Welcome to Scop3P

Search for the desired protein with Uniprot accession, protein name/keyword, ProteomeXchange ID or PDB id

  • Zoom in and zoom out (both with mouse and buttons on the right top corner) to see modificationson the protein
  • Slide the chart to see other modifications (both with mouse and buttons on the right topcorner)
  • Hover on the modification to see more information and position on the structure.
PDB 
 AlphaFold
Phospho-sites

Showing 3 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
88 PhosphoY PRIDE
94 PhosphoT PRIDE
195 PhosphoS PRIDE yes

3D structure is not available

Display Settings

Hover over to see the values, zoom (in/out) or drag by using the mouse pointer.

Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 3 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
88 85 106 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
94 85 106 10 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
195 193 199 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD006482 1 Identification of Missing Proteins in the Phosphoproteome of Kidney Cancer Homo sapiens (Human) COMPLETE 2017-09-01 kidney

Structures

Showing 1 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
3OAI A X-ray 2.0999999046325684 Monomer [MAL]A:1122 0.1
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
88 1059 TYR E 1 111.03131103515625 0.0
94 1065 THR C 0.74 104.91276550292969 0.0

Mutations

Showing 65 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
30 I M Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
32 V F Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
34 T I Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
35 D Y Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
39 H P Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
44 S F Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
51 S F Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
54 S P Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
56 E K Unclassified
58 V F Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
60 D H Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
61 D G Polymorphism
62 I F Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
63 S F Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
65 T A Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
68 Y C Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
75 D V Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
78 S L Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
81 H R Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
82 Y C Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
89 I N Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
90 D E Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
92 V M Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
93 G E Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
96 K E Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
97 E V Disease Charcot-Marie-Tooth disease 2J (CMT2J) [MIM:607736]
98 R P Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
99 I T Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
101 W C Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
103 G E Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
109 D N Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
110 G D Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
112 I T Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
113 V F Polymorphism
114 I T Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
116 N H Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
118 D N Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
119 Y C Polymorphism
122 N S Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
123 G C Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
124 T M Disease Charcot-Marie-Tooth disease 2J (CMT2J) [MIM:607736]
127 C Y Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
128 D N Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
130 K R Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
131 N K Disease Roussy-Levy syndrome (ROULS) [MIM:180800]
132 P L Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
134 D G Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
135 I L Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
136 V E Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
137 G S Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
138 K N Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
139 T N Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
140 S T Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
143 T M Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
145 Y S Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
146 V F Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
162 I M Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
163 G R Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
167 G R Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
170 L R Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
221 A T Disease Dejerine-Sottas syndrome (DSS) [MIM:145900]
224 D Y Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
227 R S Disease Charcot-Marie-Tooth disease 1B (CMT1B) [MIM:118200]
236 K E Disease Charcot-Marie-Tooth disease 2I (CMT2I) [MIM:607677]
244 R L Polymorphism