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Phospho-sites

Showing 3 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
77 PhosphoY PRIDE yes
92 PhosphoT PRIDE yes
295 PhosphoS PRIDE yes

3D structure is not available

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 3 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
77 74 85 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
92 86 96 7 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD003660 7 Early Signaling Dynamics of EGFR Homo sapiens (Human) COMPLETE 2016-06-24 Epithelial cell, cell culture
295 262 297 34 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD004415 1 Quantitative phosphoproteome analysis of cisplatin-induced apoptosis in Jurkat T cells Homo sapiens (Human) COMPLETE 2017-05-11 T lymphocyte

Structures

Showing 17 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
5FII A X-ray 1.7999999523162842 2 C 1.0 77, 92
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
77 77 TYR E 0.95 82.26810455322266 53.087257385253906
92 92 THR H 0.32 91.40248107910156 0.0
1J8U A X-ray 1.5 Monomer [FE2]A:428 0.07823878 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 14.200674057006836 0.0
1J8T A X-ray 1.7000000476837158 Monomer [FE2]A:428 0.1 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 13.736773490905762 0.0
1DMW A X-ray 2.0 Monomer [FE]A:425 0.077719994 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 13.378486633300781 0.0
1MMK A X-ray 2.0 Monomer [SO4]A:429 0.04206279 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 14.940428733825684 0.0
1MMT A X-ray 2.0 Monomer [SO4]A:428 0.043543752 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 15.570930480957031 0.0
4PAH A X-ray 2.0 Monomer [FE]A:425 0.050820556 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 11.807112693786621 0.0
1PAH A X-ray 2.0 Monomer [FE]A:425 0.1 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 12.626803398132324 0.0
3PAH A X-ray 2.0 Monomer [FE]A:425 0.080251016 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 13.48878002166748 0.0
5PAH A X-ray 2.0999999046325684 Monomer [FE]A:425 0.071685135 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER H 0.96 12.231112480163574 0.0
1TDW A X-ray 2.0999999046325684 Monomer [FE]A:425 0.1 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 12.987600326538086 0.0
1LRM A X-ray 2.0999999046325684 Monomer [FE]A:428 0.07534009 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER H 0.96 13.731866836547852 0.0
4ANP A X-ray 2.109999895095825 Monomer [3QI]A:1427 0.045208532 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 11.825846672058105 0.0
6PAH A X-ray 2.1500000953674316 Monomer [FE]A:425 0.1 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 14.479133605957031 0.0
1TG2 A X-ray 2.200000047683716 Monomer [FE]A:425 0.076268196 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 9.81718921661377 0.0
1KW0 A X-ray 2.5 Monomer [FE2]A:428 0.06632385 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 13.491850852966309 0.0
2PAH A X-ray 3.0999999046325684 4 [FE]A:453 0.58118373 295
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
295 295 SER C 0.96 14.570683479309082 0.0

Mutations

Showing 158 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
16 S P Disease Phenylketonuria (PKU) [MIM:261600]
20 Q L Disease Hyperphenylalaninemia (HPA) [MIM:261600]
39 F L Disease Hyperphenylalaninemia (HPA) [MIM:261600]
40 S L Disease Phenylketonuria (PKU) [MIM:261600]
41 L F Disease Phenylketonuria (PKU) [MIM:261600]
42 K I Disease Phenylketonuria (PKU) [MIM:261600]
45 V A Disease Phenylketonuria (PKU) [MIM:261600]
46 G S Disease Phenylketonuria (PKU) [MIM:261600]
47 A V Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
48 L S Disease Phenylketonuria (PKU) [MIM:261600]
53 R H Disease Phenylketonuria (PKU) [MIM:261600]
55 F L Disease Hyperphenylalaninemia (HPA) [MIM:261600]
56 E D Disease Phenylketonuria (PKU) [MIM:261600]
61 N D Disease Phenylketonuria (PKU) [MIM:261600]
62 L P Disease Phenylketonuria (PKU) [MIM:261600]
65 I V Disease Phenylketonuria (PKU) [MIM:261600]
67 S P Disease Phenylketonuria (PKU) [MIM:261600]
68 R S Disease Phenylketonuria (PKU) [MIM:261600]
76 E A Disease Phenylketonuria (PKU) [MIM:261600]
84 D Y Disease Phenylketonuria (PKU) [MIM:261600]
87 S R Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
92 T I Disease Phenylketonuria (PKU) [MIM:261600]
98 L S Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
104 A D Disease Phenylketonuria (PKU) [MIM:261600]
110 S C Disease Hyperphenylalaninemia (HPA) [MIM:261600]
121 F L Disease Hyperphenylalaninemia (HPA) [MIM:261600]
124 T I Disease Phenylketonuria (PKU) [MIM:261600]
129 D Y Disease Phenylketonuria (PKU) [MIM:261600]
143 D G Disease Phenylketonuria (PKU) [MIM:261600]
145 D V Disease Phenylketonuria (PKU) [MIM:261600]
146 H Y Disease Phenylketonuria (PKU) [MIM:261600]
148 G S Disease Phenylketonuria (PKU) [MIM:261600]
151 D H Disease Phenylketonuria (PKU) [MIM:261600]
154 Y N Disease Phenylketonuria (PKU) [MIM:261600]
155 R P Disease Phenylketonuria (PKU) [MIM:261600]
157 R S Disease Phenylketonuria (PKU) [MIM:261600]
158 R Q Disease Phenylketonuria (PKU) [MIM:261600]
160 Q P Disease Phenylketonuria (PKU) [MIM:261600]
161 F S Disease Phenylketonuria (PKU) [MIM:261600]
164 I T Disease Phenylketonuria (PKU) [MIM:261600]
167 N S Disease Hyperphenylalaninemia (HPA) [MIM:261600]
169 R H Disease Phenylketonuria (PKU) [MIM:261600]
170 H R Disease Phenylketonuria (PKU) [MIM:261600]
171 G R Disease Phenylketonuria (PKU) [MIM:261600]
173 P T Disease Phenylketonuria (PKU) [MIM:261600]
174 I V Disease Phenylketonuria (PKU) [MIM:261600]
175 P A Disease Phenylketonuria (PKU) [MIM:261600]
176 R P Disease Phenylketonuria (PKU) [MIM:261600]
177 V M Disease Hyperphenylalaninemia (HPA) [MIM:261600]
178 E G Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
183 E Q Disease Phenylketonuria (PKU) [MIM:261600]
190 V A Disease Phenylketonuria (PKU) [MIM:261600]
194 L P Disease Phenylketonuria (PKU) [MIM:261600]
196 S Y Disease Hyperphenylalaninemia (HPA) [MIM:261600]
201 H Y Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
204 Y C Disease Phenylketonuria (PKU) [MIM:261600]
205 E A Disease Phenylketonuria (PKU) [MIM:261600]
206 Y D Disease Phenylketonuria (PKU) [MIM:261600]
207 N S Disease Phenylketonuria (PKU) [MIM:261600]
211 P T Disease Phenylketonuria (PKU) [MIM:261600]
212 L P Disease Phenylketonuria (PKU) [MIM:261600]
213 L P Disease Phenylketonuria (PKU) [MIM:261600]
217 C G Disease Phenylketonuria (PKU) [MIM:261600]
218 G V Disease Phenylketonuria (PKU) [MIM:261600]
221 E G Disease Phenylketonuria (PKU) [MIM:261600]
222 D V Disease Phenylketonuria (PKU) [MIM:261600]
224 I M Disease Phenylketonuria (PKU) [MIM:261600]
225 P T Disease Phenylketonuria (PKU) [MIM:261600]
226 Q H Disease Phenylketonuria (PKU) [MIM:261600]
230 V I Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
231 S P Disease Phenylketonuria (PKU) [MIM:261600]
233 F L Disease Phenylketonuria (PKU) [MIM:261600]
238 T P Disease Phenylketonuria (PKU) [MIM:261600]
239 G S Disease Phenylketonuria (PKU) [MIM:261600]
240 F S Disease Phenylketonuria (PKU) [MIM:261600]
241 R C Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
242 L F Disease Phenylketonuria (PKU) [MIM:261600]
243 R Q Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
244 P L Disease Phenylketonuria (PKU) [MIM:261600]
245 V A Disease Phenylketonuria (PKU) [MIM:261600]
246 A D Disease Phenylketonuria (PKU) [MIM:261600]
247 G V Disease Phenylketonuria (PKU) [MIM:261600]
248 L P Disease Phenylketonuria (PKU) [MIM:261600]
249 L F Disease Phenylketonuria (PKU) [MIM:261600]
252 R W Disease Phenylketonuria (PKU) [MIM:261600]
255 L S Disease Phenylketonuria (PKU) [MIM:261600]
257 G C Disease Phenylketonuria (PKU) [MIM:261600]
259 A V Disease Phenylketonuria (PKU) [MIM:261600]
261 R Q Disease Phenylketonuria (PKU) [MIM:261600]
263 F L Disease Phenylketonuria (PKU) [MIM:261600]
264 H L Disease Phenylketonuria (PKU) [MIM:261600]
265 C G Disease Phenylketonuria (PKU) [MIM:261600]
269 I L Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
270 R K Disease Phenylketonuria (PKU) [MIM:261600]
271 H Y Disease Phenylketonuria (PKU) [MIM:261600]
273 S F Disease Phenylketonuria (PKU) [MIM:261600]
274 K E Polymorphism
275 P L Disease Phenylketonuria (PKU) [MIM:261600]
276 M V Disease Phenylketonuria (PKU) [MIM:261600]
277 Y C Disease Phenylketonuria (PKU) [MIM:261600]
278 T A Disease Phenylketonuria (PKU) [MIM:261600]
280 E K Disease Phenylketonuria (PKU) [MIM:261600]
281 P L Disease Phenylketonuria (PKU) [MIM:261600]
282 D N Disease Phenylketonuria (PKU) [MIM:261600]
283 I N Disease Phenylketonuria (PKU) [MIM:261600]
290 H Y Disease Phenylketonuria (PKU) [MIM:261600]
297 R H Disease Phenylketonuria (PKU) [MIM:261600]
299 F C Disease Phenylketonuria (PKU) [MIM:261600]
300 A S Disease Hyperphenylalaninemia (HPA) [MIM:261600]
303 S P Disease Phenylketonuria (PKU) [MIM:261600]
304 Q R Disease Phenylketonuria (PKU) [MIM:261600]
306 I V Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
309 A D Disease Phenylketonuria (PKU) [MIM:261600]
310 S F Disease Phenylketonuria (PKU) [MIM:261600]
311 L P Disease Phenylketonuria (PKU) [MIM:261600]
314 P S Disease Hyperphenylalaninemia (HPA) [MIM:261600]
318 I T Disease Phenylketonuria (PKU) [MIM:261600]
322 A V Disease Phenylketonuria (PKU) [MIM:261600]
325 Y C Disease Phenylketonuria (PKU) [MIM:261600]
330 E D Disease Phenylketonuria (PKU) [MIM:261600]
331 F L Disease Phenylketonuria (PKU) [MIM:261600]
333 L F Disease Phenylketonuria (PKU) [MIM:261600]
334 C S Disease Phenylketonuria (PKU) [MIM:261600]
337 G V Disease Phenylketonuria (PKU) [MIM:261600]
338 D Y Disease Phenylketonuria (PKU) [MIM:261600]
341 K R Disease Phenylketonuria (PKU) [MIM:261600]
342 A T Disease Phenylketonuria (PKU) [MIM:261600]
343 Y C Disease Phenylketonuria (PKU) [MIM:261600]
344 G R Disease Phenylketonuria (PKU) [MIM:261600]
345 A S Disease Phenylketonuria (PKU) [MIM:261600]
347 L F Disease Phenylketonuria (PKU) [MIM:261600]
348 L V Disease Phenylketonuria (PKU) [MIM:261600]
349 S P Disease Phenylketonuria (PKU) [MIM:261600]
350 S T Disease Phenylketonuria (PKU) [MIM:261600]
357 C G Disease Phenylketonuria (PKU) [MIM:261600]
362 P T Disease Phenylketonuria (PKU) [MIM:261600]
366 P H Disease Phenylketonuria (PKU) [MIM:261600]
372 T S Disease Phenylketonuria (PKU) [MIM:261600]
377 Y C Disease Phenylketonuria (PKU) [MIM:261600]
380 T M Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
386 Y C Disease Phenylketonuria (PKU) [MIM:261600]
387 Y H Disease Phenylketonuria (PKU) [MIM:261600]
388 V M Disease Phenylketonuria (PKU) [MIM:261600]
390 E G Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
394 D H Disease Phenylketonuria (PKU) [MIM:261600]
395 A P Disease Phenylketonuria (PKU) [MIM:261600]
403 A V Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
407 P S Disease Phenylketonuria (PKU) [MIM:261600]
408 R W Disease Phenylketonuria (PKU) [MIM:261600]
410 F S Disease Phenylketonuria (PKU) [MIM:261600]
413 R P Disease Non-phenylketonuria hyperphenylalaninemia (Non-PKU HPA) [MIM:261600]
414 Y C Disease Phenylketonuria (PKU) [MIM:261600]
415 D N Disease Phenylketonuria (PKU) [MIM:261600]
417 Y H Disease Phenylketonuria (PKU) [MIM:261600]
418 T P Disease Phenylketonuria (PKU) [MIM:261600]
421 I S Disease Phenylketonuria (PKU) [MIM:261600]
430 L P Disease Phenylketonuria (PKU) [MIM:261600]
447 A D Disease Phenylketonuria (PKU) [MIM:261600]