Welcome to Scop3P

Search for the desired protein with Uniprot accession, protein name/keyword, ProteomeXchange ID or PDB id

Ex.: O00571, ddx3x (keyword), ATP-dependent RNA helicase DDX3X, PXD000680 or 3JRV

  • Zoom in and zoom out (both with mouse and buttons on the right top corner) to see modificationson the protein
  • Slide the chart to see other modifications (both with mouse and buttons on the right topcorner)
  • Hover on the modification to see more information and position on the structure.
PDB 
 AlphaFold
Phospho-sites

Showing 4 results

Swiss-Prot Position Modification Source Evidence Singly phosphorylated
48 PhosphoT PRIDE yes
706 PhosphoT PRIDE yes
1703 PhosphoS PRIDE yes
1910 PhosphoY PRIDE yes

3D structure is not available

Display Settings

Hover over to see the values, zoom (in/out) or drag by using the mouse pointer.

Phosphorylated amino acids are colored red on the inner ring.

The first amino acid of the protein sequence is colored darker on each ring.

Phospho peptides

Showing 4 results

Sequence Modified position (Swiss-Prot) Peptide start Peptide end Modified position (Peptide) Number of projects
48 18 52 31 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD004452 2 HeLa proteome of 12,250 protein-coding genes Homo sapiens (Human) PARTIAL 2017-06-12 liver,colon
706 706 716 1 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000680 1 Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination Homo sapiens (Human) COMPLETE 2014-04-15 HeLa cell,HEK-293 cell
1703 1693 1709 11 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD002286 2 Phospo-proteomic profiling of Castration Resistant Prostate Cancer Homo sapiens (Human) PARTIAL 2016-08-19 -
1910 1899 1912 12 1
ProteomeXchange accession Peptide frequency Project Title Species Submission Type Publication Date Tissues USI
PXD000612 2 Ultra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling Homo sapiens (Human) PARTIAL 2014-08-06 cell culture

Structures

Showing 5 results

PDB id Chain Method Resolution Stoichiometry Interfacing Molecule/Chain Complex Formation Significance Score (CSS) P-sites View Structure
2YD6 A X-ray 1.350000023841858 2 [CL]A:1222 0.09697363 48
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
34 34 THR E 0.94 33.45918655395508 0.0
37 37 SER C 0.94 40.466590881347656 0.0
48 48 THR E 0.9 47.58250045776367 0.0
205 199 TYR E 1.0 2.0126917362213135 0.0
2YD7 A X-ray 1.9800000190734863 Monomer [PO4]A:1221 0.044517245 48
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
34 34 THR E 0.94 33.871070861816406 0.0
37 37 SER C 0.94 44.88902282714844 0.0
48 48 THR E 0.9 63.507347106933594 0.0
205 199 TYR E 1.0 1.5508034229278564 0.0
4RCA A X-ray 2.990000009536743 Monomer B 0.0 48
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
34 34 THR E 0.94 34.75857925415039 0.0
37 37 SER C 0.94 33.97826385498047 0.0
48 48 THR E 0.9 66.66080474853516 0.0
205 205 TYR E 1.0 4.4686737060546875 0.0
5WY8 A X-ray 3.069999933242798 4 B 1.0 48
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
34 34 THR E 0.94 25.778478622436523 0.0
37 37 SER C 0.94 24.20345687866211 1.2961243391036987
48 48 THR E 0.9 63.86922836303711 0.0
205 205 TYR E 1.0 3.8479995727539062 0.0
5XNP D X-ray 3.7300000190734863 4 A 0.16742131 48
Swiss-Prot position PDB position Residue Secondary Structure Conserved Scale Accessible surface area Buried surface area
34 34 THR E 0.94 31.718935012817383 0.0
37 37 SER C 0.94 41.31553268432617 0.0
48 48 THR E 0.9 58.289093017578125 0.0
205 196 TYR E 1.0 2.550265312194824 0.0

Mutations

Showing 6 results

Swiss-Prot Position Amino acid (Wild type) Amino acid (Variant) Variant Type Disease
28 R Q Unclassified A colorectal cancer sample
276 L P Unclassified A colorectal cancer sample
447 Q E Polymorphism
901 V A Unclassified A colorectal cancer sample
995 R C Polymorphism
1078 E D Polymorphism