Welcome to Scop3P

Search for the desired protein with Uniprot accession, protein name/keyword, ProteomeXchange ID or PDB id

Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

  • Zoom in and zoom out (both with mouse and buttons on the right top corner) to see modificationson the protein
  • Slide the chart to see other modifications (both with mouse and buttons on the right topcorner)
  • Hover on the modification to see more information and position on the structure.
PDB 
 AlphaFold
Phospho-sites

Showing 10 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
285 PhosphoT PRIDE yes
869 PhosphoT PRIDE
871 PhosphoT PRIDE
893 PhosphoS PRIDE yes
1005 PhosphoS PRIDE
1017 PhosphoS PRIDE
1161 PhosphoS PRIDE
1188 PhosphoT PRIDE
1252 PhosphoT PRIDE yes
1301 PhosphoT PRIDE yes

3D structure is not available

Display Settings

Hover over to see the values, zoom (in/out) or drag by using the mouse pointer.

Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 10 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
285 276 290 10 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
869 856 875 14 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD001333 1 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell -
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
871 856 875 16 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD001333 1 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell -
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
893 893 899 1 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
1005 988 1023 18 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
1017 988 1023 30 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
1161 1160 1194 2 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
1188 1160 1194 29 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
1252 1250 1268 3 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
1301 1295 1305 7 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD004452 1 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon

Structures

Showing 0 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure

Mutations

Showing 105 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
4 P H Unclassified
9 A E Unclassified
21 P S Unclassified
61 G D Polymorphism
64 R W Polymorphism
78 A T Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
90 A T Unclassified
125 E K Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
129 G E Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
158 A V Polymorphism
207 G R Polymorphism
265 R G Polymorphism
281 K E Polymorphism
317 S R Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
319 I V Polymorphism
355 L R Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
364 T R Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
370 N D Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
382 R W Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
391 R G Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
392 K N Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
398 S G Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
411 N K Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
417 V M Polymorphism
419 R Q Unclassified
440 C G Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
455 A P Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
463 L H Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
495 L H Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
497 N K Polymorphism
514 V I Polymorphism
518 R Q Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
535 S P Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
551 F S Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
568 F S Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
590 S F Disease Arterial calcification of infancy, generalized, 2 (GACI2) [MIM:614473]
594 A V Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
600 R C Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
605 L P Unclassified
614 V A Polymorphism
632 H Q Polymorphism
663 G C Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
665 V A Polymorphism
673 L P Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
677 L P Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
698 Q P Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
699 E D Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
709 E G Unclassified
724 R L Polymorphism
726 L P Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
742 I V Polymorphism
751 M K Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
755 G R Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
760 R W Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
765 R Q Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
766 A D Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
777 D N Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
807 R W Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
810 V M Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
811 T M Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
820 A P Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
834 M T Unclassified
848 M V Polymorphism
881 R S Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
944 T I Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
946 L I Polymorphism
948 L P Unclassified
950 A T Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
953 L H Polymorphism
992 G R Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1056 D E Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1064 R W Polymorphism
1097 L I Polymorphism
1114 R C Disease Arterial calcification of infancy, generalized, 2 (GACI2) [MIM:614473]
1121 S L Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1130 T M Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1133 G A Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1138 R Q Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1139 A T Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1164 R Q Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1203 G D Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1221 R H Disease Arterial calcification of infancy, generalized, 2 (GACI2) [MIM:614473]
1226 L I Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1235 R W Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1238 D H Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1241 W C Polymorphism
1268 R Q Polymorphism
1298 V F Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1301 T I Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1302 G R Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1303 A P Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1314 R W Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1321 G S Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1335 L P Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1339 R C Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1346 P S Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1347 Q H Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1354 G R Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1357 R W Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1361 D N Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1400 E K Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1406 Q K Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1424 I T Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]
1442 A T Unclassified
1459 R C Disease Pseudoxanthoma elasticum (PXE) [MIM:264800]