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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 4 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
66 PhosphoS PRIDE yes
93 PhosphoS PRIDE yes
638 PhosphoS PRIDE
640 PhosphoT PRIDE

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 6 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
66 64 84 3 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD003531 8 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell -
PXD006482 1 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney
93 90 96 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD001060 1 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell
638 635 649 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
638 635 660 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
640 635 649 6 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
640 635 660 6 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
PXD004452 2 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon -

Structures

Showing 9 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
5GGF A X-ray 2.490000009536743 Monomer B 0.0 638, 640
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
248 248 SER C 0.93 67.22041320800781 0.0
638 638 SER C 0.32 104.7119140625 0.0
640 640 THR C 0.86 105.6059341430664 0.0
5GGI A X-ray 2.5999999046325684 2 [PO4]A:703 0.036479734 638, 640
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
638 638 SER C 0.32 105.2341537475586 0.0
640 640 THR C 0.86 108.08014678955078 0.0
5GGG A X-ray 3.0 Monomer A 0.0 638, 640
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
248 248 SER C 0.93 58.79979705810547 0.0
638 638 SER C 0.32 106.97611236572266 0.0
640 640 THR C 0.86 99.253662109375 0.0
5GGN A X-ray 1.2100000381469727 Monomer [LEC]B:301 0.1
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
248 248 SER C 0.93 105.37512969970703 18.0499210357666
5GGL A X-ray 1.2699999809265137 Monomer [6ZC]B:301 0.1
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
248 248 SER C 0.93 83.85164642333984 20.17584991455078
5GGK A X-ray 1.2999999523162842 Monomer B 0.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
248 248 SER C 0.93 101.22338104248047 0.0
5XFC A X-ray 1.399999976158142 Monomer B 0.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
248 248 SER C 0.93 109.77737426757812 0.0
5GGJ A X-ray 1.4199999570846558 Monomer B 0.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
248 248 SER C 0.93 105.63096618652344 0.0
5GGO A X-ray 1.5 Monomer B 0.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
248 248 SER C 0.93 105.03614044189453 9.417963027954102

Mutations

Showing 22 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
120 L R Disease Retinitis pigmentosa 76 (RP76) [MIM:617123]
156 E K Disease Retinitis pigmentosa 76 (RP76) [MIM:617123]
176 T P Disease Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A3 (MDDGA3) [MIM:253280]
198 S R Disease Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A3 (MDDGA3) [MIM:253280]
223 E K Disease Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A3 (MDDGA3) [MIM:253280]
250 E V Polymorphism
265 R H Unclassified Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A3 (MDDGA3) [MIM:253280]
269 C Y Disease Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A3 (MDDGA3) [MIM:253280]
287 I S Disease Retinitis pigmentosa 76 (RP76) [MIM:617123]
311 R Q Disease Muscular dystrophy-dystroglycanopathy congenital with mental retardation B3 (MDDGB3) [MIM:613151]
367 R H Disease Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A3 (MDDGA3) [MIM:253280]
425 W S Disease Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A3 (MDDGA3) [MIM:253280]
427 D H Disease Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A3 (MDDGA3) [MIM:253280]
442 R C Disease Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A3 (MDDGA3) [MIM:253280]
490 C Y Disease Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A3 (MDDGA3) [MIM:253280]
493 P R Disease Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A3 (MDDGA3) [MIM:253280]
502 G A Disease Retinitis pigmentosa 76 (RP76) [MIM:617123]
504 V I Polymorphism
550 S N Disease Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A3 (MDDGA3) [MIM:253280]
556 D N Disease Muscular dystrophy-dystroglycanopathy limb-girdle C3 (MDDGC3) [MIM:613157]
605 R P Disease Muscular dystrophy-dystroglycanopathy congenital with mental retardation B3 (MDDGB3) [MIM:613151]
623 M V Polymorphism