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Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

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PDB 
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Phospho-sites

Showing 6 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
492 PhosphoS UP, PRIDE Combined yes
517 PhosphoS PRIDE
526 PhosphoT PRIDE
578 PhosphoS PRIDE yes
599 PhosphoT UP, PRIDE Combined yes
601 PhosphoS PRIDE yes

3D structure is not available

Display Settings

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Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 7 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
492 490 501 3 6
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD001060 3 Fe-IMAC column based phospho enrichment Homo sapiens (Human) PARTIAL 2015-08-19 Epithelial cell -
PXD000836 1 HOPE-fixation of lung tissue allows retrospective proteome and phosphoproteome studies Homo sapiens (Human) PARTIAL 2014-05-22 lung -
PXD000612 3 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD001333 4 Anion-Exchange Chromatography of Tryptic and Phosphopeptides: WAX vs. SAX and AEX vs. ERLIC Homo sapiens (Human) PARTIAL 2015-04-23 HeLa cell -
PXD005366 14 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture
PXD000680 2 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell -
492 491 501 2 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD005366 11 Robust, sensitive and automated phosphopeptide enrichment optimized for low sample amounts applied to primary hippocampal neurons Homo sapiens (Human),Rattus norvegicus (Rat) PARTIAL 2016-12-14 cell culture
517 508 532 10 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD003531 1 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell
526 508 532 19 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD003531 1 Proteomics of Primary cells derived from Ovarian Cancer Homo sapiens (Human) PARTIAL 2017-04-03 primary cell
578 575 581 4 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture
599 597 609 3 2
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 12 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture -
PXD004452 2 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
601 597 609 5 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 1 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture

Structures

Showing 29 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
4GQ4 A X-ray 1.2699999809265137 Monomer [SO4]A:610 0.03326536
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 68.14353942871094 0.0
4OG4 A X-ray 1.4500000476837158 Monomer [SO4]A:601 0.077032894
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 73.39293670654297 0.0
4GPQ A X-ray 1.4600000381469727 Monomer A 0.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 70.02778625488281 0.0
4OG6 A X-ray 1.4900000095367432 Monomer [SO4]A:601 0.077474296
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 69.16130828857422 0.0
5DB0 A X-ray 1.5 Monomer [SO4]A:604 0.038894564
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 74.98558807373047 0.0
4OG8 A X-ray 1.5299999713897705 Monomer [SO4]A:604 0.036733665
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 75.85957336425781 0.0
5DB2 A X-ray 1.5399999618530273 Monomer [SO4]A:606 0.034091923
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 75.5016098022461 0.0
5DDB A X-ray 1.5399999618530273 Monomer [SO4]A:613 0.036991686
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 70.06468200683594 0.0
4GQ6 A X-ray 1.5499999523162842 2 [SO4]A:602 0.28330362
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 66.49800109863281 0.0
4GQ3 A X-ray 1.559999942779541 Monomer [SO4]A:611 0.023912702
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 73.45059204101562 0.0
4X5Y A X-ray 1.590000033378601 Monomer [SO4]A:605 0.04603385
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 70.08476257324219 0.0
5DDC A X-ray 1.6200000047683716 Monomer A 0.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 72.22342681884766 0.0
5DD9 A X-ray 1.6200000047683716 Monomer [SO4]A:611 0.042958915
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 70.25296020507812 0.0
4OG5 A X-ray 1.6299999952316284 Monomer [SO4]A:602 0.057135735
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 70.6042251586914 0.0
5DDF A X-ray 1.659999966621399 Monomer [SO4]A:610 0.04917419
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 71.1675796508789 0.0
5DB3 A X-ray 1.7100000381469727 Monomer [SO4]A:604 0.035978805
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 76.99566650390625 0.0
5DDE A X-ray 1.7799999713897705 Monomer [SO4]A:603 0.042374305
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 68.007080078125 0.0
5DDA A X-ray 1.8300000429153442 Monomer [SO4]A:612 0.0329908
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 71.63478088378906 0.0
5DB1 A X-ray 1.8600000143051147 Monomer [SO4]A:606 0.027170138
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 70.06610107421875 0.0
4X5Z A X-ray 1.8600000143051147 Monomer [SO4]A:604 0.036345217
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 73.38949584960938 0.0
4OG3 A X-ray 2.009999990463257 Monomer [SO4]A:601 0.08202228
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 77.14196014404297 0.0
4OG7 A X-ray 2.0799999237060547 Monomer [SO4]A:601 0.10435542
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 64.63330841064453 0.0
5DDD A X-ray 2.140000104904175 Monomer [SO4]A:605 0.0326117
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 70.4285888671875 0.0
3U84 A X-ray 2.5 2 B 1.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
526 521 THR C 0.79 127.32569122314453 0.0
530 525 THR C 0.87 87.7676773071289 0.0
578 573 SER H 1 76.872314453125 1.2827593088150024
601 596 SER C 1 147.94398498535156 0.0
6B41 A X-ray 2.609999895095825 Monomer [7PR]A:703 0.03795117
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
526 461 THR C 0.79 143.82159423828125 0.0
530 465 THR C 0.87 144.25320434570312 0.0
578 573 SER H 1 81.18960571289062 0.0
3U86 A X-ray 2.8399999141693115 2 B 1.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
526 521 THR C 0.79 125.04740905761719 0.0
530 525 THR C 0.87 142.52268981933594 0.0
578 573 SER H 1 69.15396118164062 0.0
3U88 A X-ray 3.0 6 M 0.46190718
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
578 573 SER H 1 84.04722595214844 0.0
3U85 A X-ray 3.0 4 A 1.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
526 521 THR C 0.79 126.84161376953125 0.0
530 525 THR C 0.87 139.9766082763672 0.0
578 573 SER H 1 73.07929992675781 23.850576400756836
4I80 A X-ray 3.0999999046325684 4 A 1.0
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
526 521 THR C 0.79 133.7230682373047 0.0
530 525 THR C 0.87 139.15638732910156 0.0
578 573 SER H 1 72.19535827636719 23.372196197509766

Mutations

Showing 85 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
12 P L Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
22 L R Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
26 E K Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
39 L W Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
42 G D Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
45 E G Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
98 R L Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
110 G E Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
135 K I Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
139 H P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
144 F V Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
147 I F Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
157 L W Unclassified Parathyroid tumors
158 D V Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
159 S I Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
160 S F Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
161 G D Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
165 A P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
167 V F Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
169 A D Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
170 C R Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
173 L P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
176 R Q Polymorphism
177 D Y Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
181 A P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
184 E Q Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
186 H R Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
188 W R Unclassified Parathyroid tumor
189 V E Disease
220 V M Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
228 L P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
230 G R Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
234 R L Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
245 V F Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
246 C R Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
247 A V Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
258 S W Unclassified Parathyroid tumor
260 E K Disease
264 L R Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
265 Q P Disease
269 L P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
272 L P Disease
279 E A Unclassified Parathyroid tumor
282 P H Disease
286 G R Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
289 A P Unclassified Parathyroid tumor
291 L P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
310 G D Disease
314 A P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
316 T P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
319 R P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
322 H Y Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
325 P R Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
330 A P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
342 A D Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
346 W R Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
347 A P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
349 T R Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
353 I N Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
358 Y D Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
360 R W Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
362 D H Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
364 E K Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
373 A D Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
377 I M Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
378 P S Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
390 A V Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
416 A P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
418 L R Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
419 L P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
420 R P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
423 D H Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
426 C Y Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
428 W S Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
432 S R Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
441 W R Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
449 L P Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
452 F S Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
476 W C Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
532 R C Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
545 P S Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
546 T A Polymorphism
549 P S Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]
557 T S Polymorphism
560 S N Disease Familial multiple endocrine neoplasia type I (MEN1) [MIM:131100]