTIAL 2015-03-17 HeLa cell -
PXD001333 2 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell -
PXD002286 1 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 - -
PXD005366 14 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture
PXD001374 8 Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling Homo sapiens (Human) PARTIAL 2015-08-24 HeLa cell -
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -
130 123 141 8 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 7 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001333 2 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell

Structures

Showing 5 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
5E0U D X-ray 1.9299999475479126 6 A 1.0 145, 146, 160
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
145 145 THR C 0.92 69.57357025146484 42.949398040771484
146 146 SER C 0.78 62.09832000732422 31.71014404296875
160 160 SER C 0.35 154.05340576171875 116.91974639892578
4RJF B X-ray 2.009999990463257 2 A 1.0 145, 146, 160
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
145 145 THR C 0.92 65.11969757080078 40.48187255859375
146 146 SER C 0.78 57.56598663330078 32.20667266845703
160 160 SER C 0.35 157.68165588378906 121.42825317382812
1AXC B X-ray 2.5999999046325684 6 A 1.0 145, 146, 160
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
145 145 THR C 0.92 73.7869644165039 48.31495666503906
146 146 SER C 0.78 55.72766876220703 30.39402961730957
160 160 SER C 0.35 152.22409057617188 124.23527526855469
2ZVV X X-ray 2.0 6 A 0.49398845 145, 146
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
145 145 THR C 0.92 77.8966064453125 48.85599136352539
146 146 SER C 0.78 56.646217346191406 25.311195373535156
2ZVW I X-ray 2.5 6 A 1.0 145, 146
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
145 145 THR C 0.92 72.73562622070312 46.88875198364258
146 146 SER C 0.78 56.25868225097656 24.284643173217773

Mutations

Showing 3 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
4 P L Polymorphism
31 S R Polymorphism
63 F L Polymorphism